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Five weeks after fracture the femora were analysed by mechanical and histological testing. The groups with the lower vitamin C intake demonstrated a lower mechanical resistance of the healing callus and a lower histological grade. The vitamin C levels in blood during healing correlated with the torque resistance of the callus formed (r = 0.525). Therefore, the supplementary vitamin C improved the mechanical resistance of the fracture callus in elderly rats. If these results are similar in humans, vitamin C supplementation should be recommended during fracture healing in the elderly. <\/jats:p>","DOI":"10.1302\/0301-620x.89b3.18007","type":"journal-article","created":{"date-parts":[[2007,3,13]],"date-time":"2007-03-13T19:09:59Z","timestamp":1173812999000},"page":"402-407","source":"Crossref","is-referenced-by-count":29,"title":["Effect of vitamin C on fracture healing in elderly Osteogenic Disorder Shionogi rats"],"prefix":"10.1302","volume":"89-B","author":[{"given":"T.","family":"Alcantara-Martos","sequence":"first","affiliation":[{"name":"Hospital \u201cSan Agustin\u201d, Avda de San Cristobal S\/N, 23700 Linares, Ja\u00e9n, Spain."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. D.","family":"Delgado-Martinez","sequence":"additional","affiliation":[{"name":"Department of Surgery Ed. 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