{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T17:46:15Z","timestamp":1761155175691},"reference-count":21,"publisher":"British Editorial Society of Bone & Joint Surgery","issue":"4","license":[{"start":{"date-parts":[[2008,4,1]],"date-time":"2008-04-01T00:00:00Z","timestamp":1207008000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/online.boneandjoint.org.uk\/TDM"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Bone and Joint Surgery. British volume"],"published-print":{"date-parts":[[2008,4]]},"abstract":"<jats:p> With advances in the treatment of patients with chronic renal failure, their life expectancy has increased. In turn, the prevalence of osteitis fibrosa cystica, a manifestation of secondary hyperparathyroidism, and \u03b22 microglobulin amyloidosis, a result of long-term haemodialysis, has risen. While both conditions share similar radiological features, their management is very different. <\/jats:p><jats:p> We present the case of a patient with renal failure who had been receiving haemodialysis for over 20 years. Lytic lesions had been observed in the proximal part of both femurs for ten years. A presumptive diagnosis of osteitis fibrosa cystica was made. However, no regression of the lesions occurred after parathyroidectomy. The patient subsequently developed sequential pathological fractures through the lesions, for which bilateral total hip replacements were performed. Histology of the lesions revealed that the patient was in fact suffering from amyloidosis. <\/jats:p><jats:p> In patients with chronic renal failure, osseous amyloidosis is a highly probable differential diagnosis, especially if no regression of a lytic lesion is observed after parathyroidectomy. <\/jats:p>","DOI":"10.1302\/0301-620x.90b4.20308","type":"journal-article","created":{"date-parts":[[2008,3,31]],"date-time":"2008-03-31T21:23:15Z","timestamp":1206998595000},"page":"506-509","source":"Crossref","is-referenced-by-count":8,"title":["Unresolved lytic lesions following parathyroidectomy in a patient with chronic renal failure"],"prefix":"10.1302","volume":"90-B","author":[{"given":"W. M. M.","family":"Fok","sequence":"first","affiliation":[{"name":"Department of Orthopaedics and Traumatology, 51F, Professional Block, Queen Mary Hospital, Pokfulam Road, Hong Kong, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H. B.","family":"Leung","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics and Traumatology, 51F, Professional Block, Queen Mary Hospital, Pokfulam Road, Hong Kong, China."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"42","reference":[{"key":"R1","unstructured":"Pinto LP, Cherubinim K, Salum FG, Yurgel LS, de Fiqueiredo MA. Highly aggressive brown tumor in the jaw associated with tertiary hyperparathyroidism. Pediatr Dent 2006;28:543\u20136."},{"key":"R2","doi-asserted-by":"publisher","DOI":"10.1007\/BF03351064"},{"key":"R3","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2005-2518"},{"key":"R4","doi-asserted-by":"publisher","DOI":"10.1067\/msy.2002.119939"},{"key":"R5","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-004-7274-y"},{"key":"R6","doi-asserted-by":"crossref","unstructured":"Kulak CAM, Bandeira C, Voss D, et al. Marked improvement in bone mass after parathyroidectomy in osteitis fibrosa cystica. 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Emedicine: primary hyperparathyroidism.www.emedicine.com (date last accessed 9 April 2007)."},{"key":"R12","unstructured":"Khan AN, Jabeen F Emedicine: secondary hyperparathyroidism. www.emedicine.com (date last accessed 8 September 2005)."},{"key":"R13","doi-asserted-by":"publisher","DOI":"10.3171\/jns.2003.98.2.0417"},{"key":"R14","doi-asserted-by":"publisher","DOI":"10.1097\/01.BRS.0000127187.58944.FA"},{"key":"R15","doi-asserted-by":"crossref","unstructured":"Hsieh MC, Ko JY, Eng HL. Pathologic fracture of the distal femur in osteitis fibrosa cystica simulating metastatic disease. Arch Orthop Trauma Surg 2004;124:498\u2013501.","DOI":"10.1007\/s00402-004-0697-y"},{"key":"R16","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-200005000-00027"},{"key":"R17","doi-asserted-by":"publisher","DOI":"10.1007\/BF00197929"},{"key":"R18","doi-asserted-by":"crossref","unstructured":"Kamphuis AGA, Geerlings W, Hazenberg BP, Thijn CJ. Annual evaluation of hip joints and hands for radiographic signs of AB2M-amyloidosis in long-term haemodialysis patients. Skeletal Radiol 1994;23:421\u20137.","DOI":"10.1007\/BF00204602"},{"key":"R19","doi-asserted-by":"publisher","DOI":"10.1111\/j.1744-9987.2006.00383.x"},{"key":"R20","unstructured":"Gal R, Korzets A, Schwartz A, Rath-Wolfson L, Gafter U. Systemic distribution of Beta 2 microglobulin-derived amyloidosis in patients who undergo long-term haemodialysis: report of seven cases and review of the literature. Arch Pathol Lab Med 1994;118:718\u201321."},{"key":"R21","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.ndt.a027958"}],"container-title":["The Journal of Bone and Joint Surgery. 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