{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T18:06:22Z","timestamp":1793469982292,"version":"4.5.0"},"reference-count":14,"publisher":"British Editorial Society of Bone & Joint Surgery","issue":"7","license":[{"start":{"date-parts":[[2008,7,1]],"date-time":"2008-07-01T00:00:00Z","timestamp":1214870400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/online.boneandjoint.org.uk\/TDM"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Bone and Joint Surgery. British volume"],"published-print":{"date-parts":[[2008,7]]},"abstract":"<jats:p>We report 17 patients (20 hips) in whom metal-on-metal resurfacing had been performed and who presented with various symptoms and a soft-tissue mass which we termed a pseudotumour. Each patient underwent plain radiography and in some, CT, MRI and ultrasonography were also performed. In addition, histological examination of available samples was undertaken.<\/jats:p>\n                  <jats:p>All the patients were women and their presentation was variable. The most common symptom was discomfort in the region of the hip. Other symptoms included spontaneous dislocation, nerve palsy, a noticeable mass or a rash. The common histological features were extensive necrosis and lymphocytic infiltration. To date, 13 of the 20 hips have required revision to a conventional hip replacement. Two are awaiting revision.<\/jats:p>\n                  <jats:p>We estimate that approximately 1% of patients who have a metal-on-metal resurfacing develop a pseudotumour within five years. The cause is unknown and is probably multifactorial. There may be a toxic reaction to an excess of particulate metal wear debris or a hypersensitivity reaction to a normal amount of metal debris. We are concerned that with time the incidence of these pseudotumours may increase. Further investigation is required to define their cause.<\/jats:p>","DOI":"10.1302\/0301-620x.90b7.20213","type":"journal-article","created":{"date-parts":[[2008,6,30]],"date-time":"2008-06-30T17:38:26Z","timestamp":1214847506000},"page":"847-851","source":"Crossref","is-referenced-by-count":835,"title":["Pseudotumours associated with metal-on-metal hip resurfacings"],"prefix":"10.1302","volume":"90-B","author":[{"given":"H.","family":"Pandit","sequence":"first","affiliation":[{"name":"Nuffield Orthopaedic Centre"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Glyn-Jones","sequence":"additional","affiliation":[{"name":"Nuffield Department of Orthopaedic Surgery, University of Oxford, Nuffield Orthopaedic Centre, Oxford OX3 7LD, UK."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"McLardy-Smith","sequence":"additional","affiliation":[{"name":"Nuffield Orthopaedic Centre"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Gundle","sequence":"additional","affiliation":[{"name":"Nuffield Orthopaedic Centre"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Whitwell","sequence":"additional","affiliation":[{"name":"Nuffield Orthopaedic Centre"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. L. M.","family":"Gibbons","sequence":"additional","affiliation":[{"name":"Nuffield Orthopaedic Centre"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Ostlere","sequence":"additional","affiliation":[{"name":"Nuffield Orthopaedic Centre"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Athanasou","sequence":"additional","affiliation":[{"name":"Nuffield Department of Orthopaedic Surgery, University of Oxford, Nuffield Orthopaedic Centre, Oxford OX3 7LD, UK."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H. S.","family":"Gill","sequence":"additional","affiliation":[{"name":"Nuffield Department of Orthopaedic Surgery, University of Oxford, Nuffield Orthopaedic Centre, Oxford OX3 7LD, UK."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. W.","family":"Murray","sequence":"additional","affiliation":[{"name":"Nuffield Department of Orthopaedic Surgery, University of Oxford, Nuffield Orthopaedic Centre, Oxford OX3 7LD, UK."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"42","reference":[{"key":"R1","doi-asserted-by":"publisher","DOI":"10.5694\/j.1326-5377.2004.tb05771.x"},{"key":"R2","doi-asserted-by":"publisher","DOI":"10.1097\/01.blo.0000238871.07604.49"},{"key":"R3","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.87B4.15498"},{"key":"R4","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.A.02039pp"},{"key":"R5","doi-asserted-by":"crossref","unstructured":"Glyn-Jones S, Pandit H, Osler S, et al.\n                      Pseudotumours associated with metal-on-metal hip resurfacings. 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