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In two patients the diagnosis was proved by pre-operative biopsy, whereas all others were diagnosed on a clinicoradiological basis with confirmation obtained by histopathological examination and polymerase chain reaction of tissue samples taken at the time of surgery. All patients received chemotherapy for at least three months before surgery and treatment was continued for a total of 18 months. Post-operative dislocation occurred in one patient and was managed successfully by closed reduction. No reactivation of the infection or loosening of the implant was recorded and function of the hip improved in all patients. <\/jats:p><jats:p> Total hip replacement in the presence of active tuberculous arthritis of the hip is a safe procedure when pre-operative chemotherapy is commenced and continued for an extended period after operation. <\/jats:p>","DOI":"10.1302\/0301-620x.91b10.22541","type":"journal-article","created":{"date-parts":[[2009,9,30]],"date-time":"2009-09-30T21:33:15Z","timestamp":1254346395000},"page":"1301-1304","source":"Crossref","is-referenced-by-count":36,"title":["Total hip replacement in active advanced tuberculous arthritis"],"prefix":"10.1302","volume":"91-B","author":[{"given":"A. S.","family":"Sidhu","sequence":"first","affiliation":[{"name":"Department of Orthopaedics Government Medical College and Rajindra Hospital Patiala, Punjab 147001, India."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. P.","family":"Singh","sequence":"additional","affiliation":[{"name":"University College of Medical Sciences and associated Guru Teg Bahadur Hospital, Dilshad Garden, New Delhi 110095, India."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. P.","family":"Singh","sequence":"additional","affiliation":[{"name":"University College of Medical Sciences and associated Guru Teg Bahadur Hospital, Dilshad Garden, New Delhi 110095, India."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"42","reference":[{"key":"R1","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.59B3.893508"},{"key":"R2","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.63B1.7204469"},{"key":"R3","doi-asserted-by":"crossref","unstructured":"Liscomb PR, McCaslin FE Jr. Arthrodesis of the hip: review of 371 cases. 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