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We reviewed 1970 Sigma knees implanted in 920 women and 592 men with a mean age of 69.7 years. <\/jats:p><jats:p> At a mean follow-up of 7.3 years (minimum, five years), we found minimal differences in the outcome between genders. At the final follow-up, men had a higher overall Knee Society score and more osteolysis (3.8% vs 1.1%). However, there were no significant differences between men and women in terms of complications or improvements in knee function, pain score or range of movement. The estimated ten-year survivorship was 97% in women and 98% in men (p = 0.96). <\/jats:p><jats:p> We concluded that there was little difference in outcome between the genders treated by a modern unisex design of total knee replacement in this large multicentre study. <\/jats:p>","DOI":"10.1302\/0301-620x.91b3.21771","type":"journal-article","created":{"date-parts":[[2009,3,3]],"date-time":"2009-03-03T22:48:56Z","timestamp":1236120536000},"page":"357-360","source":"Crossref","is-referenced-by-count":58,"title":["Analysis of the outcome in male and female patients using a unisex total knee replacement system"],"prefix":"10.1302","volume":"91-B","author":[{"given":"D. F.","family":"Dalury","sequence":"first","affiliation":[{"name":"Towson Orthopaedic Associates, 8322 Bellona Avenue, Baltimore, Maryland 21204, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. 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