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Resection of the proximal humerus often includes the greater tuberosity and adjacent diaphysis, which may result in poor function secondary to loss of the rotator cuff and\/or deltoid function. Preservation of the joint with internal fixation may reduce the time in hospital and peri-operative morbidity compared with joint replacement, and result in a better functional outcome. We included 32 patients with pathological fractures of the proximal humerus in this study. Functional and radiological assessments were performed. At a mean follow-up of 17.6 months (8 to 61) there was no radiological evidence of failure of fixation. The mean revised musculoskeletal Tumour Society functional score was 94.6% (86% to 99%). There was recurrent tumour requiring further surgery in four patients (12.5%). Of the 22 patients who were employed prior to presentation all returned to work without restrictions. <\/jats:p><jats:p> The use of a locking plate combined with augmentation with cement extends the indications for salvage of the proximal humerus with good function in patients with pathological and impending pathological fractures. <\/jats:p>","DOI":"10.1302\/0301-620x.92b5.23246","type":"journal-article","created":{"date-parts":[[2010,4,30]],"date-time":"2010-04-30T23:25:18Z","timestamp":1272669918000},"page":"707-712","source":"Crossref","is-referenced-by-count":42,"title":["Pathological fractures of the proximal humerus treated with a proximal humeral locking plate and bone cement"],"prefix":"10.1302","volume":"92-B","author":[{"given":"H. 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