{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T21:16:09Z","timestamp":1792098969079,"version":"4.4.0"},"reference-count":28,"publisher":"British Editorial Society of Bone & Joint Surgery","issue":"8","license":[{"start":{"date-parts":[[2010,8,1]],"date-time":"2010-08-01T00:00:00Z","timestamp":1280620800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/online.boneandjoint.org.uk\/TDM"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Bone and Joint Surgery. British volume"],"published-print":{"date-parts":[[2010,8]]},"abstract":"<jats:p>We present a retrospective review of 167 patients aged 18 years and under who were treated for chronic haematogenous osteomyelitis at our elective orthopaedic hospital in Malawi over a period of four years. The median age at presentation was eight years (1 to 18). There were 239 hospital admissions for treatment during the period of the study. In 117 patients one admission was necessary, in 35 two, and in 15 more than two.<\/jats:p><jats:p>A surgical strategy of infection control followed by reconstruction and stabilisation was employed, based on the Beit CURE radiological classification of chronic haematogenous osteomyelitis as a guide to treatment. At a minimum follow-up of one year after the end of the study none of the patients had returned to our hospital with recurrent infection.<\/jats:p><jats:p>A total of 350 operations were performed on the 167 patients. This represented 6.7% of all children\u2019s operations performed in our hospital during this period. One operation only was required in 110 patients and none required more than three. Below-knee amputation was performed in two patients with chronic calcaneal osteomyelitis as the best surgical option for function. The most common organism cultured from operative specimens was Staphylococcus aureus, and the tibia was the bone most commonly affected. Polyostotic osteomyelitis occurred in four patients. We believe this is the largest reported series of patients treated for chronic haematogenous osteomyelitis.<\/jats:p>","DOI":"10.1302\/0301-620x.92b8.23413","type":"journal-article","created":{"date-parts":[[2010,7,31]],"date-time":"2010-07-31T23:17:50Z","timestamp":1280618270000},"page":"1138-1143","source":"Crossref","is-referenced-by-count":47,"title":["Chronic haematogenous osteomyelitis in children"],"prefix":"10.1302","volume":"92-B","author":[{"given":"V. L. L.","family":"Beckles","sequence":"first","affiliation":[{"name":"Barking, Havering and Redbridge University Hospitals, NHS Trust, Rom Valley Way, Romford, Essex RM7 0AG, UK."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H. Wynn","family":"Jones","sequence":"additional","affiliation":[{"name":"Wrightington Hospital, Hall Lane, Appley Bridge, Wigan, Lancashire WN6 9EP, UK."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W. J.","family":"Harrison","sequence":"additional","affiliation":[{"name":"Beit CURE International Hospital, PO Box 31236, Blantyre 3, Malawi."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"42","reference":[{"key":"R1","doi-asserted-by":"crossref","unstructured":"Daoud A, Saighi-Bouaouina A.Treatment of sequestra, pseudarthroses, and defects in the long bones of children who have chronic hematogenous osteomyelitis. J Bone Joint Surg [Am] 1989;71-A:1448\u201368.","DOI":"10.2106\/00004623-198971100-00003"},{"key":"R2","unstructured":"No authors listed.The state of the world\u2019s children: demographic indicators. Unicef, 2005. http:\/\/www.unicef.org\/sowc05\/english\/Table6_E.xls (date last accessed 26 March 2010)."},{"key":"R3","unstructured":"No authors listed.Malawi. United Nations Office of the High Representative for the Least Developed Countries, Landlocked Developing Countries and the Small Island Developing States (UN-OHRLLS), 2008. http:\/\/www.unohrlls.org\/en\/orphan\/103\/ (date last accessed 26 March 2010)."},{"key":"R4","unstructured":"No authors listed.2008 population and housing census: preliminary report. National Statistical Office of Malawi, 2008. http:\/\/www.nso.malawi.net\/data_on_line\/demography\/census_2008\/MWCensus08_report.pdf (date last accessed 26 March 2010)."},{"key":"R5","doi-asserted-by":"publisher","DOI":"10.1097\/BPO.0b013e3181b76933"},{"key":"R6","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.87B1.14656"},{"key":"R7","unstructured":"Cho SH, Song HR, Koo KH, Jeong ST, Park YJ.Antibiotic-impregnated cement beads in the treatment of chronic osteomyelitis. Bull Hosp Jt Dis 1997;56:140\u20134."},{"key":"R8","doi-asserted-by":"publisher","DOI":"10.1007\/BF02588391"},{"key":"R9","unstructured":"Agaja SB, Ayorinde RO.Chronic osteomyelitis in Ilorin, Nigeria. S Afr J Surg 2008;46:116\u201318."},{"key":"R10","doi-asserted-by":"crossref","unstructured":"Eyichukwu GO, Anyaehie UE.Outcome of management of chronic osteomyelitis at National Orthopaedic Hospital, Enugu. Niger J Med 2009;18:194\u20138.","DOI":"10.4314\/njm.v18i2.45064"},{"key":"R11","doi-asserted-by":"crossref","unstructured":"Lauschke FH, Frey CT.Hematogenous osteomyelitis in infants and children in the northwestern region of Namibia: management and two-year results. J Bone Joint Surg [Am] 1994;76-A:502\u201310.","DOI":"10.2106\/00004623-199404000-00004"},{"key":"R12","doi-asserted-by":"publisher","DOI":"10.1097\/BPB.0b013e3283195440"},{"key":"R13","doi-asserted-by":"crossref","unstructured":"Michelarakis J, Varouhaki C.Osteomyelitis of the calcaneus due to atypical Mycobacterium. Foot Ankle Surg 2009;18:106\u20138.","DOI":"10.1016\/j.fas.2008.07.003"},{"key":"R14","doi-asserted-by":"crossref","unstructured":"Alonge TO, Ogunlade SO, Omololu AB, Fashina AN, Oluwatosin A.Management of chronic osteomyelitis in a developing country using ceftriaxone-PMMA beads: an initial study. Int J Clin Pract 2002;56:181\u20133.","DOI":"10.1111\/j.1742-1241.2002.tb11229.x"},{"key":"R15","unstructured":"Onuminya JE, Onuminya DS.Results of open wound technique in the treatment of post-sequestrestomy dead space. S Afr J Surg 2008;46:26\u20137."},{"key":"R16","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.83B1.0830099"},{"key":"R17","doi-asserted-by":"publisher","DOI":"10.1177\/004947550203200216"},{"key":"R18","unstructured":"No authors listed.HIV\/AIDS: Malawi. United States Agency for International Development (USAID), 2008. http:\/\/www.usaid.gov\/our_work\/global_health\/aids\/Countries\/africa\/malawi.html (date last accessed 26 March 2010)."},{"key":"R19","unstructured":"Mehdi M, Yahiaoui MA, Arama M, Mammeri M, Isselnane R.Local antibiotic therapy in the form of gentamycin acrylic cement beads in the treatment of chronic osteomyelitis: apropos of 87 cases. 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