{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T15:56:14Z","timestamp":1780761374053,"version":"3.54.1"},"reference-count":25,"publisher":"British Editorial Society of Bone & Joint Surgery","issue":"10","license":[{"start":{"date-parts":[[2013,10,1]],"date-time":"2013-10-01T00:00:00Z","timestamp":1380585600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/online.boneandjoint.org.uk\/TDM"}],"content-domain":{"domain":["online.boneandjoint.org.uk"],"crossmark-restriction":true},"short-container-title":["The Bone &amp; Joint Journal"],"published-print":{"date-parts":[[2013,10]]},"abstract":"<jats:p>The main form of treatment of a chordoma of the mobile spine is total en bloc spondylectomy (TES), but the clinical results are not satisfactory. Stand-alone carbon ion radiotherapy (CIRT) for bone and soft-tissue sarcomas has recently been reported to have a high rate of local control with a low rate of local recurrence.<\/jats:p><jats:p>We report two patients who underwent TES after CIRT for treating a chordoma in the lumbar spine with good medium-term outcomes. At operation, there remained histological evidence of viable tumour cells in both cases. After the combination use of TES following CIRT, neither patient showed signs of recurrence at the follow-up examination. These two cases suggest that CIRT should be combined with total spondylectomy in the treatment of chordoma of the mobile spine.<\/jats:p><jats:p>Cite this article: Bone Joint J 2013;95-B:1392\u20135.<\/jats:p>","DOI":"10.1302\/0301-620x.95b10.31269","type":"journal-article","created":{"date-parts":[[2013,9,27]],"date-time":"2013-09-27T15:59:25Z","timestamp":1380297565000},"page":"1392-1395","update-policy":"https:\/\/doi.org\/10.1302\/crossmark-policy","source":"Crossref","is-referenced-by-count":13,"title":["Total spondylectomy following carbon ion radiotherapy to treat chordoma of the mobile spine"],"prefix":"10.1302","volume":"95-B","author":[{"given":"T.","family":"Matsumoto","sequence":"first","affiliation":[{"name":"Nagoya University Graduate School of Medicine, Department of Orthopaedic Surgery, 65 Tsurumai-cho, Showa-ku, Nagoya city, Aichi 466-8550, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Imagama","sequence":"additional","affiliation":[{"name":"Nagoya University Graduate School of Medicine, Department of Orthopaedic Surgery, 65 Tsurumai-cho, Showa-ku, Nagoya city, Aichi 466-8550, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Z.","family":"Ito","sequence":"additional","affiliation":[{"name":"Nagoya University Graduate School of Medicine, Department of Orthopaedic Surgery, 65 Tsurumai-cho, Showa-ku, Nagoya city, Aichi 466-8550, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Imai","sequence":"additional","affiliation":[{"name":"Research Center for Charged Particle Therapy, National Institute of Radiological Sciences (NIRS), 4-9-1 Anagawa, Inage-ku, Chiba city, Chiba 263-8555, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Kamada","sequence":"additional","affiliation":[{"name":"Research Center for Charged Particle Therapy, National Institute of Radiological Sciences (NIRS), 4-9-1 Anagawa, Inage-ku, Chiba city, Chiba 263-8555, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Shimoyama","sequence":"additional","affiliation":[{"name":"Nagoya University Graduate School of Medicine, Department of Pathology, 65 Tsurumai-cho, Showa-ku, Nagoya city, Aichi 466-8550, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Matsuyama","sequence":"additional","affiliation":[{"name":"Hamamatsu Medical University School of Medicine, Department of Orthopaedic Surgery, 1-20-1 Handayama, Higashi-ku, Hamamatsu city, Shizuoka 431-3192, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Ishiguro","sequence":"additional","affiliation":[{"name":"Nagoya University Graduate School of Medicine, Department of Orthopaedic Surgery, 65 Tsurumai-cho, Showa-ku, Nagoya city, Aichi 466-8550, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"42","reference":[{"key":"r1","first-page":"417","volume":"20","author":"Healey JH","year":"1989","journal-title":"Orthop Clin North Am"},{"key":"r2","doi-asserted-by":"publisher","DOI":"10.1023\/A:1008947301735"},{"key":"r3","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-198163030-00035"},{"key":"r4","doi-asserted-by":"publisher","DOI":"10.1097\/01.brs.0000200038.30869.27"},{"key":"r5","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-197812000-00009"},{"key":"r6","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0b013e3181b969ac"},{"key":"r7","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(11)70337-0"},{"key":"r8","doi-asserted-by":"publisher","DOI":"10.1269\/jrr.10016"},{"key":"r9","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1097\/00003086-198603000-00014","volume":"204","author":"Sundaresan N","year":"1986","journal-title":"Clin Orthop Rel Res"},{"key":"r10","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-199607010-00017"},{"key":"r11","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1993.78.5.0741"},{"key":"r12","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-8140(96)91805-8"},{"key":"r13","doi-asserted-by":"publisher","DOI":"10.1016\/0360-3016(83)90228-6"},{"key":"r14","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1982.56.3.0377"},{"key":"r15","doi-asserted-by":"publisher","DOI":"10.2307\/3583531"},{"key":"r16","doi-asserted-by":"publisher","DOI":"10.1097\/00000421-199008000-00013"},{"key":"r17","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2009.06.048"},{"key":"r18","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2009.10.051"},{"key":"r19","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0b013e3181caa86c"},{"key":"r20","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2008.08.058"},{"key":"r21","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2011.02.018"},{"key":"r22","doi-asserted-by":"publisher","DOI":"10.1080\/02841860500341157"},{"key":"r23","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6602754"},{"key":"r24","doi-asserted-by":"publisher","DOI":"10.1038\/nrclinonc.2009.183"},{"key":"r25","doi-asserted-by":"publisher","DOI":"10.1063\/1.3268510"}],"container-title":["The Bone &amp; Joint Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/online.boneandjoint.org.uk\/doi\/pdf\/10.1302\/0301-620X.95B10.31269","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/online.boneandjoint.org.uk\/doi\/full-xml\/10.1302\/0301-620X.95B10.31269","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/online.boneandjoint.org.uk\/doi\/pdf\/10.1302\/0301-620X.95B10.31269","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,7]],"date-time":"2022-03-07T01:06:36Z","timestamp":1646615196000},"score":1,"resource":{"primary":{"URL":"https:\/\/online.boneandjoint.org.uk\/doi\/10.1302\/0301-620X.95B10.31269"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,10]]},"references-count":25,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2013,10]]}},"alternative-id":["10.1302\/0301-620X.95B10.31269"],"URL":"https:\/\/doi.org\/10.1302\/0301-620x.95b10.31269","relation":{},"ISSN":["2049-4394","2049-4408"],"issn-type":[{"value":"2049-4394","type":"print"},{"value":"2049-4408","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,10]]},"assertion":[{"value":"2012-11-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-06-03","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-10-01","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}