{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T14:38:39Z","timestamp":1788187119332,"version":"build-2803163510"},"reference-count":74,"publisher":"Bioscientifica","issue":"2","license":[{"start":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T00:00:00Z","timestamp":1770854400000},"content-version":"vor","delay-in-days":3298,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.bioscientifica.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2017,2,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Platelet-rich plasma (PRP) is an autologous blood product with platelet concentrations above baseline values. The process involves the extraction of blood from the patient which is then centrifuged to obtain a concentrated suspension of platelets by plasmapheresis. It then undergoes a two-stage centrifugation process to separate the solid and liquid components of the anticoagulated blood. PRP owes its therapeutic use to the growth factors released by the platelets which are claimed to possess multiple regenerative properties. In the knee, PRP has been used in patients with articular cartilage pathology, ligamentous and meniscal injuries. There is a growing body of evidence to support its use in selected indications and this review looks at the most recent evidence. We also look at the current UK National Institute of Health &amp; Clinical Excellence (NICE) guidelines with respect to osteoarthritis and the use of PRP in the knee.<\/jats:p>\n                  <jats:p>Cite this article: EFORT Open Rev 2017;2:28\u201334. DOI: 10.1302\/2058-5241.2.160004.<\/jats:p>","DOI":"10.1302\/2058-5241.2.160004","type":"journal-article","created":{"date-parts":[[2017,2,1]],"date-time":"2017-02-01T20:10:26Z","timestamp":1485979826000},"page":"28-34","update-policy":"https:\/\/doi.org\/10.1530\/crossmarkpolicy-16","source":"Crossref","is-referenced-by-count":59,"title":["Platelet-rich plasma (PRP) for knee disorders"],"prefix":"10.1530","volume":"2","author":[{"given":"Mohammad","family":"Shahid","sequence":"first","affiliation":[{"name":"St Michael\u2019s Hospital, 30 Bond Street, Toronto, M5B1W8, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rik","family":"Kundra","sequence":"additional","affiliation":[{"name":"Walsall Manor Hospital, Moat Road, Walsall, WS2 9PS, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"416","published-online":{"date-parts":[[2017,2,1]]},"reference":[{"key":"2026070711170642600_bibr1-2058-5241.2.160004","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1097\/00008505-200110000-00002","article-title":"Platelet-rich plasma (PRP): what is PRP and what is not PRP?","volume":"10","author":"Marx","year":"2001","journal-title":"Implant Dent"},{"key":"2026070711170642600_bibr2-2058-5241.2.160004","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/0278-2391(94)90401-4","article-title":"Autologous fibrin adhesive in mandibular reconstruction with particulate cancellous bone and marrow","volume":"52","author":"Tayapongsak","year":"1994","journal-title":"J Oral Maxillofac Surg"},{"key":"2026070711170642600_bibr3-2058-5241.2.160004","doi-asserted-by":"crossref","first-page":"628","DOI":"10.2214\/AJR.10.5975","article-title":"Musculoskeletal applications of platelet-rich plasma: fad or 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