{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T17:16:21Z","timestamp":1783444581740,"version":"3.54.6"},"reference-count":19,"publisher":"Bioscientifica","issue":"4","license":[{"start":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T00:00:00Z","timestamp":1770940800000},"content-version":"vor","delay-in-days":1779,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.bioscientifica.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,4,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Low intensity pulsed ultrasound (LIPUS) therapy has demonstrated clinical effectiveness in achieving union in a variety of fracture situations. Few studies have investigated the effectiveness of LIPUS therapy in foot and ankle surgery. The overall rate of union in all published studies relating to the use of LIPUS in a variety of foot and ankle fracture and fusion situations is 95%. Some studies suggest lower healing rates (~ 67%) when LIPUS therapy is used to treat hindfoot fusion nonunion. A well-powered, high-quality, randomized controlled trial is needed to demonstrate the clinical and cost effectiveness of LIPUS therapy in foot and ankle surgery.<\/jats:p>\n                  <jats:p>Cite this article: EFORT Open Rev 2021;6:217-224. DOI: 10.1302\/2058-5241.6.200045<\/jats:p>","DOI":"10.1302\/2058-5241.6.200045","type":"journal-article","created":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T04:44:52Z","timestamp":1617252292000},"page":"217-224","update-policy":"https:\/\/doi.org\/10.1530\/crossmarkpolicy-16","source":"Crossref","is-referenced-by-count":6,"title":["The use of low intensity pulsed ultrasound in the foot and ankle"],"prefix":"10.1530","volume":"6","author":[{"given":"Mustafa S.","family":"Rashid","sequence":"first","affiliation":[{"name":"1Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences (NDORMS), University of Oxford, Oxford, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yves","family":"Tourn\u00e9","sequence":"additional","affiliation":[{"name":"2Institut Grenoblois de Chirurgie du Pied, Echirolles, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kar H.","family":"Teoh","sequence":"additional","affiliation":[{"name":"3Princess Alexandra Hospital, Harlow, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"416","published-online":{"date-parts":[[2021,4,1]]},"reference":[{"key":"2026070711334926600_bibr1-2058-5241.6.200045","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.3113\/FAI.2012.1031","article-title":"Current concepts review: risk factors for nonunions in foot and ankle arthrodeses","volume":"33","author":"Thevendran","year":"2012","journal-title":"Foot Ankle Int"},{"key":"2026070711334926600_bibr2-2058-5241.6.200045","doi-asserted-by":"crossref","first-page":"2309499017692703","DOI":"10.1177\/2309499017692703","article-title":"Perceived risk factors for nonunion following foot and ankle arthrodesis","volume":"25","author":"Thevendran","year":"2017","journal-title":"J Orthop Surg (Hong 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in the foot and ankle","volume":"26","author":"Majeed","year":"2020","journal-title":"Foot Ankle Surg"},{"key":"2026070711334926600_bibr9-2058-5241.6.200045","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1007\/BF00436764","article-title":"The stimulation of bone growth by ultrasound","volume":"101","author":"Duarte","year":"1983","journal-title":"Arch Orthop Trauma Surg"},{"key":"2026070711334926600_bibr10-2058-5241.6.200045","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.ultras.2016.03.016","article-title":"Mode and mechanism of low intensity pulsed ultrasound (LIPUS) in fracture repair","volume":"70","author":"Harrison","year":"2016","journal-title":"Ultrasonics"},{"key":"2026070711334926600_bibr11-2058-5241.6.200045","doi-asserted-by":"crossref","first-page":"S157","DOI":"10.1016\/S0301-5629(03)00634-3","article-title":"Ultrasonically induced motion in tissue during fracture treatment?","volume":"29","author":"Greenleaf","year":"2003","journal-title":"Ultrasound Med Biol"},{"key":"2026070711334926600_bibr12-2058-5241.6.200045","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/PL00021234","article-title":"Ultrasound: an alternative healing method for nonunions?","volume":"120","author":"Mayr","year":"2000","journal-title":"Arch Orthop Trauma Surg"},{"key":"2026070711334926600_bibr13-2058-5241.6.200045","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1186\/s12891-015-0498-1","article-title":"A cohort study of 4,190 patients treated with low-intensity pulsed ultrasound (LIPUS): findings in the elderly versus all patients","volume":"16","author":"Zura","year":"2015","journal-title":"BMC Musculoskelet Disord"},{"key":"2026070711334926600_bibr14-2058-5241.6.200045","doi-asserted-by":"crossref","first-page":"2584","DOI":"10.1016\/j.injury.2016.09.023","article-title":"Heal rate of metatarsal fractures: a propensity-matching study of patients treated with low-intensity pulsed ultrasound (LIPUS) vs. surgical and other treatments","volume":"47","author":"Nolte","year":"2016","journal-title":"Injury"},{"key":"2026070711334926600_bibr15-2058-5241.6.200045","doi-asserted-by":"crossref","first-page":"2036","DOI":"10.1016\/j.injury.2015.05.042","article-title":"Treatment of chronic (&gt; 1 year) fracture nonunion: heal rate in a cohort of 767 patients treated with low-intensity pulsed ultrasound (LIPUS)","volume":"46","author":"Zura","year":"2015","journal-title":"Injury"},{"key":"2026070711334926600_bibr16-2058-5241.6.200045","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1016\/j.fas.2018.11.004","article-title":"Is there a role for low intensity pulsed ultrasound (LIPUS) in delayed or nonunion following arthrodesis in foot and ankle surgery?","volume":"25","author":"Mirza","year":"2019","journal-title":"Foot Ankle 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EXOGEN ultrasound bone healing system for long bone fractures with non-union or delayed healing. In: (NICE) NIfHaCE, ed, 2013:1\u201328. https:\/\/www.nice.org.uk\/guidance\/mtg12\/chapter\/1-Recommendations (date last accessed 20 September 2020)."}],"container-title":["EFORT Open Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/online.boneandjoint.org.uk\/doi\/pdf\/10.1302\/2058-5241.6.200045","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/online.boneandjoint.org.uk\/doi\/full-xml\/10.1302\/2058-5241.6.200045","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.bioscientifica.com\/eor\/article-pdf\/6\/4\/217\/18008\/2058-5241.6.200045.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/journals.bioscientifica.com\/eor\/article-pdf\/6\/4\/217\/18008\/2058-5241.6.200045.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T16:18:18Z","timestamp":1783441098000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.bioscientifica.com\/eor\/article\/6\/4\/217\/2343\/The-use-of-low-intensity-pulsed-ultrasound-in-the"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4,1]]},"references-count":19,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2021,4,1]]},"published-print":{"date-parts":[[2021,4,1]]}},"URL":"https:\/\/doi.org\/10.1302\/2058-5241.6.200045","relation":{},"ISSN":["2058-5241"],"issn-type":[{"value":"2058-5241","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,4,1]]}}}