{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:33:54Z","timestamp":1787067234941,"version":"build-2736575974"},"reference-count":13,"publisher":"Royal College of Surgeons of England","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["annals"],"published-print":{"date-parts":[[2007,4]]},"abstract":"<jats:sec>\n                    <jats:title>INTRODUCTION<\/jats:title>\n                    <jats:p>C-reactive protein (CRP) is used routinely in many hospitals to evaluate patients with an acute abdomen. We assessed CRP levels in non-specific abdominal pain (NSAP) and surgical conditions requiring operative or non-operative intervention. The aim of this study was to identify a level of CRP that can be useful in differentiating these three groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>PATIENTS AND METHODS<\/jats:title>\n                    <jats:p>All patients older than 25 years and admitted with acute abdominal pain other than those requiring emergency surgery were included. CRP within 24 h was assessed in all patients. Various cut-off values (&lt; 6, &gt; 6\u201350, &gt; 50\u2013100, &gt; 100\u2013150 and &gt; 150 mg\/l) were used to identify a useful diagnostic level of CRP in the 3 groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>A total of 211 patients were prospectively evaluated \u2013 129 women and 82 men with a mean age of 62.4 years (range, 27\u201392 years). CRP was performed in 196 within 24 h of admission. Sixty had NSAP while 136 had a surgical condition, of whom 69 had an operation\/intervention while the rest were treated non-operatively. The median and interquartile (IQ) range for the three groups were: NSAP, 16 mg\/l and 7.75\u201385.75 mg\/l; surgical non-operative group, 75 mg\/l and 30.5\u2013150 mg\/l; and surgical-operative, 111 mg\/l and 42\u2013212 mg\/l, respectively. These results were statistically significant (P = 0.001). NSAP was diagnosed in 61% of patients at levels &lt; 6 mg\/l compared to 39% of patients in the surgical groups. At levels &gt; 150 mg\/l, NSAP was diagnosed in 15% of patients compared to only 54% and 31% for the operative and non-operative groups, respectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS<\/jats:title>\n                    <jats:p>Despite statistically significant differences between the three groups, no useful level of CRP could be identified to differentiate between patients with NSAP and those requiring operative or non-operative management.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1308\/003588407x168389","type":"journal-article","created":{"date-parts":[[2007,3,25]],"date-time":"2007-03-25T18:59:06Z","timestamp":1174849146000},"page":"233-237","source":"Crossref","is-referenced-by-count":34,"title":["Prospective Study on the Role of C-Reactive Protein (CRP) in Patients with an Acute Abdomen"],"prefix":"10.1308","volume":"89","author":[{"given":"TA","family":"Salem","sequence":"first","affiliation":[{"name":"Department of Surgery, Royal Alexandra Hospital Paisley, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"RG","family":"Molloy","sequence":"additional","affiliation":[{"name":"Department of Surgical Gastroenterology, Gartnavel General Hospital Glasgow, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"PJ","family":"O'Dwyer","sequence":"additional","affiliation":[{"name":"University Department of Surgery, Western Infirmary Glasgow, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"171","reference":[{"key":"b1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.325.7377.1387"},{"key":"b2","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.174.5.1741391"},{"key":"b3","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.168.1.8976942"},{"key":"b4","doi-asserted-by":"publisher","DOI":"10.1007\/BF01888571"},{"key":"b5","volume-title":"Oxford Textbook of Surgery","author":"Briton J","year":"2000"},{"key":"b6","doi-asserted-by":"publisher","DOI":"10.1007\/BF02047214"},{"key":"b7","first-page":"242","volume":"36","author":"Davies AH","year":"1991","journal-title":"J R Coll Surg Edinb"},{"key":"b8","doi-asserted-by":"publisher","DOI":"10.1007\/s004230050227"},{"key":"b9","doi-asserted-by":"publisher","DOI":"10.1007\/s002689910076"},{"key":"b10","doi-asserted-by":"publisher","DOI":"10.3109\/00365519709084584"},{"key":"b11","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.4464"},{"key":"b12","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-6757(96)90169-2"},{"key":"b13","doi-asserted-by":"publisher","DOI":"10.3109\/00365529409094902"}],"container-title":["The Annals of The Royal College of Surgeons of England"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/publishing.rcseng.ac.uk\/doi\/pdf\/10.1308\/003588407X168389","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,15]],"date-time":"2023-05-15T05:54:08Z","timestamp":1684130048000},"score":1,"resource":{"primary":{"URL":"https:\/\/publishing.rcseng.ac.uk\/doi\/10.1308\/003588407X168389"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,4]]},"references-count":13,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2007,4]]}},"alternative-id":["10.1308\/003588407X168389"],"URL":"https:\/\/doi.org\/10.1308\/003588407x168389","relation":{},"ISSN":["0035-8843","1478-7083"],"issn-type":[{"value":"0035-8843","type":"print"},{"value":"1478-7083","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,4]]}}}