{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T06:38:56Z","timestamp":1776321536899,"version":"3.50.1"},"reference-count":18,"publisher":"Royal College of Surgeons of England","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["annals"],"published-print":{"date-parts":[[2007,5]]},"abstract":"<jats:sec><jats:title>INTRODUCTION<\/jats:title><jats:p> Laparoscopic cholecystectomy has revolutionised the management of symptomatic gallstones and is increasingly performed as a day-case procedure. The aim of this study was to assess the impact of opioid patient-controlled analgesia (PCA) on elective laparoscopic cholecystectomy. <\/jats:p><\/jats:sec><jats:sec><jats:title>PATIENTS AND METHODS<\/jats:title><jats:p> In a prospective, non-randomised, observational study, 76 consecutive patients who underwent elective in-patient laparoscopic cholecystectomy were reviewed. Six patients with complicated gall stone disease and four patients who converted from laparoscopic to an open operation were excluded. <\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p> Of the 66 remaining in the study group, 25 patients received morphine-PCA and, of these, 9 were fit for discharge. In contrast, 41 patients did not receive PCA and, of these, 27 were fit for discharge (P &lt; 0.05). Median Aldrete score in the PCA group was 16 and in the non-PCA group 18 (P &lt; 0.05). Postoperative nausea and vomiting were more common in patients receiving a morphine-based PCA and with in those with higher anti-emetic requirement (10\/25 in PCA and 7\/41 non-PCA groups; P &lt; 0.05). <\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSIONS<\/jats:title><jats:p> Routine postoperative opioid PCA prolongs the recovery and in-patient stay following elective laparoscopic cholecystectomy. Its role in postoperative pain management in routine laparoscopic cholecystectomy should be questioned. <\/jats:p><\/jats:sec>","DOI":"10.1308\/003588407x183337","type":"journal-article","created":{"date-parts":[[2007,5,25]],"date-time":"2007-05-25T10:49:17Z","timestamp":1180090157000},"page":"374-378","source":"Crossref","is-referenced-by-count":14,"title":["The Impact of Patient-Controlled Analgesia on Laparoscopic Cholecystectomy"],"prefix":"10.1308","volume":"89","author":[{"given":"S","family":"Sinha","sequence":"first","affiliation":[{"name":"Department of General Surgery, Torbay Hospital Torquay, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V","family":"Munikrishnan","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Torbay Hospital Torquay, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Montgomery","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia, Torbay Hospital Torquay, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"SJ","family":"Mitchell","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Torbay Hospital Torquay, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"171","reference":[{"key":"b1","doi-asserted-by":"publisher","DOI":"10.1016\/S1089-9472(98)80075-0"},{"key":"b2","doi-asserted-by":"publisher","DOI":"10.1016\/0952-8180(94)00001-K"},{"key":"b3","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9610(05)81009-8"},{"key":"b4","doi-asserted-by":"publisher","DOI":"10.1007\/BF03010569"},{"key":"b5","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2044.1998.00314.x"},{"key":"b6","doi-asserted-by":"publisher","DOI":"10.2165\/00002512-199813010-00002"},{"key":"b7","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-199812000-00003"},{"key":"b8","first-page":"43","volume":"162","author":"Prasad A","year":"1996","journal-title":"Eur J Surg"},{"key":"b9","first-page":"461","volume":"49","author":"Serralta SA","year":"2002","journal-title":"Rev Esp Anestesiol Reanim"},{"key":"b10","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/87.1.36"},{"key":"b11","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1177\/0310057X9502300122","volume":"23","author":"Simes D","year":"1995","journal-title":"Anaesth Intensive Care"},{"key":"b12","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2044.1997.232-az0371.x"},{"key":"b13","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3959(93)90016-I"},{"key":"b14","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2044.1993.tb06824.x"},{"key":"b15","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800750307"},{"key":"b16","doi-asserted-by":"publisher","DOI":"10.1016\/S0020-1383(99)00308-3"},{"key":"b17","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-199211000-00022"},{"key":"b18","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-4295(95)97732-5"}],"container-title":["The Annals of The Royal College of Surgeons of England"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/publishing.rcseng.ac.uk\/doi\/pdf\/10.1308\/003588407X183337","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,15]],"date-time":"2023-05-15T09:53:48Z","timestamp":1684144428000},"score":1,"resource":{"primary":{"URL":"https:\/\/publishing.rcseng.ac.uk\/doi\/10.1308\/003588407X183337"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,5]]},"references-count":18,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2007,5]]}},"alternative-id":["10.1308\/003588407X183337"],"URL":"https:\/\/doi.org\/10.1308\/003588407x183337","relation":{},"ISSN":["0035-8843","1478-7083"],"issn-type":[{"value":"0035-8843","type":"print"},{"value":"1478-7083","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,5]]}}}