{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T06:09:43Z","timestamp":1777356583003,"version":"3.51.4"},"reference-count":7,"publisher":"Royal College of Surgeons of England","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["annals"],"published-print":{"date-parts":[[2008,5]]},"abstract":"<jats:sec><jats:title>INTRODUCTION<\/jats:title><jats:p> Appendicitis is the most common cause of the acute abdomen and can affect all age groups. Most patients recover quickly but a minority can suffer postoperative complications. This case-note review was undertaken to assess the frequency of these complications. <\/jats:p><\/jats:sec><jats:sec><jats:title>PATIENTS AND METHODS<\/jats:title><jats:p> Adult patients (&gt; 16 years) undergoing an emergency appendicectomy at a University teaching hospital between February 2004 and January 2005 were identified from pathology records. Details of operative procedure, histology and postoperative complications were noted from the hospital case notes <\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p> A total of 199 patients with a median age of 31 years (range, 16\u201389 years) were identified. Of these, 58 (29%) patients experienced a postoperative complication. Eight (4%) patients were admitted to the surgical high dependency unit or intensive care unit postoperatively and there was one death (0.5%). Re-operation for a postoperative complication was required in 9 (4.5%) patients and there was a 13% re-admission rate (26 patients). Comparison between patients with histologically proven appendicitis (164 patients; 82%) and those patients having a negative appendicectomy (35 patients; 18%) showed no significant difference in the rate of complications as defined (43 of 164, 26% versus 15 of 35, 43%; P = 0.08). However, patients with positive histology were more likely to experience a septic complication (29 of 164, 18% versus 1 of 35, 3%; P = 0.028) and all re-operations came from this group. Despite this, patients with a negative appendicectomy were more likely to be re-admitted (12 of 35, 34% versus 14 of 164, 8.5%; P = 0.0002), predominantly with persistent abdominal pain. <\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSIONS<\/jats:title><jats:p> Appendicectomy is associated with a significant morbidity. Patients with an inflamed appendix were more likely to experience a septic complication but re-admission was more common in patients with a histologically normal appendix because of unresolved abdominal pain. <\/jats:p><\/jats:sec>","DOI":"10.1308\/003588408x285973","type":"journal-article","created":{"date-parts":[[2008,5,7]],"date-time":"2008-05-07T02:01:23Z","timestamp":1210125683000},"page":"313-316","source":"Crossref","is-referenced-by-count":25,"title":["Acute Appendicitis \u2013 A Benign Disease?"],"prefix":"10.1308","volume":"90","author":[{"given":"J","family":"Simpson","sequence":"first","affiliation":[{"name":"Division of Gastrointestinal Surgery, Wolfson Digestive Disease Centre, Nottingham University Hospitals, Queen's Medical Centre Nottingham, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"APR","family":"Samaraweera","sequence":"additional","affiliation":[{"name":"Division of Gastrointestinal Surgery, Wolfson Digestive Disease Centre, Nottingham University Hospitals, Queen's Medical Centre Nottingham, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"RK","family":"Sara","sequence":"additional","affiliation":[{"name":"Division of Gastrointestinal Surgery, Wolfson Digestive Disease Centre, Nottingham University Hospitals, Queen's Medical Centre Nottingham, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"DN","family":"Lobo","sequence":"additional","affiliation":[{"name":"Division of Gastrointestinal Surgery, Wolfson Digestive Disease Centre, Nottingham University Hospitals, Queen's Medical Centre Nottingham, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"171","reference":[{"key":"b2","first-page":"529","author":"Simpson J","year":"2005","journal-title":"Clin Evidence"},{"key":"b3","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.4363"},{"key":"b4","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.4464"},{"key":"b5","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.185.2.01850406"},{"key":"b6","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-141-7-200410050-00011"},{"key":"b7","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2168.1999.01239.x"},{"key":"b8","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(98)10463-4"}],"container-title":["The Annals of The Royal College of Surgeons of England"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/publishing.rcseng.ac.uk\/doi\/pdf\/10.1308\/003588408X285973","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,15]],"date-time":"2023-05-15T09:57:38Z","timestamp":1684144658000},"score":1,"resource":{"primary":{"URL":"https:\/\/publishing.rcseng.ac.uk\/doi\/10.1308\/003588408X285973"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,5]]},"references-count":7,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2008,5]]}},"alternative-id":["10.1308\/003588408X285973"],"URL":"https:\/\/doi.org\/10.1308\/003588408x285973","relation":{},"ISSN":["0035-8843","1478-7083"],"issn-type":[{"value":"0035-8843","type":"print"},{"value":"1478-7083","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,5]]}}}