{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T13:07:24Z","timestamp":1789650444199,"version":"4.0.0"},"reference-count":34,"publisher":"Royal College of Surgeons of England","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["annals"],"published-print":{"date-parts":[[2008,9]]},"abstract":"<jats:sec><jats:title>INTRODUCTION<\/jats:title><jats:p>Pruritus ani is a common condition with many causes, predominately anorectal pathology. There are some new insights and therapies, but the most recommendations are based on low-level evidence.<\/jats:p><\/jats:sec><jats:sec><jats:title>PATIENTS AND METHODS<\/jats:title><jats:p>A literature search was carried out using Medline and the internet with the keywords \u2018pruritus ani\u2019 from 1950 to 2007.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>A review of the evidence is presented and a management plan based on the elimination of irritants and scratching, general control measures and active treatment measures is offered.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSIONS<\/jats:title><jats:p>Treatment of primary and secondary pruritus ani has a good prospect of regression of symptoms and skin changes.<\/jats:p><\/jats:sec>","DOI":"10.1308\/003588408x317940","type":"journal-article","created":{"date-parts":[[2008,8,30]],"date-time":"2008-08-30T21:53:54Z","timestamp":1220133234000},"page":"457-463","source":"Crossref","is-referenced-by-count":54,"title":["Pruritus Ani"],"prefix":"10.1308","volume":"90","author":[{"given":"S","family":"Siddiqi","sequence":"first","affiliation":[{"name":"Department of General Surgery, University College Hospital London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V","family":"Vijay","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Colchester General Hospital Colchester, Essex, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Ward","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Chase Farm Hospital Enfield, Middlesex, 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