{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,11]],"date-time":"2025-03-11T04:35:51Z","timestamp":1741667751301,"version":"3.38.0"},"reference-count":22,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2003,4,1]],"date-time":"2003-04-01T00:00:00Z","timestamp":1049155200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Primary Dental Care"],"published-print":{"date-parts":[[2003,4]]},"abstract":"<jats:p> Enamel matrix derivative (EMD) has recently been introduced as a new modality in regenerative periodontal therapy. This case report demonstrates a combined approach in topical application of EMD gel (Emdogain<jats:sup>\u00ae<\/jats:sup>) and autogenous bone grafts for treatment of intrabony defects and furcation involvement defects in a patient with chronic periodontitis. The seven-month post-surgery clinical and radiographic results were presented. The combined application of EMD gel with autogenous bone grafts in intrabony osseous defects resulted in clinically significant gain of attachment on diseased root surfaces and bone fill on radiographs. Further controlled clinical studies are required to confirm the long-term effectiveness of the combination of EMD gel and autogenous bone grafts in treatment of various osseous defects in subjects with chronic periodontitis. <\/jats:p>","DOI":"10.1308\/135576103322500700","type":"journal-article","created":{"date-parts":[[2003,10,26]],"date-time":"2003-10-26T00:32:55Z","timestamp":1067128375000},"page":"41-43","source":"Crossref","is-referenced-by-count":7,"title":["A Combined Approach of Enamel Matrix Derivative Gel and Autogenous Bone Grafts in Treatment of Intrabony Periodontal Defects. A Case Report"],"prefix":"10.1177","volume":"os10","author":[{"given":"George","family":"Leung","sequence":"first","affiliation":[{"name":"General Dental Practitioner, Hong Kong, PR China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lijian","family":"Jin","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry, Periodontology, The University of Hong Kong, Hong Kong, PR China."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2003,4,1]]},"reference":[{"key":"bibr1-135576103322500700","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1970.41.10.596"},{"key":"bibr2-135576103322500700","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1974.45.5.2.368"},{"key":"bibr3-135576103322500700","first-page":"295","volume":"19","author":"Wilson J","year":"1993","journal-title":"J Oral Implantol"},{"key":"bibr4-135576103322500700","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1995.66.2.125"},{"key":"bibr5-135576103322500700","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1976.47.9.497"},{"key":"bibr6-135576103322500700","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0757.1993.tb00204.x"},{"key":"bibr7-135576103322500700","doi-asserted-by":"publisher","DOI":"10.1016\/S8756-3282(96)00127-5"},{"key":"bibr8-135576103322500700","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1991.62.11.690"},{"key":"bibr9-135576103322500700","first-page":"9","volume":"13","author":"McClain PK","year":"1993","journal-title":"Int J Periodontics Restorative Dent"},{"key":"bibr10-135576103322500700","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1993.tb00402.x"},{"key":"bibr11-135576103322500700","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1994.65.3.244"},{"key":"bibr12-135576103322500700","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1997.tb00247.x"},{"key":"bibr13-135576103322500700","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1997.tb00249.x"},{"key":"bibr14-135576103322500700","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1997.tb00253.x"},{"key":"bibr15-135576103322500700","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1997.tb00252.x"},{"key":"bibr16-135576103322500700","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1999.70.3.255"},{"key":"bibr17-135576103322500700","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2000.71.12.1821"},{"key":"bibr18-135576103322500700","first-page":"8","volume":"19","author":"Mellonig JT.","year":"1999","journal-title":"Int J Periodontics Restorative Dent"},{"key":"bibr19-135576103322500700","first-page":"374","volume":"20","author":"Sculean A","year":"2000","journal-title":"Int J Periodontics Restorative Dent"},{"key":"bibr20-135576103322500700","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2000.71.7.1110"},{"key":"bibr21-135576103322500700","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1992.tb00641.x"},{"key":"bibr22-135576103322500700","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1990.61.6.319"}],"container-title":["Primary Dental Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1308\/135576103322500700","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1308\/135576103322500700","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,10]],"date-time":"2025-03-10T22:06:54Z","timestamp":1741644414000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1308\/135576103322500700"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,4]]},"references-count":22,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2003,4]]}},"alternative-id":["10.1308\/135576103322500700"],"URL":"https:\/\/doi.org\/10.1308\/135576103322500700","relation":{},"ISSN":["1355-7610","1741-9344"],"issn-type":[{"type":"print","value":"1355-7610"},{"type":"electronic","value":"1741-9344"}],"subject":[],"published":{"date-parts":[[2003,4]]}}}