{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T14:04:27Z","timestamp":1765807467939},"reference-count":5,"publisher":"Royal College of Surgeons of England","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["annals"],"published-print":{"date-parts":[[2017,9]]},"abstract":"<jats:p> Amphetamine induced ischaemic colitis is an exceedingly rare presentation of amphetamine toxicity. The cases reported in the literature have described mild or transient disease. We present a fatal case of ischaemic colitis induced by amphetamine use in a 44-year-old woman who presented in extremis after a cardiac arrest en route to the emergency department. A short history of headache, abdominal pain, vomiting and agitation preceded her admission. Imaging revealed changes consistent with ischaemic colitis. Emergency laparotomy revealed widespread colonic necrosis necessitating a subtotal colectomy. Despite aggressive resuscitation and inotropic support from arrival, the patient deteriorated intraoperatively and died in the immediate postoperative period. Histology showed arterial type ischaemia\/reperfusion injury of the area supplied by the superior mesenteric artery. The patient\u2019s serum amphetamine level was 0.52mg\/l (peak therapeutic levels &lt;0.2mg\/l). The postmortem examination concluded that amphetamines were the likely cause of the vasospasm, leading to profound colonic ischaemia. <\/jats:p>","DOI":"10.1308\/rcsann.2016.0350","type":"journal-article","created":{"date-parts":[[2017,8,30]],"date-time":"2017-08-30T13:47:38Z","timestamp":1504100858000},"page":"e200-e201","source":"Crossref","is-referenced-by-count":9,"title":["A fatal case of amphetamine induced ischaemic colitis"],"prefix":"10.1308","volume":"99","author":[{"given":"PA","family":"Green","sequence":"first","affiliation":[{"name":"Royal Liverpool and Broadgreen University Hospitals NHS Trust, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"CLF","family":"Battersby","sequence":"additional","affiliation":[{"name":"Royal Liverpool and Broadgreen University Hospitals NHS Trust, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"RM","family":"Heath","sequence":"additional","affiliation":[{"name":"Royal Liverpool and Broadgreen University Hospitals NHS Trust, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L","family":"McCrossan","sequence":"additional","affiliation":[{"name":"Royal Liverpool and Broadgreen University Hospitals NHS Trust, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"171","reference":[{"key":"bib1","doi-asserted-by":"publisher","DOI":"10.1097\/00004836-199112000-00015"},{"key":"bib2","doi-asserted-by":"publisher","DOI":"10.1016\/0735-6757(91)90073-S"},{"key":"bib3","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0096(199811\/12)26:9<479::AID-JCU9>3.0.CO;2-K"},{"key":"bib4","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.2009.139"},{"key":"bib5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1360-0443.2009.02564.x"}],"container-title":["The Annals of The Royal College of Surgeons of England"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/publishing.rcseng.ac.uk\/doi\/pdf\/10.1308\/rcsann.2016.0350","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,15]],"date-time":"2023-05-15T10:33:02Z","timestamp":1684146782000},"score":1,"resource":{"primary":{"URL":"https:\/\/publishing.rcseng.ac.uk\/doi\/10.1308\/rcsann.2016.0350"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,9]]},"references-count":5,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2017,9]]}},"alternative-id":["10.1308\/rcsann.2016.0350"],"URL":"https:\/\/doi.org\/10.1308\/rcsann.2016.0350","relation":{},"ISSN":["0035-8843","1478-7083"],"issn-type":[{"value":"0035-8843","type":"print"},{"value":"1478-7083","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,9]]}}}