{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,5,16]],"date-time":"2023-05-16T04:18:59Z","timestamp":1684210739057},"reference-count":24,"publisher":"Royal College of Surgeons of England","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["annals"],"published-print":{"date-parts":[[2019,2]]},"abstract":"<jats:p> We present the case of a 75-year-old man with a rapidly progressive cervical myelopathy on a background of a 3-year history of neck pain and a severely degenerative cervical spine. The patient developed progressive myelopathy over a six-month period and suffered from worsening kyphosis. Suspicion of an underlying oncological process prompted transfer to our tertiary referral unit. Biopsy was consistent for Paget\u2019s disease, an extremely rare diagnosis of the cervical spine. Magnetic resonance imaging revealed cord compression between C4 and C6 with associated cord signal change indicative of myelopathy. A three-level corpectomy and posterior instrumented fusion was performed. There was significant blood loss (3.5l) intraoperatively, consistent with a diagnosis of Paget\u2019s disease of the bone. Cell salvage was used, as was neuromonitoring for both the anterior and posterior part of the procedure. Postoperatively, neurological function improved slightly and the patient required community neurorehabilitation to allow independent living. <\/jats:p>","DOI":"10.1308\/rcsann.2018.0187","type":"journal-article","created":{"date-parts":[[2018,10,16]],"date-time":"2018-10-16T12:55:57Z","timestamp":1539694557000},"page":"e38-e42","source":"Crossref","is-referenced-by-count":0,"title":["A rare case of Paget\u2019s disease affecting the cervical spine"],"prefix":"10.1308","volume":"101","author":[{"given":"J","family":"Holton","sequence":"first","affiliation":[{"name":"Royal Orthopaedic Hospital NHS Foundation Trust, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Jones","sequence":"additional","affiliation":[{"name":"Royal Orthopaedic Hospital NHS Foundation Trust, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Z","family":"Klezl","sequence":"additional","affiliation":[{"name":"Derby Teaching Hospitals NHS Foundation Trust, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Czyz","sequence":"additional","affiliation":[{"name":"Royal Orthopaedic Hospital NHS Foundation Trust, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Grainger","sequence":"additional","affiliation":[{"name":"Royal Orthopaedic Hospital NHS Foundation Trust, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"Rehousek","sequence":"additional","affiliation":[{"name":"Royal Orthopaedic Hospital NHS Foundation Trust, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"171","reference":[{"key":"bib1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199702203360807"},{"key":"bib2","doi-asserted-by":"publisher","DOI":"10.1359\/jbmr.2004.19.4.566"},{"key":"bib3","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-015-3095-0"},{"key":"bib4","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.5650100318"},{"key":"bib5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbspin.2014.07.009"},{"key":"bib6","doi-asserted-by":"publisher","DOI":"10.1055\/s-2002-36730"},{"key":"bib7","doi-asserted-by":"publisher","DOI":"10.1359\/jbmr.06s214"},{"key":"bib8","doi-asserted-by":"publisher","DOI":"10.1016\/S0020-1383(08)70003-2"},{"key":"bib9","doi-asserted-by":"publisher","DOI":"10.5435\/JAAOS-21-01-51"},{"key":"bib10","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-007-0419-6"},{"issue":"9","key":"bib11","first-page":"S37","volume":"35","author":"Fehlings MG","year":"2010","journal-title":"Spine"},{"key":"bib12","doi-asserted-by":"publisher","DOI":"10.1007\/s00264-009-0853-7"},{"key":"bib13","first-page":"100","volume":"41","author":"Britton C","year":"2012","journal-title":"Aust Fam Physician"},{"key":"bib14","doi-asserted-by":"publisher","DOI":"10.1007\/s00256-006-0270-6"},{"key":"bib15","doi-asserted-by":"publisher","DOI":"10.1177\/095952877706000105"},{"key":"bib16","doi-asserted-by":"publisher","DOI":"10.1177\/1759720X09351779"},{"key":"bib17","doi-asserted-by":"publisher","DOI":"10.1007\/s005860100329"},{"key":"bib18","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-011-2133-7"},{"key":"bib19","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1097\/00003086-198704000-00006","volume":"217","author":"Meunier PJ","year":"1987","journal-title":"Clin Orthop Relat Res"},{"key":"bib20","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.68B3.2942548"},{"key":"bib21","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.10.7222"},{"key":"bib22","doi-asserted-by":"publisher","DOI":"10.1359\/jbmr.06s211"},{"key":"bib23","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1827.1995.tb03411.x"},{"key":"bib24","doi-asserted-by":"publisher","DOI":"10.1177\/1591019916637360"}],"container-title":["The Annals of The Royal College of Surgeons of England"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/publishing.rcseng.ac.uk\/doi\/pdf\/10.1308\/rcsann.2018.0187","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,15]],"date-time":"2023-05-15T10:15:13Z","timestamp":1684145713000},"score":1,"resource":{"primary":{"URL":"https:\/\/publishing.rcseng.ac.uk\/doi\/10.1308\/rcsann.2018.0187"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,2]]},"references-count":24,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2019,2]]}},"alternative-id":["10.1308\/rcsann.2018.0187"],"URL":"https:\/\/doi.org\/10.1308\/rcsann.2018.0187","relation":{},"ISSN":["0035-8843","1478-7083"],"issn-type":[{"value":"0035-8843","type":"print"},{"value":"1478-7083","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,2]]}}}