{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T20:10:40Z","timestamp":1773173440260,"version":"3.50.1"},"reference-count":5,"publisher":"Royal College of Surgeons of England","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["annals"],"published-print":{"date-parts":[[2020,5]]},"abstract":"<jats:p> Primary malignant fibrous histiocytoma, now classified as pleomorphic undifferentiated sarcoma, is the most common soft-tissue sarcoma in adult life. Primary splenic pleomorphic undifferentiated sarcoma is extremely rare and aggressive, and is associated with a poor prognosis; only 14 cases of splenic pleomorphic undifferentiated sarcoma have been documented in the English literature. We discuss a case of a 56-year-old woman with iron-deficiency anaemia, early satiety and left upper-quadrant pain, who was preoperatively diagnosed with a large splenic cyst following thorough investigation. This was excised in an elective procedure. Unfortunately, histology confirmed splenic pleomorphic undifferentiated sarcoma. Following a review and summary of the literature, we discuss key differentials between splenic cysts and splenic pleomorphic undifferentiated sarcoma. This case highlights that iron-deficiency anaemia is unusual in splenic cysts and more sinister causes must be considered. <\/jats:p>","DOI":"10.1308\/rcsann.2020.0035","type":"journal-article","created":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T15:25:51Z","timestamp":1585754751000},"page":"e105-e106","source":"Crossref","is-referenced-by-count":7,"title":["A splenic \u2018cyst\u2019: histology confirmed splenic sarcoma"],"prefix":"10.1308","volume":"102","author":[{"given":"DL","family":"Ashmore","sequence":"first","affiliation":[{"name":"Hull Royal Infirmary, Hull and East Yorkshire Hospitals NHS Trust, Hull, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D","family":"Dasgupta","sequence":"additional","affiliation":[{"name":"Hull Royal Infirmary, Hull and East Yorkshire Hospitals NHS Trust, Hull, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"171","reference":[{"key":"bib1","doi-asserted-by":"publisher","DOI":"10.4103\/0973-1482.95188"},{"key":"bib2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197806)41:6<2250::AID-CNCR2820410626>3.0.CO;2-W"},{"key":"bib3","first-page":"963","volume":"16","author":"Feng J","year":"2011","journal-title":"J Res Med Sci"},{"key":"bib4","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v20.i38.13899"},{"key":"bib5","doi-asserted-by":"publisher","DOI":"10.1177\/028418519403500510"}],"container-title":["The Annals of The Royal College of Surgeons of England"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/publishing.rcseng.ac.uk\/doi\/pdf\/10.1308\/rcsann.2020.0035","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,15]],"date-time":"2023-05-15T10:22:29Z","timestamp":1684146149000},"score":1,"resource":{"primary":{"URL":"https:\/\/publishing.rcseng.ac.uk\/doi\/10.1308\/rcsann.2020.0035"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,5]]},"references-count":5,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2020,5]]}},"alternative-id":["10.1308\/rcsann.2020.0035"],"URL":"https:\/\/doi.org\/10.1308\/rcsann.2020.0035","relation":{},"ISSN":["0035-8843","1478-7083"],"issn-type":[{"value":"0035-8843","type":"print"},{"value":"1478-7083","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,5]]}}}