{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,21]],"date-time":"2023-11-21T08:31:09Z","timestamp":1700555469550},"reference-count":7,"publisher":"Royal College of Surgeons of England","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["annals"],"published-print":{"date-parts":[[2020,7]]},"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p> Bilateral giant parathyroid adenoma in the absence of multiple endocrine neoplasia (MEN) type 1 is extremely rare and literature on this subject is limited. <\/jats:p><\/jats:sec><jats:sec><jats:title>Case history<\/jats:title><jats:p> A 79-year-old man presented with acute kidney injury secondary to hypercalcaemia. Blood test results indicated primary hyperparathyroidism. Ultrasonography revealed bilateral parathyroid adenomas measuring 19.4mm x 19.5mm x 18.8mm (left) and 15.2mm x 18.3mm x 19.6mm (left) whereas on computed tomography, the measurements were 31mm x 20mm (left) and 30mm x 14mm (right). Intraoperatively, giant adenomas measuring 50mm x 25mm x 12mm (left, weighing 8.101g) and 48mm x 22mm x 10mm (right, weighing 7.339g) were identified and excised. Parathyroid hormone level dropped from 44.6pmol\/l preoperatively to 8.9pmol\/l postoperatively (normal range 1.3\u20137.6pmol\/l). The patient was discharged with no complications. <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p> We report a rare phenomenon where bilateral giant parathyroid adenoma occurred in the absence of MEN type 1. It highlights the importance of cross-sectional imaging in delineating the anatomy of adenomas as their size can be grossly underestimated by ultrasonography alone. <\/jats:p><\/jats:sec>","DOI":"10.1308\/rcsann.2020.0043","type":"journal-article","created":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T15:35:16Z","timestamp":1585755316000},"page":"e111-e114","source":"Crossref","is-referenced-by-count":3,"title":["Bilateral giant parathyroid adenoma in the absence of multiple endocrine neoplasia type 1"],"prefix":"10.1308","volume":"102","author":[{"given":"P","family":"Liu","sequence":"first","affiliation":[{"name":"Nottingham University Hospitals NHS Trust, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N","family":"Vakharia","sequence":"additional","affiliation":[{"name":"Nottingham University Hospitals NHS Trust, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Zacharia","sequence":"additional","affiliation":[{"name":"United Lincolnshire Hospitals NHS Trust, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Rogers","sequence":"additional","affiliation":[{"name":"United Lincolnshire Hospitals NHS Trust, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F","family":"Tanweer","sequence":"additional","affiliation":[{"name":"United Lincolnshire Hospitals NHS Trust, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"171","reference":[{"key":"bib1","first-page":"167","volume":"5","author":"Bayraktar B","year":"2014","journal-title":"J Med Cases"},{"key":"bib2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-2197.1995.tb00634.x"},{"key":"bib3","first-page":"44","volume":"74","author":"Szymon \u015awirta J","year":"2017","journal-title":"Przegl Lek"},{"key":"bib4","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)60507-9"},{"key":"bib5","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2015.05.024"},{"key":"bib6","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2008.03.019"},{"key":"bib7","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2019182122"}],"container-title":["The Annals of The Royal College of Surgeons of England"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/publishing.rcseng.ac.uk\/doi\/pdf\/10.1308\/rcsann.2020.0043","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,15]],"date-time":"2023-05-15T10:13:07Z","timestamp":1684145587000},"score":1,"resource":{"primary":{"URL":"https:\/\/publishing.rcseng.ac.uk\/doi\/10.1308\/rcsann.2020.0043"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7]]},"references-count":7,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2020,7]]}},"alternative-id":["10.1308\/rcsann.2020.0043"],"URL":"https:\/\/doi.org\/10.1308\/rcsann.2020.0043","relation":{},"ISSN":["0035-8843","1478-7083"],"issn-type":[{"value":"0035-8843","type":"print"},{"value":"1478-7083","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,7]]}}}