{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T03:28:09Z","timestamp":1790306889092,"version":"4.1.0"},"reference-count":34,"publisher":"Royal College of Surgeons of England","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["annals"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Hashimoto\u2019s thyroiditis (HT) is one of the most common immune-mediated diseases. It makes thyroid surgery more complicated and difficult because there may be adhesions between the thyroid gland and surrounding structures. However, it is still controversial whether HT patients carry a high risk for postoperative complications of thyroid surgery. The purpose of this study was to investigate the significance of HT for the postoperative complications of thyroid surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A search for studies assessing the postoperative complication risks of HT patients compared with that of patients with benign nodules (BNs) was performed in PubMed, EMBASE and Web of Science. Nine studies (20,118 cases, 1,582 cases of HT and 18,536 cases of BN) were identified, and the data from the relevant outcomes were extracted and analysed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>There were no significant differences between the HT group and BN group in recurrent laryngeal nerve palsy (RLNP) and permanent hypoparathyroidism (PHP). The rate of transient hypocalcaemia (THC) was significantly higher in the HT group (16.85%) than in the BN group (13.20%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The meta-analysis showed that HT only increased the risk of the postoperative complication THC compared to BN. Understanding the significance of HT in postoperative hypoparathyroidism after thyroid surgery would help clinicians perform sufficient preoperative (and postoperative) assessments and to optimise surgical planning.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1308\/rcsann.2020.7013","type":"journal-article","created":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T07:02:08Z","timestamp":1614582128000},"page":"223-230","source":"Crossref","is-referenced-by-count":23,"title":["The significance of Hashimoto\u2019s thyroiditis for postoperative complications of thyroid surgery: a systematic review and meta-analysis"],"prefix":"10.1308","volume":"103","author":[{"given":"X","family":"Gan","sequence":"first","affiliation":[{"name":"Department of Thyroid Surgery, Guangzhou First People\u2019s Hospital, Guangzhou Medical University, Guangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J","family":"Feng","sequence":"additional","affiliation":[{"name":"Department of Thyroid Surgery, Guangzhou First People\u2019s Hospital, Guangzhou Medical University, Guangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"X","family":"Deng","sequence":"additional","affiliation":[{"name":"Department of Thyroid Surgery, Guangzhou First People\u2019s Hospital, Guangzhou Medical University, Guangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F","family":"Shen","sequence":"additional","affiliation":[{"name":"Department of Thyroid Surgery, Guangzhou First People\u2019s Hospital, Guangzhou Medical University, Guangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Colorectal and Anal Surgery, Guangzhou Digestive Disease Center, Guangzhou First People\u2019s Hospital, Guangzhou Medical University, Guangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Q","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Oncology, Guangzhou First People\u2019s Hospital, the Second Affiliated Hospital of South China University of Technology, Guangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W","family":"Cai","sequence":"additional","affiliation":[{"name":"Department of Thyroid Surgery, Guangzhou First People\u2019s Hospital, Guangzhou Medical University, Guangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Z","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Thyroid Surgery, Guangzhou First People\u2019s Hospital, the Second Affiliated Hospital of South China University of Technology, Guangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Thyroid Surgery, Guangzhou First People\u2019s Hospital, Guangzhou Medical University, Guangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Thyroid Surgery, Guangzhou First People\u2019s Hospital, Guangzhou Medical University, Guangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"171","reference":[{"key":"C1","first-page":"219","volume":"97","author":"Hashimoto H","year":"1912","journal-title":"Arch Klin Chir"},{"key":"C2","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-198106000-00013"},{"key":"C3","first-page":"243","volume":"38","author":"Gyory F","year":"1999","journal-title":"Acta Chir Hung"},{"key":"C4","doi-asserted-by":"publisher","DOI":"10.1272\/jnms.70.34"},{"key":"C5","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199607113350206"},{"key":"C6","doi-asserted-by":"publisher","DOI":"10.1586\/1744666x.3.2.217"},{"key":"C7","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6602097"},{"key":"C8","doi-asserted-by":"publisher","DOI":"10.1089\/thy.1994.4.333"},{"key":"C9","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2007.0384"},{"key":"C10","doi-asserted-by":"publisher","DOI":"10.1016\/j.otot.2017.12.002"},{"key":"C11","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2010.06.009"},{"key":"C12","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742-1241.2008.01875.x"},{"key":"C13","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.30360"},{"key":"C14","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9610(92)90391-4"},{"key":"C15","first-page":"493","volume":"116","author":"Proye C","year":"1990","journal-title":"Chirurgie; 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