{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T11:42:41Z","timestamp":1792755761909,"version":"4.5.0"},"reference-count":23,"publisher":"Royal College of Surgeons of England","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["annals"],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p> The aim of the study was to explore the feasibility of performing sentinel lymph node biopsy (SLNB) using a carbon nanoparticle suspension (CNPS) after neoadjuvant chemotherapy in breast cancer patients. <\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p> Some 152 patients diagnosed with primary breast cancer (cT1-3N0-2M0) were recruited. Patients were divided into two groups according to axillary lymph node (ALN) status after four to six cycles of neoadjuvant chemotherapy. All patients received a CNPS injection, after which SLNB and axillary lymph node dissection (ALND) were performed. <\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p> Sentinel lymph nodes (SLN) of 143 patients were identified; with an accuracy rate of 94.4% and a false-negative rate of 9.9%. Group A included 67 patients, and the detection, accuracy and false-negative rates within this group were 95.5%, 96.9% and 6.7%, respectively. The corresponding rates for group B (85 patients) were 92.9%, 92.4% and 11.8%, respectively. <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p> CNPS is an ideal tracer for improving the detection rate of SLN and can be used to determine SLN status following neoadjuvant chemotherapy. <\/jats:p><\/jats:sec>","DOI":"10.1308\/rcsann.2021.0084","type":"journal-article","created":{"date-parts":[[2021,8,27]],"date-time":"2021-08-27T13:15:44Z","timestamp":1630070144000},"page":"752-756","source":"Crossref","is-referenced-by-count":13,"title":["Sentinel lymph node biopsy with carbon nanoparticle suspension after neoadjuvant chemotherapy for breast cancer patients"],"prefix":"10.1308","volume":"103","author":[{"given":"N","family":"Wei","sequence":"first","affiliation":[{"name":"Guizhou Provincial People's Hospital, Guiyang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J","family":"Hou","sequence":"additional","affiliation":[{"name":"Guizhou Provincial People's Hospital, Guiyang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J","family":"Chen","sequence":"additional","affiliation":[{"name":"Guizhou Provincial People's Hospital, Guiyang, China"},{"name":"Guizhou Medical University, Guiyang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Dai","sequence":"additional","affiliation":[{"name":"Guizhou Provincial People's Hospital, Guiyang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K","family":"Du","sequence":"additional","affiliation":[{"name":"Guizhou Provincial People's Hospital, Guiyang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Wang","sequence":"additional","affiliation":[{"name":"Guizhou Provincial People's Hospital, Guiyang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Q","family":"Ni","sequence":"additional","affiliation":[{"name":"Guizhou Provincial People's Hospital, Guiyang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"171","reference":[{"key":"C1","doi-asserted-by":"publisher","DOI":"10.1016\/s1470-2045(13)70567-9"},{"key":"C2","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7819-8-6"},{"key":"C3","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-010-0945-z"},{"key":"C4","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-010-0973-1"},{"key":"C5","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2012.02.001"},{"key":"C6","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19821115)50:10<1979::aid-cncr2820501002\u2009>\u20093.0.co;2-d"},{"key":"C7","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-005-9025-7"},{"key":"C8","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6601150"},{"key":"C9","volume-title":"Breast Cancer (version.2.2015)","author":"NCCN Clinical Practice Guidelines in Oncology","year":"2015"},{"key":"C10","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.10986"},{"key":"C11","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.26102"},{"key":"C12","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdp322"},{"key":"C13","doi-asserted-by":"publisher","DOI":"10.1002\/jso.21911"},{"key":"C14","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.5209"},{"key":"C15","doi-asserted-by":"publisher","DOI":"10.3322\/canjclin.57.4.206"},{"key":"C16","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2013.278932"},{"key":"C17","doi-asserted-by":"publisher","DOI":"10.1016\/s1470-2045(13)70166-9"},{"key":"C18","doi-asserted-by":"publisher","DOI":"10.1016\/j.remn.2018.11.006"},{"key":"C19","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2008.06.1493"},{"key":"C20","doi-asserted-by":"publisher","DOI":"10.4048\/jbc.2018.21.e49"},{"key":"C21","doi-asserted-by":"publisher","DOI":"10.1186\/s12957-019-1582-z"},{"key":"C22","doi-asserted-by":"publisher","DOI":"10.1016\/s0959-8049(97)00376-6"},{"key":"C23","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2004.06.042"}],"container-title":["The Annals of The Royal College of Surgeons of England"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/publishing.rcseng.ac.uk\/doi\/pdf\/10.1308\/rcsann.2021.0084","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,15]],"date-time":"2023-05-15T10:22:46Z","timestamp":1684146166000},"score":1,"resource":{"primary":{"URL":"https:\/\/publishing.rcseng.ac.uk\/doi\/10.1308\/rcsann.2021.0084"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11]]},"references-count":23,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2021,11]]}},"alternative-id":["10.1308\/rcsann.2021.0084"],"URL":"https:\/\/doi.org\/10.1308\/rcsann.2021.0084","relation":{},"ISSN":["0035-8843","1478-7083"],"issn-type":[{"value":"0035-8843","type":"print"},{"value":"1478-7083","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,11]]}}}