{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T23:13:18Z","timestamp":1790809998801,"version":"4.1.0"},"reference-count":17,"publisher":"Royal College of Surgeons of England","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["annals"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p> It has been reported that excimer laser atherectomy combined with a drug-coated balloon (ELA+DCB) can achieve better results than simple balloon angioplasty, especially for the treatment of femoropopliteal in-stent restenosis. However, reports on the application of ELA+DCB in China for femoropopliteal arteriosclerosis obliterans are lacking. This study focuses on analysing the effectiveness and safety of ELA+DCB. <\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p> This was a single-centre retrospective study that enrolled patients from November 2016 to January 2019 who had femoropopliteal arteriosclerosis obliterans treated by ELA+DCB. Preoperative demographics, operative details and postoperative follow-up outcomes were analysed statistically. <\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p> There were 43 patients with an average patient age of 68.0\u00b18.6 years; 79.1% were male. In 30 cases, the lesions were de novo and the others were in-stent restenosis (ISR). During the procedure, flow-limiting dissection (48.8%) was the main adverse event and there were 17 bailout stent implantations due to dissection. Mean (\u00b1sd) ankle\u2013brachial index (ABI) in the patients was 0.42\u00b10.31 before the operation and 0.83\u00b10.13 before discharge. The mean (\u00b1sd) follow-up time was 29.35\u00b19.71 months. The primary patency rate was 66.8%, 64.3% and 60.9% at 12, 24 and 36 months. Freedom from target lesion revascularisation (TLR) was 85.7%, 80.7% and 75.3% at 12, 24 and 36 months. Rutherford categories also greatly improved during follow-up. Overall mortality was 6.9% (3\/48), and no deaths were related to the intervention. <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p> The use of ELA+DCB had good clinical benefit for femoropopliteal arteriosclerosis obliterans, which had good primary patency and freedom from TLR, although intraoperative complications still required attention. Multicentre randomised controlled trials with long-term follow-up are needed. <\/jats:p><\/jats:sec>","DOI":"10.1308\/rcsann.2021.0335","type":"journal-article","created":{"date-parts":[[2022,4,21]],"date-time":"2022-04-21T15:46:25Z","timestamp":1650555985000},"page":"667-672","source":"Crossref","is-referenced-by-count":7,"title":["Excimer laser atherectomy combined with  drug-coated balloon angioplasty for the treatment of femoropopliteal arteriosclerosis obliterans"],"prefix":"10.1308","volume":"104","author":[{"given":"Z","family":"Su","sequence":"first","affiliation":[{"name":"Xuanwu Hospital, Capital Medical University, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y","family":"Li","sequence":"additional","affiliation":[{"name":"Xuanwu Hospital, Capital Medical University, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Yang","sequence":"additional","affiliation":[{"name":"Xuanwu Hospital, Capital Medical University, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J","family":"Guo","sequence":"additional","affiliation":[{"name":"Xuanwu Hospital, Capital Medical University, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L","family":"Guo,","sequence":"additional","affiliation":[{"name":"Xuanwu Hospital, Capital Medical University, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y","family":"Gu","sequence":"additional","affiliation":[{"name":"Xuanwu Hospital, Capital Medical University, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"171","reference":[{"key":"C1","doi-asserted-by":"publisher","DOI":"10.1016\/j.carrev.2018.10.028"},{"key":"C2","first-page":"135","volume":"29","author":"Bhat TM","year":"2017","journal-title":"J Invasive Cardiol"},{"key":"C3","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2005.01.008"},{"key":"C4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2014.09.009"},{"key":"C5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2013.01.128"},{"key":"C6","doi-asserted-by":"publisher","DOI":"10.1177\/1526602817749587"},{"key":"C7","doi-asserted-by":"publisher","DOI":"10.1016\/j.avsg.2018.06.010"},{"key":"C8","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2013.05.022"},{"key":"C9","doi-asserted-by":"publisher","DOI":"10.1583\/13-4420R.1"},{"key":"C10","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.28636"},{"key":"C11","first-page":"1887","volume":"19","author":"Liu H","year":"2020","journal-title":"Exp Ther Med"},{"key":"C12","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.86.1.64"},{"key":"C13","doi-asserted-by":"publisher","DOI":"10.1007\/s00270-017-1649-6"},{"key":"C14","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(85)80435-6"},{"key":"C15","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.118.011245"},{"key":"C16","doi-asserted-by":"publisher","DOI":"10.1001\/jamacardio.2019.0325"},{"key":"C17","first-page":"655","volume":"55","author":"Diamantopoulos A","year":"2014","journal-title":"J Cardiovasc Surg (Torino)"}],"container-title":["The Annals of The Royal College of Surgeons of England"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/publishing.rcseng.ac.uk\/doi\/pdf\/10.1308\/rcsann.2021.0335","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,15]],"date-time":"2023-05-15T10:40:10Z","timestamp":1684147210000},"score":1,"resource":{"primary":{"URL":"https:\/\/publishing.rcseng.ac.uk\/doi\/10.1308\/rcsann.2021.0335"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11]]},"references-count":17,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2022,11]]}},"alternative-id":["10.1308\/rcsann.2021.0335"],"URL":"https:\/\/doi.org\/10.1308\/rcsann.2021.0335","relation":{},"ISSN":["0035-8843","1478-7083"],"issn-type":[{"value":"0035-8843","type":"print"},{"value":"1478-7083","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,11]]}}}