{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,2]],"date-time":"2025-04-02T04:19:48Z","timestamp":1743567588919,"version":"3.40.3"},"reference-count":4,"publisher":"Royal College of Surgeons of England","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["annals"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:p> We present a case of a 70-year-old gentleman who was referred to our tertiary 2-week-wait penile cancer clinic with a penile mass that was ulcerated, painful and discharging. This was suspicious for penile cancer and a radical circumcision was performed to remove the diseased foreskin en bloc with the lesion that was arising from the inner foreskin. Histopathology did not reveal cancer; however, we identified spirochaetes in keeping with syphilis. This was confirmed on serology. The patient was referred to the genitourinary medicine team and treated with antibiotics. This case demonstrates a rare presentation of genital syphilis in an elderly gentleman initially referred with concerns of penile cancer. Although, rare, especially in this age group, syphilis should be considered as a differential diagnosis in a patient presenting with an ulcerated, discharging, firm penile mass, especially given that the incidence of syphilis has been rising in recent years. <\/jats:p>","DOI":"10.1308\/rcsann.2022.0143","type":"journal-article","created":{"date-parts":[[2024,4,2]],"date-time":"2024-04-02T08:12:21Z","timestamp":1712045541000},"page":"310-312","source":"Crossref","is-referenced-by-count":0,"title":["A diagnosis of syphilis following a radical circumcision for suspected penile cancer"],"prefix":"10.1308","volume":"107","author":[{"given":"KH","family":"Pang","sequence":"first","affiliation":[{"name":"University College London Hospitals NHS Foundation Trust","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Haider","sequence":"additional","affiliation":[{"name":"University College London Hospitals NHS Foundation Trust","place":["UK"]},{"name":"University College London","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Freeman","sequence":"additional","affiliation":[{"name":"University College London Hospitals NHS Foundation Trust","place":["UK"]},{"name":"University College London","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"Hadway","sequence":"additional","affiliation":[{"name":"University College London Hospitals NHS Foundation Trust","place":["UK"]},{"name":"University College London","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"Bunker","sequence":"additional","affiliation":[{"name":"University College London Hospitals NHS Foundation Trust","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Muneer","sequence":"additional","affiliation":[{"name":"University College London Hospitals NHS Foundation Trust","place":["UK"]},{"name":"Division of Surgery and Interventional Science, University College London","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"HM","family":"Alnajjar","sequence":"additional","affiliation":[{"name":"University College London Hospitals NHS Foundation Trust","place":["UK"]},{"name":"Division of Surgery and Interventional Science, University College London","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"171","reference":[{"key":"C1","unstructured":"Public Health England. Addressing the increase in syphilis in England: PHE Action Plan. https:\/\/assets.publishing.service.gov.uk\/government\/uploads\/system\/uploads\/attachment_data\/file\/806076\/Addressing_the_increase_in_syphilis_in_England_Action_Plan_June_2019.pdf (cited January 2024)."},{"key":"C2","doi-asserted-by":"publisher","DOI":"10.1177\/0956462415624059"},{"key":"C3","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2020-238539"},{"key":"C4","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2020.08.034"}],"container-title":["The Annals of The Royal College of Surgeons of England"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/publishing.rcseng.ac.uk\/doi\/pdf\/10.1308\/rcsann.2022.0143","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T15:04:10Z","timestamp":1743519850000},"score":1,"resource":{"primary":{"URL":"https:\/\/publishing.rcseng.ac.uk\/doi\/10.1308\/rcsann.2022.0143"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4]]},"references-count":4,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,4]]}},"alternative-id":["10.1308\/rcsann.2022.0143"],"URL":"https:\/\/doi.org\/10.1308\/rcsann.2022.0143","relation":{},"ISSN":["0035-8843","1478-7083"],"issn-type":[{"type":"print","value":"0035-8843"},{"type":"electronic","value":"1478-7083"}],"subject":[],"published":{"date-parts":[[2025,4]]}}}