{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T12:18:42Z","timestamp":1769602722083,"version":"3.49.0"},"reference-count":13,"publisher":"Oxford University Press (OUP)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012,4,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>The goal of this study was to evaluate routine flow cytometric (FC) immunophenotypic markers in differentiating between Burkitt lymphoma (BL) and CD10+ diffuse large B-cell lymphoma (DLBCL). We performed retrospective analysis of FC data from 55 patients. We evaluated 9 FC parameters: forward and side scatter (FSC and SSC); mean fluorescent intensity (MFI) for CD20, CD10, CD38, CD79b, CD43, and CD71; and the percentage of neoplastic cells positive for CD71 (%CD71). The FSC; MFIs of CD10, CD43, CD79b, and CD71; and %CD71 cells were significantly different between BL and CD10+ DLBCL (P &amp;lt; .05; Student t test). A 5-point scoring system (FSC, %CD71, and MFIs of CD43, CD79b, and CD71) was devised, and 6 (60%) of 10 BLs scored 3 or greater and 1 (10%) of 10 CD10+ DLBCLs scored 3 (P = .04; \u03c72). Our findings indicate that routine FC parameters can aid in differentiating BL from CD10+ DLBCL.<\/jats:p>","DOI":"10.1309\/ajcp3fepx5beekgx","type":"journal-article","created":{"date-parts":[[2012,3,19]],"date-time":"2012-03-19T20:40:02Z","timestamp":1332189602000},"page":"665-670","source":"Crossref","is-referenced-by-count":24,"title":["Differentiating Between Burkitt Lymphoma and CD10+ Diffuse Large B-Cell Lymphoma"],"prefix":"10.1093","volume":"137","author":[{"given":"Paul","family":"McGowan","sequence":"first","affiliation":[{"name":"1Pathology and Laboratory Medicine, The Methodist Hospital, Houston, TX"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicole","family":"Nelles","sequence":"additional","affiliation":[{"name":"1Pathology and Laboratory Medicine, The Methodist Hospital, Houston, TX"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jana","family":"Wimmer","sequence":"additional","affiliation":[{"name":"1Pathology and Laboratory Medicine, The Methodist Hospital, Houston, TX"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dawn","family":"Williams","sequence":"additional","affiliation":[{"name":"1Pathology and Laboratory Medicine, The Methodist Hospital, Houston, TX"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianguo","family":"Wen","sequence":"additional","affiliation":[{"name":"1Pathology and Laboratory Medicine, The Methodist Hospital, Houston, TX"},{"name":"2Pathology and Laboratory Medicine, The Methodist Research Institute, Houston"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marilyn","family":"Li","sequence":"additional","affiliation":[{"name":"3Molecular and Human Genetics, Baylor College of Medicine, Houston"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"April","family":"Ewton","sequence":"additional","affiliation":[{"name":"1Pathology and Laboratory Medicine, The Methodist Hospital, Houston, TX"},{"name":"2Pathology and Laboratory Medicine, The Methodist Research Institute, Houston"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Choladda","family":"Curry","sequence":"additional","affiliation":[{"name":"4Texas Children\u2019s Hospital and Pathology, Baylor College of Medicine, Houston"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Youli","family":"Zu","sequence":"additional","affiliation":[{"name":"1Pathology and Laboratory Medicine, The Methodist Hospital, Houston, TX"},{"name":"2Pathology and Laboratory Medicine, The Methodist Research Institute, Houston"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Sheehan","sequence":"additional","affiliation":[{"name":"4Texas Children\u2019s Hospital and Pathology, Baylor College of Medicine, Houston"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chung-Che (Jeff)","family":"Chang","sequence":"additional","affiliation":[{"name":"5Pathology, University of Central Florida, and Hematology and Molecular Pathology, Department of Pathology, Florida Hospital, Orlando"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2012,4,1]]},"reference":[{"key":"2023011912111496800_b1-1370665","volume-title":"World Health Organization Classification of Tumours: Pathology and Genetics of Tumours of Haematopoietic and Lymphoid Tissues","author":"Swerdlow","year":"2001"},{"key":"2023011912111496800_b2-1370665","volume-title":"WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues","author":"Swerdlow","year":"2008","edition":"4th ed"},{"key":"2023011912111496800_b3-1370665","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.3324\/haematol.11263","article-title":"High-grade B-cell lymphoma\/leukemia associated with t(14;18) and 8q24\/MYC 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