{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T21:27:23Z","timestamp":1792272443613,"version":"4.4.0"},"reference-count":36,"publisher":"Oxford University Press (OUP)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Calculated low-density lipoprotein cholesterol (cLDL-C) may differ from direct measurement (dLDL-C), and this difference may depend on presence of small, dense LDL (sdLDL) particles in addition to variation in triglycerides (TG) and high-density lipoprotein cholesterol (HDL-C) concentrations. The presence of such dependence would offer a simple means to estimate sdLDL. We studied dependence of sdLDL on cLDL-C, dLDL-C, and other variables.<\/jats:p>\n                  <jats:p>We measured the levels of glucose, creatinine, total cholesterol, TG, HDL-C, and dLDL-C using standardized methods in 297 samples. For sdLDL cholesterol (sdLDL-C), a novel homogeneous assay was used. The cLDL-C was calculated using the Friedewald formula for 220 subjects after excluding for liver or renal disease. Using stepwise regression analysis identified non\u2013HDL-C, cLDL-C, and dLDL-C as significant variables (P &amp;lt; .001; R2 = 0.88). The regression equation was as follows: sdLDL-C (mg\/dL) = 0.580 (non\u2013HDL-C) + 0.407 (dLDL-C) \u2013 0.719 (cLDL-C) \u2013 12.05. The sdLDL-C concentration can be estimated from non\u2013HDL-C, dLDL-C, and cLDL-C values. Identification of a simple, inexpensive marker for sdLDL particles provides a cost-effective method for screening cardiovascular disease risk.<\/jats:p>","DOI":"10.1309\/ajcplhjbgg9l3ils","type":"journal-article","created":{"date-parts":[[2011,6,17]],"date-time":"2011-06-17T17:55:31Z","timestamp":1308333331000},"page":"20-29","source":"Crossref","is-referenced-by-count":48,"title":["Estimation of Plasma Small Dense LDL Cholesterol From Classic Lipid Measures"],"prefix":"10.1093","volume":"136","author":[{"given":"Pornpen","family":"Srisawasdi","sequence":"first","affiliation":[{"name":"1Department of Pathology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sirirat","family":"Chaloeysup","sequence":"additional","affiliation":[{"name":"1Department of Pathology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaovalak","family":"Teerajetgul","sequence":"additional","affiliation":[{"name":"2Department of Clinical Chemistry, Faculty of Associated Medical Science, Khonkaen University, Khonkaen, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anothai","family":"Pocathikorn","sequence":"additional","affiliation":[{"name":"3Department of Pathology, Faculty of Medicine, Prince of Songkla University, Songkla, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chonlaphat","family":"Sukasem","sequence":"additional","affiliation":[{"name":"1Department of Pathology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Somlak","family":"Vanavanan","sequence":"additional","affiliation":[{"name":"1Department of Pathology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, 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