{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T02:52:13Z","timestamp":1787021533780,"version":"build-2736575974"},"reference-count":0,"publisher":"Indian Orthopaedic Research Group","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JOCR"],"published-print":{"date-parts":[[2023]]},"abstract":"<jats:p>Introduction: Immunoglobulin (Ig)G4-related disease belongs to a rare compilation of conditions in rheumatology and may involve a multitude of organs. Amidst the central nervous system (CNS) presentation, involvement of spinal cord is rarer still.  Case Report: A 50-year-old male came with chief complaints of tingling sensation over both soles since 2 months associated with lower back ache and gait disturbance in the form of spastic gait. X-rays of spine were suggestive of a growth at the level of D10\u2013D12 compressing the spinal cord with no focal sclerotic\/lytic lesions, and MRI dorsolumbar spine showed dural tail sign. The patient underwent excision of dural mass, and histopathology revealed majority of plasma cells positive for IgG4. Case 2: A 65-year-old female came with complaints of cough, shortness of breath, and fever on and off since 2 months. No history of hemoptysis, purulent sputum, weight loss. On examination: There were bilateral rhonchi in the left upper zone. MRI spine showed focal erosion with soft-tissue thickening at the right paravertebral region extending from D5-9. The patient underwent surgery (fusion D6-8 and ostectomy D7 posterior rib resection D7 right side) with the right pleural biopsy and transpendicular intracorporal biopsy D7. Histopathology was compatible with findings of IgG4 disease.  Discussion: IgG4 tumors presenting in CNS itself is rare and rarer in spinal cord. Histopathological examination is central to diagnose and prognosticate the disease further as IgG4-related disease manifestations may recur without proper treatment.  Keywords: IgG4, spinal mass, central nervous system, pleura.<\/jats:p>","DOI":"10.13107\/jocr.2023.v13.i04.3606","type":"journal-article","created":{"date-parts":[[2023,5,3]],"date-time":"2023-05-03T06:06:49Z","timestamp":1683094009000},"page":"37-40","source":"Crossref","is-referenced-by-count":2,"title":["Mass: The Conundrum in Spine"],"prefix":"10.13107","volume":"13","author":[{"given":"P D","family":"Rath","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sunil","family":"Katoch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abhijeet Kumar","family":"Agrawal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Swetal","family":"Chouhan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H N","family":"Bajaj","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rahul","family":"Bisaralli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"5271","published-online":{"date-parts":[[2023]]},"container-title":["Journal of Orthopaedic Case Reports"],"original-title":[],"deposited":{"date-parts":[[2023,5,3]],"date-time":"2023-05-03T06:06:59Z","timestamp":1683094019000},"score":1,"resource":{"primary":{"URL":"https:\/\/jocr.co.in\/wp\/2023\/04\/10\/mass-the-conundrum-in-spine\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023]]},"references-count":0,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2023]]},"published-print":{"date-parts":[[2023]]}},"URL":"https:\/\/doi.org\/10.13107\/jocr.2023.v13.i04.3606","relation":{},"ISSN":["2250-0685","2321-3817"],"issn-type":[{"value":"2250-0685","type":"print"},{"value":"2321-3817","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023]]}}}