{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T14:20:27Z","timestamp":1778768427114,"version":"3.51.4"},"reference-count":0,"publisher":"Indian Orthopaedic Research Group","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Jocr"],"published-print":{"date-parts":[[2026]]},"abstract":"<jats:p>Introduction: Hip fracture surgery is frequently associated with severe post-operative pain, traditionally managed using opioid-based regimens. In elderly patients, opioids are linked to adverse effects such as delirium, respiratory depression, and delayed mobilization. Opioid-sparing multimodal analgesia, incorporating non-opioid medications and regional anesthesia techniques, has emerged as a promising alternative. This study aimed to compare the efficacy and safety of an opioid-sparing multimodal analgesia regimen with standard opioid-based analgesia in patients undergoing hip fracture surgery.\n\nMaterials and Methods: This prospective randomized controlled trial enrolled 50 patients aged \u226550 years undergoing operative management for hip fractures. Participants were randomized into two groups: Group M (multimodal analgesia, n = 25) and Group S (standard opioid-based analgesia, n = 25). Group M received scheduled non-opioid analgesics and a regional nerve block with opioids reserved for rescue, while Group S received conventional opioid-centered pain management. Post-operative pain was assessed using the Visual Analog Scale (VAS) at 2, 6, 12, 24, and 48 h. Total opioid consumption within 48 h, opioid-related adverse effects, incidence of delirium, time to first mobilization, length of hospital stay, and patient satisfaction were recorded.\n\nResults: Baseline characteristics were comparable between groups. Group M demonstrated significantly lower VAS scores at all time points (e.g., 24 h: 2.2 \u00b1 0.6 vs. 3.4 \u00b1 0.8; P &lt; 0.001) and reduced 48-h opioid consumption (9.6 \u00b1 3.2 mg vs. 22.8 \u00b1 5.6 mg; P &lt; 0.001). Opioid-related adverse effects and post-operative delirium were significantly lower in Group M (12% vs. 36%; P = 0.04). Patients in Group M achieved earlier mobilization (27.4 \u00b1 6.8 vs. 39.6 \u00b1 9.2 h; P &lt; 0.001) and had shorter hospital stays (6.1 \u00b1 1.4 vs. 8.3 \u00b1 2.0 days; P &lt; 0.001). Patient satisfaction was higher in the multimodal group.\n\nConclusion: Opioid-sparing multimodal analgesia provides superior pain control with reduced opioid consumption and improved post-operative outcomes compared with standard analgesia in hip fracture surgery. Its routine adoption may enhance recovery and safety in this high-risk population.\n\nKeywords: Hip fracture surgery, multimodal analgesia, opioid-sparing, post-operative pain, randomized controlled trial.<\/jats:p>","DOI":"10.13107\/jocr.2026.v16.i05.7322","type":"journal-article","created":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T13:55:10Z","timestamp":1778766910000},"page":"432-439","source":"Crossref","is-referenced-by-count":0,"title":["Opioid-Sparing Multimodal Analgesia versus Standard Analgesia in Hip Fracture Surgery: A Prospective Study"],"prefix":"10.13107","volume":"16","author":[{"given":"Shubham","family":"Pandoh","sequence":"first","affiliation":[{"name":"Department of Orthopaedics, Government Medical College and Hospital, Jammu and Kashmir, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bhat Jameel Mohd","family":"Jabbar","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Government Medical College and Hospital, Jammu and Kashmir, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sukhil","family":"Raina","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Government Medical College and Hospital, Jammu and Kashmir, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Priya","family":"Ramalingam","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia, Rajiv Gandhi Cooperative Hospital, Palakkad, Kerala, India,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gopal","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia, Dr. Rajendra Prasad Government Medical College, Sadarpur, Himachal Pradesh, India,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ketan","family":"Rupala","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, SGT Medical College, Gurugram, Haryana, India."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"5271","published-online":{"date-parts":[[2026]]},"container-title":["Journal of Orthopaedic Case Reports"],"original-title":[],"deposited":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T13:55:12Z","timestamp":1778766912000},"score":1,"resource":{"primary":{"URL":"https:\/\/jocr.co.in\/wp\/2026\/05\/opioid-sparing-multimodal-analgesia-versus-standard-analgesia-in-hip-fracture-surgery-a-prospective-study\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":0,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2026]]},"published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.13107\/jocr.2026.v16.i05.7322","relation":{},"ISSN":["2321-3817"],"issn-type":[{"value":"2321-3817","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]}}}