{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T09:05:18Z","timestamp":1789290318718,"version":"build-2803163510"},"reference-count":0,"publisher":"Indian Orthopaedic Research Group","issue":"8","content-domain":{"domain":["jocr.co.in"],"crossmark-restriction":true},"short-container-title":["Jocr"],"published-print":{"date-parts":[[2026]]},"abstract":"<jats:p>Aims and Background: Femoral neck fractures remain a major challenge in orthopedic trauma because the tenuous intracapsular blood supply predisposes to non-union and avascular necrosis even after mechanically sound fixation. Internal fixation is the standard head-preserving option in younger adults, yet biological failure persists. This study aimed to determine whether supplementing conventional osteosynthesis with autologous platelet-rich plasma (PRP) accelerates bone healing and improves functional recovery.\n\nMaterials and Methods: In this prospective comparative study, 60 patients aged 18\u201360 years with acute femoral neck fractures were allocated equally to two groups. Group A (n = 30) underwent closed reduction and internal fixation with three cannulated cancellous screws augmented by intraoperative PRP injection through the screw cannulations; Group B (n = 30) received identical screw fixation alone. The groups were comparable in demographics, injury mechanism, and Garden and Pauwels classifications. Outcomes assessed over a minimum 1-year follow-up were time to radiological union, time to full weight-bearing, functional recovery by the Harris Hip Score (HHS), pain by the Visual Analog Scale (VAS), and post-operative complications.\n\nResults: PRP augmentation significantly accelerated healing. Radiological union was achieved at a mean of 3.54 \u00b1 0.32 months in Group A versus 4.03 \u00b1 0.47 months in Group B (P &lt; 0.0001), permitting earlier full weight-bearing (3.58 \u00b1 0.39 vs. 4.19 \u00b1 0.54 months; P &lt; 0.0001). The PRP group reached a higher final mean HHS (91.03 \u00b1 1.38 vs. 88.73 \u00b1 2.18; P &lt; 0.0001). Final VAS scores did not differ significantly between groups (4.43 \u00b1 0.50 vs. 4.70 \u00b1 0.70; P = 0.09). Complication, non-union, and avascular necrosis rates requiring revision were low and comparable between groups.\n\nConclusion: Autologous PRP is a safe and effective biological adjunct to internal fixation of femoral neck fractures. It shortens the time to union and to full weight-bearing and improves functional hip recovery without increasing surgical complications, and merits consideration as a routine addition to head-preserving osteosynthesis.\n\nKeywords: Femoral neck fracture, platelet-rich plasma, osteosynthesis, fracture healing, Harris hip score.<\/jats:p>","DOI":"10.13107\/jocr.2026.v16.i08.7906","type":"journal-article","created":{"date-parts":[[2026,8,8]],"date-time":"2026-08-08T11:25:41Z","timestamp":1786188341000},"page":"393-399","update-policy":"https:\/\/doi.org\/10.13107\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Platelet-Rich Plasma Augmentation of Osteosynthesis in Femoral Neck Fractures: A Prospective Comparative Study Demonstrating Accelerated Union and Improved Function"],"prefix":"10.13107","volume":"16","author":[{"given":"Adarsh","family":"Baiwal","sequence":"first","affiliation":[{"name":"Department of Orthopaedics, Gandhi Medical College and Associated Hamidia Hospital, Bhopal, Madhya Pradesh, India."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saurav","family":"Mukhopadhyay","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Gandhi Medical College and Associated Hamidia Hospital, Bhopal, Madhya Pradesh, India."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Utkarsh","family":"Mittal","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Gandhi Medical College and Associated Hamidia Hospital, Bhopal, Madhya Pradesh, India."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anurag","family":"Tiwari","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Gandhi Medical College and Associated Hamidia Hospital, Bhopal, Madhya Pradesh, India."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashish","family":"Gohiya","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Gandhi Medical College and Associated Hamidia Hospital, Bhopal, Madhya Pradesh, India."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"5271","published-online":{"date-parts":[[2026]]},"container-title":["Journal of Orthopaedic Case Reports"],"original-title":[],"deposited":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T08:45:26Z","timestamp":1789289126000},"score":1,"resource":{"primary":{"URL":"https:\/\/jocr.co.in\/wp\/2026\/08\/platelet-rich-plasma-augmentation-of-osteosynthesis-in-femoral-neck-fractures-a-prospective-comparative-study-demonstrating-accelerated-union-and-improved-function\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":0,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2026]]},"published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.13107\/jocr.2026.v16.i08.7906","relation":{},"ISSN":["2321-3817"],"issn-type":[{"value":"2321-3817","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]},"assertion":[{"value":"Research Article","name":"content_type","label":"Content Type"},{"value":"Yes","name":"crosschecked","label":"CrossChecked"},{"value":"Yes","name":"peer_reviewed","label":"Peer Reviewed"},{"value":"10.13107\/jocr.2026.v16.i08.7906","name":"published","label":"Published"},{"value":"Creative Commons Attribution","name":"license","label":"License","explanation":{"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},"group":{"name":"rights","label":"Rights"}}]}}