{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T22:58:28Z","timestamp":1777417108832,"version":"3.51.4"},"reference-count":12,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2000,4,1]],"date-time":"2000-04-01T00:00:00Z","timestamp":954547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ann Pharmacother"],"published-print":{"date-parts":[[2000,4]]},"abstract":"<jats:sec>\n                    <jats:title>OBJECTIVE:<\/jats:title>\n                    <jats:p>To evaluate the management strategies available for the complications associated with bacillus Calmette\u2013Gu\u00e9rin (BCG) immunotherapy in the treatment of bladder cancer.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>DATA SOURCES:<\/jats:title>\n                    <jats:p>Clinical literature accessed through MEDLINE (January 1983\u2013January 1999). Key search terms included bacillus Calmette-Gu\u00e9rin, BCG, and bladder cancer.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>DATA SYNTHESIS:<\/jats:title>\n                    <jats:p>BCG vaccine is a live-attenuated strain of Mycobacterium bovis; therefore, the risk for complications exists. An evaluation of treatment regimens was conducted, and the management strategies are presented.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS:<\/jats:title>\n                    <jats:p>The complications associated with BCG immunotherapy range from local reactions to potentially fatal systemic reactions requiring long-term therapy. Therefore, healthcare practitioners need to be aware of the current treatment regimens available.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1345\/aph.19145","type":"journal-article","created":{"date-parts":[[2003,6,3]],"date-time":"2003-06-03T16:37:57Z","timestamp":1054658277000},"page":"529-532","source":"Crossref","is-referenced-by-count":15,"title":["Management of Complications of Bacillus Calmette\u2013Gu\u00e9rin Immunotherapy in the Treatment of Bladder Cancer"],"prefix":"10.1177","volume":"34","author":[{"given":"Tammy C","family":"Huang","sequence":"first","affiliation":[{"name":"Tammy C Huang PharmD, at time of writing, PharmD Student, College of Pharmacy, University of Michigan, Ann Arbor, MI; now, Pharmacy Resident, Lucile Packard Children's Hospital at Stanford, 725 Welch Rd., Palo Alto, CA 94304, FAX 650\/497-8972"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2000,4,1]]},"reference":[{"key":"bibr1-aph.19145","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.1998.545"},{"key":"bibr2-aph.19145","doi-asserted-by":"publisher","DOI":"10.1159\/000475135"},{"key":"bibr3-aph.19145","doi-asserted-by":"publisher","DOI":"10.1159\/000471561"},{"key":"bibr4-aph.19145","first-page":"695","volume":"20","author":"Sosnowski JT","year":"1994","journal-title":"Compr Ther"},{"key":"bibr5-aph.19145","doi-asserted-by":"publisher","DOI":"10.1002\/jps.2600820602"},{"key":"bibr6-aph.19145","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)37316-0"},{"key":"bibr7-aph.19145","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-2197.1998.tb04768.x"},{"key":"bibr8-aph.19145","doi-asserted-by":"publisher","DOI":"10.1159\/000474920"},{"key":"bibr9-aph.19145","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(01)64936-X"},{"key":"bibr10-aph.19145","first-page":"84","volume":"1","author":"Grange JM","year":"1998","journal-title":"Commun Dis Public Health"},{"key":"bibr11-aph.19145","first-page":"1112","volume":"88","author":"Proctor DD","year":"1993","journal-title":"Am J Gastroenterol"},{"key":"bibr12-aph.19145","doi-asserted-by":"publisher","DOI":"10.1007\/BF00190319"}],"container-title":["Annals of Pharmacotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1345\/aph.19145","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1345\/aph.19145","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T11:03:16Z","timestamp":1777374196000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1345\/aph.19145"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,4]]},"references-count":12,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2000,4]]}},"alternative-id":["10.1345\/aph.19145"],"URL":"https:\/\/doi.org\/10.1345\/aph.19145","relation":{},"ISSN":["1060-0280","1542-6270"],"issn-type":[{"value":"1060-0280","type":"print"},{"value":"1542-6270","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,4]]}}}