{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T14:45:33Z","timestamp":1787064333492,"version":"build-2736575974"},"reference-count":23,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2002,1,1]],"date-time":"2002-01-01T00:00:00Z","timestamp":1009843200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ann Pharmacother"],"published-print":{"date-parts":[[2002,1]]},"abstract":"<jats:sec>\n                    <jats:title>OBJECTIVE:<\/jats:title>\n                    <jats:p>To document the first successful treatment of a patient with Hansenula anomala pneumonia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CASE SUMMARY:<\/jats:title>\n                    <jats:p>A healthy 32-year-old white man who underwent splenectomy and aortic repair following a motor vehicle accident developed a life-threatening infection 2 days after admission into the intensive care unit (ICU). A rare fungus, H. anomala, was isolated from his lungs, blood, and urine. Lipid complex amphotericin B (ABLC) was initiated following worsening signs of infection complicated by renal failure. The patient received ABLC for 17 days, eventually making a full recovery, allowing ICU discharge 1 month after admission.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>DISCUSSION:<\/jats:title>\n                    <jats:p>This case represents the first successful treatment of H. anomala pneumonia reported in the literature. H. anomala infections typically occur in immunocompromised, neonatal, or pediatric populations in extrapulmonary sites. All 6 cases of H. anomala pneumonia reported in the literature were fatal, and all preceded the availability of ABLC. This case of H. anomala pneumonia is unique because our adult patient survived possibly due to the availability of aggressive treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS:<\/jats:title>\n                    <jats:p>ABLC may be the agent of choice for treatment of H. anomala infections, particularly in patients with acute renal failure.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1345\/aph.1a192","type":"journal-article","created":{"date-parts":[[2003,6,4]],"date-time":"2003-06-04T15:59:15Z","timestamp":1054742355000},"page":"59-62","source":"Crossref","is-referenced-by-count":7,"title":["Amphotericin B Lipid Complex for\n                    <i>Hansenula Anomala<\/i>\n                    Pneumonia"],"prefix":"10.1177","volume":"36","author":[{"given":"Sandra L","family":"Kane","sequence":"first","affiliation":[{"name":"Sandra L Kane PharmD MSc, at time of writing, Critical Care Pharmacy Fellow, College of Pharmacy, The Ohio State University, Columbus, OH; now, Assistant Professor, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph F","family":"Dasta","sequence":"additional","affiliation":[{"name":"Joseph F Dasta MSc FCCM, Professor of Pharmacy, College of Pharmacy, The Ohio State University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles H","family":"Cook","sequence":"additional","affiliation":[{"name":"Charles H Cook MD, Assistant Professor, Department of Surgery, College of Medicine and Public Health, The Ohio State University"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2002,1,1]]},"reference":[{"key":"bibr-bibr1-aph.1A192","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1995.00430110089009"},{"key":"bibr-bibr2-aph.1A192","first-page":"1946","volume-title":"Infectious diseases","author":"Shadomy S","year":"1997"},{"key":"bibr-bibr3-aph.1A192","first-page":"179","volume":"2","author":"Csillag A","year":"1954","journal-title":"Acta Microbiol Hung"},{"key":"bibr-bibr4-aph.1A192","first-page":"299","volume":"9","author":"Wang CJK","year":"1958","journal-title":"Mycopathologia"},{"key":"bibr-bibr5-aph.1A192","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1988.00380050214030"},{"key":"bibr-bibr6-aph.1A192","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0507.1992.tb00883.x"},{"key":"bibr-bibr7-aph.1A192","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(86)90827-5"},{"key":"bibr-bibr8-aph.1A192","first-page":"541","volume":"86","author":"Milstoc M","year":"1986","journal-title":"NY State J Med"},{"key":"bibr-bibr9-aph.1A192","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(87)90400-1"},{"key":"bibr-bibr10-aph.1A192","first-page":"752","volume":"31","author":"Kostiala I","year":"1982","journal-title":"Curr Ther Res"},{"key":"bibr-bibr11-aph.1A192","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/10.6.1182"},{"key":"bibr-bibr12-aph.1A192","doi-asserted-by":"publisher","DOI":"10.1007\/BF00436934"},{"key":"bibr-bibr13-aph.1A192","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/11.3.507"},{"key":"bibr-bibr14-aph.1A192","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1989.00390030151034"},{"key":"bibr-bibr15-aph.1A192","doi-asserted-by":"publisher","DOI":"10.1097\/00006454-199105000-00010"},{"key":"bibr-bibr16-aph.1A192","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0507.1991.tb00670.x"},{"key":"bibr-bibr17-aph.1A192","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.31.622"},{"key":"bibr-bibr18-aph.1A192","doi-asserted-by":"publisher","DOI":"10.1007\/BF00144819"},{"key":"bibr-bibr19-aph.1A192","doi-asserted-by":"publisher","DOI":"10.1097\/00006454-199402000-00018"},{"key":"bibr-bibr20-aph.1A192","first-page":"995","volume":"14","author":"Goss G","year":"1994","journal-title":"Bone Marrow Transplant"},{"key":"bibr-bibr21-aph.1A192","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0507.1997.tb00213.x"},{"key":"bibr-bibr22-aph.1A192","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/41.3.373"},{"key":"bibr-bibr23-aph.1A192","first-page":"267","volume":"33","author":"Ma JS","year":"2000","journal-title":"J Microbiol Immunol Infect"}],"container-title":["Annals of Pharmacotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1345\/aph.1A192","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1345\/aph.1A192","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T11:05:15Z","timestamp":1777374315000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1345\/aph.1A192"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,1]]},"references-count":23,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2002,1]]}},"alternative-id":["10.1345\/aph.1A192"],"URL":"https:\/\/doi.org\/10.1345\/aph.1a192","relation":{},"ISSN":["1060-0280","1542-6270"],"issn-type":[{"value":"1060-0280","type":"print"},{"value":"1542-6270","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002,1]]}}}