{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T10:12:12Z","timestamp":1792059132617,"version":"4.4.0"},"reference-count":18,"publisher":"SAGE Publications","issue":"11","license":[{"start":{"date-parts":[[2002,11,1]],"date-time":"2002-11-01T00:00:00Z","timestamp":1036108800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ann Pharmacother"],"published-print":{"date-parts":[[2002,11]]},"abstract":"<jats:sec>\n                    <jats:title>OBJECTIVE:<\/jats:title>\n                    <jats:p>To review the efficacy and safety of various drug treatments for sialorrhea. Pharmacotherapy for drug-induced sialorrhea is not addressed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>DATA SOURCES:<\/jats:title>\n                    <jats:p>Clinical studies were identified using PubMed (1966\u2013October 2001). Key search terms included sialorrhea and drug therapy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>DATA SYNTHESIS:<\/jats:title>\n                    <jats:p>Sialorrhea is a social and physical detriment to patients. Drug treatment, although not necessarily the treatment of choice for all patients, can offer some symptom relief.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS:<\/jats:title>\n                    <jats:p>Literature has documented that benztropine, glycopyrrolate, and scopolamine can reduce the incidence of sialorrhea. Although the literature evaluating the therapeutic options has limitations (e.g., small sample size, inconsistent outcome measurements), glycopyrrolate may have an advantage over the other agents due to fewer adverse effects.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1345\/aph.1c019","type":"journal-article","created":{"date-parts":[[2003,6,4]],"date-time":"2003-06-04T16:10:01Z","timestamp":1054743001000},"page":"1785-1790","source":"Crossref","is-referenced-by-count":43,"title":["Sialorrhea \u2014 Therapeutic Drug Options"],"prefix":"10.1177","volume":"36","author":[{"given":"Dorothy Z","family":"Tscheng","sequence":"first","affiliation":[{"name":"Dorothy Z Tscheng BScPhm, Drug Information Pharmacist, Drug Information and Research Centre, Ontario Pharmacists' Association, Don Mills, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2002,11,1]]},"reference":[{"key":"bibr-bibr1-aph.1C019","doi-asserted-by":"publisher","DOI":"10.1001\/archpedi.1996.02170340046009"},{"key":"bibr-bibr2-aph.1C019","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.54.1.244"},{"key":"bibr-bibr3-aph.1C019","doi-asserted-by":"publisher","DOI":"10.1001\/archpedi.154.12.1214"},{"key":"bibr-bibr4-aph.1C019","doi-asserted-by":"publisher","DOI":"10.1345\/aph.19259"},{"key":"bibr-bibr5-aph.1C019","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8749.1996.tb15063.x"},{"key":"bibr-bibr6-aph.1C019","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2842.2000.00575.x"},{"key":"bibr-bibr7-aph.1C019","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8749.1989.tb04000.x"},{"key":"bibr-bibr8-aph.1C019","doi-asserted-by":"publisher","DOI":"10.1177\/000992289803700805"},{"key":"bibr-bibr9-aph.1C019","first-page":"198","volume-title":"ADA guide to dental therapeutics","author":"Yagiela JA","year":"2000","edition":"2"},{"key":"bibr-bibr10-aph.1C019","doi-asserted-by":"publisher","DOI":"10.1017\/S0012162201000718"},{"key":"bibr-bibr11-aph.1C019","doi-asserted-by":"publisher","DOI":"10.1016\/0022-510X(96)00104-9"},{"key":"bibr-bibr12-aph.1C019","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.67.5.697"},{"key":"bibr-bibr13-aph.1C019","unstructured":"Gillis MC, ed. 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