{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T23:27:13Z","timestamp":1777418833822,"version":"3.51.4"},"reference-count":22,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2004,6,1]],"date-time":"2004-06-01T00:00:00Z","timestamp":1086048000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ann Pharmacother"],"published-print":{"date-parts":[[2004,6]]},"abstract":"<jats:sec>\n                    <jats:title>OBJECTIVE:<\/jats:title>\n                    <jats:p>To evaluate the relative safety and efficacy of finasteride for treatment of hirsutism related to hyperandrogenism in women.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>DATA SOURCES:<\/jats:title>\n                    <jats:p>Literature retrieval was accessed through MEDLINE (1966-March 2003) using the terms finasteride and hirsutism. Additional information was obtained from the drug manufacturer.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>DATA SYNTHESIS:<\/jats:title>\n                    <jats:p>Finasteride has been evaluated for treatment of hirsutism in multiple observational and randomized trials. Finasteride lowered hirsutism scores by 30\u201360% in most trials, as well as decreasing average hair diameter. In comparative trials, finasteride demonstrated efficacy similar to that of other antiandrogens, with fewer adverse effects.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS:<\/jats:title>\n                    <jats:p>Finasteride does reduce the overall hair diameter and number in androgen-sensitive areas. Reported adverse effects have been minimal. Concern over potential teratogenicity and lack of long-term safety information leave finasteride a secondary treatment option for hirsutism.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1345\/aph.1d461","type":"journal-article","created":{"date-parts":[[2004,4,26]],"date-time":"2004-04-26T20:13:20Z","timestamp":1083010400000},"page":"1070-1073","source":"Crossref","is-referenced-by-count":24,"title":["Relative Safety and Efficacy of Finasteride for Treatment of Hirsutism"],"prefix":"10.1177","volume":"38","author":[{"given":"Kara A","family":"Townsend","sequence":"first","affiliation":[{"name":"Kara A Townsend PharmD, Assistant Clinical Professor, Auburn University, Harrison School of Pharmacy; Adjunct Assistant Professor, Department of Family Practice, University of South Alabama, Mobile, AL"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karen F","family":"Marlowe","sequence":"additional","affiliation":[{"name":"Karen F Marlowe PharmD BCPS, Assistant Clinical Professor, Auburn University, Harrison School of Pharmacy; Adjunct Assistant Professor, Department of Internal Medicine, University of South Alabama"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2004,6,1]]},"reference":[{"key":"bibr1-aph.1D461","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(64)92789-8"},{"key":"bibr2-aph.1D461","first-page":"995","volume":"101","author":"Azziz R","year":"2003","journal-title":"Obstet Gynecol"},{"key":"bibr3-aph.1D461","doi-asserted-by":"publisher","DOI":"10.1055\/s-0029-1212097"},{"key":"bibr4-aph.1D461","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1998.tb10197.x"},{"key":"bibr5-aph.1D461","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(81)90746-8"},{"key":"bibr6-aph.1D461","doi-asserted-by":"publisher","DOI":"10.1097\/00001703-199510000-00004"},{"key":"bibr7-aph.1D461","doi-asserted-by":"publisher","DOI":"10.1016\/S0733-8635(18)30283-3"},{"key":"bibr8-aph.1D461","first-page":"831","volume":"79","author":"Fruzzetti F","year":"1994","journal-title":"J Clin Endocrinol Metab"},{"key":"bibr9-aph.1D461","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(16)58627-0"},{"key":"bibr10-aph.1D461","doi-asserted-by":"publisher","DOI":"10.4158\/EP.7.1.5"},{"key":"bibr11-aph.1D461","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(16)58388-5"},{"key":"bibr12-aph.1D461","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(16)57727-9"},{"key":"bibr13-aph.1D461","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(00)00600-2"},{"key":"bibr14-aph.1D461","doi-asserted-by":"publisher","DOI":"10.1007\/BF03350800"},{"key":"bibr15-aph.1D461","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(99)00633-0"},{"key":"bibr16-aph.1D461","first-page":"89","volume":"85","author":"Moghetti P","year":"2000","journal-title":"J Clin Endocrinol Metab"},{"key":"bibr17-aph.1D461","doi-asserted-by":"publisher","DOI":"10.1210\/jcem.84.4.5591"},{"key":"bibr18-aph.1D461","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(02)04927-0"},{"key":"bibr19-aph.1D461","doi-asserted-by":"publisher","DOI":"10.1530\/eje.0.1410361"},{"key":"bibr20-aph.1D461","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(00)00470-2"},{"key":"bibr21-aph.1D461","first-page":"203","volume":"27","author":"Bayhan G","year":"2000","journal-title":"Clin Exp Obstet Gynecol"},{"key":"bibr22-aph.1D461","volume-title":"Package insert. 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