{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T23:26:29Z","timestamp":1777418789673,"version":"3.51.4"},"reference-count":20,"publisher":"SAGE Publications","issue":"10","license":[{"start":{"date-parts":[[2004,10,1]],"date-time":"2004-10-01T00:00:00Z","timestamp":1096588800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ann Pharmacother"],"published-print":{"date-parts":[[2004,10]]},"abstract":"<jats:sec>\n                    <jats:title>OBJECTIVE<\/jats:title>\n                    <jats:p>To review the literature for treatment of migraine headaches with sumatriptan during pregnancy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>DATA SOURCES<\/jats:title>\n                    <jats:p>Studies and reports were located in International Pharmaceutical Abstracts (1970-September 2003) and MEDLINE (1966-week 3 September 2003).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>DATA SYNTHESIS<\/jats:title>\n                    <jats:p>Research has been performed to evaluate the risk of teratogenesis after sumatriptan exposure in pregnant patients. Data have been collected in areas including placental transmission of sumatriptan, prospective pregnancy registries, open-labeled and controlled prospective studies, and a retrospective prescription-linked study. As of August 6, 2004, no randomized controlled trials have been conducted with exposure to sumatriptan during pregnancy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS<\/jats:title>\n                    <jats:p>Teratogenesis occurs in approximately 150 000 births per year which represents an incidence of 3\u20135%. Available literature to date indicates that exposure to sumatriptan during pregnancy has no additional risk of birth defects compared with the incidence in the general population.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1345\/aph.1d586","type":"journal-article","created":{"date-parts":[[2004,8,17]],"date-time":"2004-08-17T21:01:12Z","timestamp":1092776472000},"page":"1726-1730","source":"Crossref","is-referenced-by-count":20,"title":["Treatment of Migraine Headaches with Sumatriptan in Pregnancy"],"prefix":"10.1177","volume":"38","author":[{"given":"Michelle L","family":"Hilaire","sequence":"first","affiliation":[{"name":"Michelle L Hilaire PharmD, Primary Care Specialty Resident, University of Tennessee Family Practice Center, Memphis, TN"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L Brian","family":"Cross","sequence":"additional","affiliation":[{"name":"L Brian Cross PharmD CDE, Assistant Professor, Colleges of Pharmacy and Medicine, University of Tennessee; University of Tennessee Family Practice Center"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samantha F","family":"Eichner","sequence":"additional","affiliation":[{"name":"Samantha F Eichner PharmD, Assistant Professor, College of Pharmacy, University of Tennessee; University of Tennessee Health Science Center, Memphis"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2004,10,1]]},"reference":[{"key":"bibr1-aph.1D586","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.48.3_Suppl_3.4S"},{"issue":"6","key":"bibr2-aph.1D586","first-page":"S17","volume":"44","author":"Stewart WF","year":"1994","journal-title":"Neurology"},{"key":"bibr3-aph.1D586","doi-asserted-by":"publisher","DOI":"10.1046\/j.1526-4610.2003.03005.x"},{"key":"bibr4-aph.1D586","doi-asserted-by":"publisher","DOI":"10.1046\/j.1468-2982.2003.00480.x"},{"key":"bibr5-aph.1D586","doi-asserted-by":"publisher","DOI":"10.1046\/j.1468-2982.1997.1707765.x"},{"key":"bibr6-aph.1D586","first-page":"383","volume":"19","author":"Pfaffenrath V","year":"1998","journal-title":"What are the safest treatment options? Drug Saf"},{"key":"bibr7-aph.1D586","doi-asserted-by":"publisher","DOI":"10.1097\/00006254-200203000-00023"},{"key":"bibr8-aph.1D586","doi-asserted-by":"publisher","DOI":"10.1016\/0029-7844(95)00288-3"},{"key":"bibr9-aph.1D586","doi-asserted-by":"publisher","DOI":"10.1097\/00006250-200008000-00016"},{"key":"bibr10-aph.1D586","unstructured":"10. Massiou H, Pitei D, Poole PH, Sikes C. Efficacy of eletriptan for the treatment of migraine in women with menstrually associated migraine, and in women on contraceptives or hormone replacement therapy: meta-analyses of randomized clinical trials (poster). Presented at: Headache World 2000, London, September 3\u20137, 2000."},{"key":"bibr11-aph.1D586","doi-asserted-by":"publisher","DOI":"10.1046\/j.1526-4610.2001.111006248.x"},{"key":"bibr12-aph.1D586","doi-asserted-by":"publisher","DOI":"10.2165\/00002018-200326020-00003"},{"key":"bibr13-aph.1D586","volume-title":"Drugs in pregnancy and lactation","author":"Briggs G","year":"2002","edition":"6"},{"key":"bibr14-aph.1D586","doi-asserted-by":"publisher","DOI":"10.3181\/00379727-210-43941"},{"key":"bibr15-aph.1D586","doi-asserted-by":"publisher","DOI":"10.1046\/j.1526-4610.2001.111006351.x"},{"key":"bibr16-aph.1D586","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(00)70506-0"},{"key":"bibr17-aph.1D586","doi-asserted-by":"publisher","DOI":"10.1007\/s004040050252"},{"key":"bibr18-aph.1D586","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.51.2.581"},{"key":"bibr19-aph.1D586","doi-asserted-by":"publisher","DOI":"10.1046\/j.1526-4610.2000.00003.x"},{"key":"bibr20-aph.1D586","unstructured":"20. 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