{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T23:43:08Z","timestamp":1777419788566,"version":"3.51.4"},"reference-count":9,"publisher":"SAGE Publications","issue":"11","license":[{"start":{"date-parts":[[2006,11,1]],"date-time":"2006-11-01T00:00:00Z","timestamp":1162339200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ann Pharmacother"],"published-print":{"date-parts":[[2006,11]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To report a case of psychosis induced by therapeutic doses of baclofen.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case Summary:<\/jats:title>\n                    <jats:p>A 32-year-old Hindu man was prescribed oral baclofen 10 mg twice daily for relief of muscular spasms secondary to tetanus. After 4 weeks of baclofen use, he presented to the psychiatry emergency facility with a 4 day history of third-person auditory hallucinations and persecutory and referential delusions without underlying mood symptoms. These symptoms resolved within 1 week of discontinuing baclofen. Rechallenge with baclofen resulted in reemergence of psychotic symptoms, which disappeared after discontinuing baclofen.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion:<\/jats:title>\n                    <jats:p>Reemergence of psychotic symptoms after rechallenge with baclofen suggests baclofen-induced psychosis. Use of the Naranjo probability scale indicates a probable association of baclofen with this patient's psychosis. The absence of underlying mood disorder makes this case different from previously reported ones.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Baclofen may be associated with the occurrence of psychosis. Clinicians should consider baclofen-induced psychosis as a differential diagnosis in patients presenting with psychosis during treatment with this drug.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1345\/aph.1h202","type":"journal-article","created":{"date-parts":[[2006,10,17]],"date-time":"2006-10-17T23:33:34Z","timestamp":1161128014000},"page":"2071-2073","source":"Crossref","is-referenced-by-count":22,"title":["Baclofen-Induced Psychosis"],"prefix":"10.1177","volume":"40","author":[{"given":"Jatinder Mohan","family":"Chawla","sequence":"first","affiliation":[{"name":"Department of Psychiatry, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ravindra","family":"Rao","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, All India Institute of Medical Sciences"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajesh","family":"Sagar","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, All India Institute of Medical Sciences"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2006,11,1]]},"reference":[{"key":"bibr1-aph.1H202","first-page":"543","volume-title":"Goodman and Gilman's the pharmacological basis of therapeutics","author":"Standaert DG","year":"2005","edition":"11"},{"key":"bibr2-aph.1H202","doi-asserted-by":"publisher","DOI":"10.1038\/clpt.1981.154"},{"key":"bibr3-aph.1H202","doi-asserted-by":"publisher","DOI":"10.1176\/appi.psy.46.6.503"},{"key":"bibr4-aph.1H202","first-page":"389","volume":"61","author":"Chodorowski Z","year":"2004","journal-title":"Przegl Lek"},{"key":"bibr5-aph.1H202","first-page":"757","volume":"17","author":"Wolf ME","year":"1982","journal-title":"Biol Psychiatry"},{"key":"bibr6-aph.1H202","first-page":"318","volume":"49","author":"Yassa RY","year":"1988","journal-title":"J Clin Psychiatry"},{"issue":"5","key":"bibr7-aph.1H202","first-page":"18","volume":"48","author":"Pinto Ode S","year":"1972","journal-title":"Postgrad Med J"},{"key":"bibr8-aph.1H202","doi-asserted-by":"publisher","DOI":"10.1038\/sc.1986.45"},{"key":"bibr9-aph.1H202","first-page":"211","volume":"53","author":"Sommer BR","year":"1992","journal-title":"J Clin Psychiatry"}],"container-title":["Annals of Pharmacotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1345\/aph.1H202","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1345\/aph.1H202","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T11:11:39Z","timestamp":1777374699000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1345\/aph.1H202"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,11]]},"references-count":9,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2006,11]]}},"alternative-id":["10.1345\/aph.1H202"],"URL":"https:\/\/doi.org\/10.1345\/aph.1h202","relation":{},"ISSN":["1060-0280","1542-6270"],"issn-type":[{"value":"1060-0280","type":"print"},{"value":"1542-6270","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,11]]}}}