{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T17:30:35Z","timestamp":1763746235389,"version":"3.38.0"},"reference-count":13,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[1999,1,1]],"date-time":"1999-01-01T00:00:00Z","timestamp":915148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vet Pathol"],"published-print":{"date-parts":[[1999,1]]},"abstract":"<jats:p> Melanomas are the most frequent malignant neoplasms of the oral cavity of dogs. Osteogenic melanoma is a rare variant of melanoma that has been described in humans but not in animals. We describe a case of malignant melanoma with bone production affecting the gingiva of a 12-year-old Miniature Dachshund dog. The tumor was a round, lightly pigmented mass that measured 1 cm in diameter and was hard to cut. Histologically, the tumor was composed of nests and lobules of anaplastic, round, melanin-containing cells supported by a stroma displaying abundant osteoid matrix. Many of the neoplastic melanocytic cells were in close contact with the osteoid trabeculae. Immunohistochemical tests revealed that the neoplastic cells were immunoreactive for S-100 and vimentin and showed no staining with cytokeratin. The animal had a local recurrence of the tumor 3 months after the initial excision. This is the first case of malignant melanoma with osteoid formation reported in animals. <\/jats:p>","DOI":"10.1354\/vp.36-1-74","type":"journal-article","created":{"date-parts":[[2003,4,24]],"date-time":"2003-04-24T20:12:40Z","timestamp":1051215160000},"page":"74-76","source":"Crossref","is-referenced-by-count":25,"title":["Oral Malignant Melanoma with Osteoid Formation in a Dog"],"prefix":"10.1177","volume":"36","author":[{"given":"S.","family":"Ch\u00e9nier","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Dor\u00e9","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1999,1,1]]},"reference":[{"key":"bibr1-vp.36-1-74","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)71766-1"},{"key":"bibr2-vp.36-1-74","doi-asserted-by":"publisher","DOI":"10.3109\/03008209009152417"},{"key":"bibr3-vp.36-1-74","first-page":"27","volume-title":"Pathology of Domestic Animals","volume":"2","author":"Barker IK","year":"1993","edition":"4"},{"key":"bibr4-vp.36-1-74","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0714.1993.tb01073.x"},{"key":"bibr5-vp.36-1-74","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.1992.427"},{"key":"bibr6-vp.36-1-74","doi-asserted-by":"publisher","DOI":"10.1016\/S0046-8177(83)80264-0"},{"key":"bibr7-vp.36-1-74","first-page":"666","volume":"120","author":"Haque S","year":"1996","journal-title":"Arch Pathol Lab Med"},{"key":"bibr8-vp.36-1-74","first-page":"398","volume-title":"Tumors in Domestic Animals","author":"Head KW","year":"1990","edition":"3"},{"key":"bibr9-vp.36-1-74","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199304000-00011"},{"key":"bibr10-vp.36-1-74","doi-asserted-by":"publisher","DOI":"10.1016\/S0046-8177(96)90389-5"},{"key":"bibr11-vp.36-1-74","first-page":"39","volume-title":"Bone Formation and Repair","author":"Trippel SB","year":"1994"},{"key":"bibr12-vp.36-1-74","first-page":"718","volume-title":"Pathology of Domestic Animals","volume":"1","author":"Wilcock BP","year":"1993","edition":"4"},{"key":"bibr13-vp.36-1-74","doi-asserted-by":"publisher","DOI":"10.1126\/science.3201241"}],"container-title":["Veterinary Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1354\/vp.36-1-74","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1354\/vp.36-1-74","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,3]],"date-time":"2025-03-03T01:04:02Z","timestamp":1740963842000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1354\/vp.36-1-74"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,1]]},"references-count":13,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1999,1]]}},"alternative-id":["10.1354\/vp.36-1-74"],"URL":"https:\/\/doi.org\/10.1354\/vp.36-1-74","relation":{},"ISSN":["0300-9858","1544-2217"],"issn-type":[{"type":"print","value":"0300-9858"},{"type":"electronic","value":"1544-2217"}],"subject":[],"published":{"date-parts":[[1999,1]]}}}