{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T16:20:39Z","timestamp":1759335639102,"version":"3.38.0"},"reference-count":38,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[1999,7,1]],"date-time":"1999-07-01T00:00:00Z","timestamp":930787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vet Pathol"],"published-print":{"date-parts":[[1999,7]]},"abstract":"<jats:p> In humans and dogs, bullous pemphigoid (BP) is an autoimmune blistering disease associated with the production of basement membrane autoantibodies that target the 180\u2013kd type XVII collagen (BP180, BPAG2) and\/or the 230-kd plakin epidermal isoform BPAGle (BP230). In two adult cats, an acquired dermatosis and stomatitis was diagnosed as BP subsequent to the fulfillment of the following criteria: 1) presence of cutaneous vesicles, erosions, and ulcers; 2) histologic demonstration of subepidermal vesiculation with inflammatory cells, including eosinophils; 3) in vivo deposition of IgG autoantibodies at the epidermal basement membrane zone; and 4) serum IgG autoantibodies targeting a 180-kd epidermal protein identified as type XVII collagen. In both cats, the antigenic epitopes targeted by IgG autoantibodies were shown to be situated in the NC16A ectodomain of type XVII collagen, a situation similar to that of humans and dogs with BP. Feline BP therefore can be considered a clinical, histopathologic, and immunologic homologue of BP in humans and dogs. <\/jats:p>","DOI":"10.1354\/vp.36-4-328","type":"journal-article","created":{"date-parts":[[2003,4,24]],"date-time":"2003-04-24T20:13:53Z","timestamp":1051215233000},"page":"328-335","source":"Crossref","is-referenced-by-count":30,"title":["Novel Feline Autoimmune Blistering Disease Resembling Bullous Pemphigoid in Humans: IgG Autoantibodies Target the NC16A Ectodomain of Type XVII Collagen (BP180\/BPAG2)"],"prefix":"10.1177","volume":"36","author":[{"given":"T.","family":"Olivry","sequence":"first","affiliation":[{"name":"Department of Companion Animal and Special Species, College of Veterinary Medicine, North Carolina State University, Raleigh, NC"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L. S.","family":"Chan","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Medical School, Northwestern University, Chicago, IL"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Medical School, Northwestern University, Chicago, IL"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Chace","sequence":"additional","affiliation":[{"name":"Old Canal Veterinary Clinic, Plainville, CT"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. 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