{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T08:29:37Z","timestamp":1770884977707,"version":"3.50.1"},"reference-count":18,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2000,9,1]],"date-time":"2000-09-01T00:00:00Z","timestamp":967766400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vet Pathol"],"published-print":{"date-parts":[[2000,9]]},"abstract":"<jats:p> Cryptosporidiosis is a common opportunistic infection in the gastrointestinal tract of human and nonhuman primates with AIDS. Pulmonary infection associated with Cryptosporidium spp. has not been previously reported in monkeys. Two macaques experimentally infected with simian immunodeficiency virus (SIV) had lesions containing cryptosporidial organisms involving the trachea, lungs, bile ducts, pancreas, and intestine. The pulmonary sections revealed moderate to severe bronchopneumonia associated with cryptosporidiosis. Numerous 2-4 \u03bcm oval Cryptosporidium spp. organisms were present in the cytoplasm of alveolar macrophages, multinucleated giant cells, and intestinal epithelial cells. Giant cells were positive for SIV by in situ hybridization. These are the first reported cases of cryptosporidiosis with involvement of pulmonary parenchyma in SIV-infected macaques. <\/jats:p>","DOI":"10.1354\/vp.37-5-472","type":"journal-article","created":{"date-parts":[[2003,4,24]],"date-time":"2003-04-24T20:16:47Z","timestamp":1051215407000},"page":"472-475","source":"Crossref","is-referenced-by-count":23,"title":["Pulmonary Cryptosporidiosis in Simian Immunodeficiency Virus\u2014infected Rhesus Macaques"],"prefix":"10.1177","volume":"37","author":[{"given":"T.","family":"Yanai","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L. V.","family":"Chalifoux","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K. G.","family":"Mansfield","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. A.","family":"Lackner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. A.","family":"Simon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2000,9,1]]},"reference":[{"key":"bibr1-vp.37-5-472","first-page":"2272","volume":"47","author":"Anderson BC","year":"1986","journal-title":"Am J Vet Res"},{"key":"bibr2-vp.37-5-472","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9975(08)80110-7"},{"key":"bibr3-vp.37-5-472","doi-asserted-by":"publisher","DOI":"10.1177\/030098588702400514"},{"key":"bibr4-vp.37-5-472","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1984.03350010055026"},{"key":"bibr5-vp.37-5-472","doi-asserted-by":"publisher","DOI":"10.1128\/mr.50.4.458-483.1986"},{"key":"bibr6-vp.37-5-472","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1515\/jom-1989-890211","volume":"89","author":"Goodstein RS","year":"1989","journal-title":"J Am Osteopath Assoc"},{"key":"bibr7-vp.37-5-472","first-page":"456","volume":"81","author":"Gross TL","year":"1986","journal-title":"Am J Gastroenterol"},{"key":"bibr8-vp.37-5-472","first-page":"562","volume":"107","author":"Guarda LA","year":"1983","journal-title":"Arch Pathol Lab Med"},{"key":"bibr9-vp.37-5-472","doi-asserted-by":"publisher","DOI":"10.3109\/00365548709032426"},{"key":"bibr10-vp.37-5-472","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0684.1993.tb00656.x"},{"key":"bibr11-vp.37-5-472","doi-asserted-by":"publisher","DOI":"10.1097\/00005176-198401000-00028"},{"key":"bibr12-vp.37-5-472","first-page":"35","volume":"188","author":"Lackner AA","year":"1994","journal-title":"Curr Top Microbiol Immunol"},{"key":"bibr13-vp.37-5-472","doi-asserted-by":"publisher","DOI":"10.1007\/BF01743372"},{"key":"bibr14-vp.37-5-472","first-page":"42","volume":"40","author":"Miller RA","year":"1990","journal-title":"Lab Anim Sci"},{"key":"bibr15-vp.37-5-472","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/161.2.312"},{"key":"bibr16-vp.37-5-472","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1982.31.226"},{"key":"bibr17-vp.37-5-472","doi-asserted-by":"publisher","DOI":"10.1089\/aid.1992.8.327"},{"key":"bibr18-vp.37-5-472","doi-asserted-by":"publisher","DOI":"10.1177\/030098588402100413"}],"container-title":["Veterinary Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1354\/vp.37-5-472","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1354\/vp.37-5-472","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1354\/vp.37-5-472","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T20:25:45Z","timestamp":1740860745000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1354\/vp.37-5-472"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,9]]},"references-count":18,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2000,9]]}},"alternative-id":["10.1354\/vp.37-5-472"],"URL":"https:\/\/doi.org\/10.1354\/vp.37-5-472","relation":{},"ISSN":["0300-9858","1544-2217"],"issn-type":[{"value":"0300-9858","type":"print"},{"value":"1544-2217","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,9]]}}}