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Neoplastic interstitial cells exhibited diffuse, granular cytoplasmic staining with Melan A, a marker of steroid-producing cells in humans and dogs. Multiple subcutaneous masses in the caudal abdomen were associated with enlarged nipples and consisted of hyperplastic mammary gland tissue with proliferation of ducts and alveoli, marked lobule formation, and pseudolactational hyperplasia. Many epithelial cells lining the hyperplastic ducts and alveoli exhibited intense nuclear expression of progesterone receptor antigen, whereas myoepithelial cells showed strong nuclear staining for p63 antigen. This is the first report of concurrent interstitial cell tumor and gynecomastia in a rabbit and also the first description of gynecomastia in this species. <\/jats:p>","DOI":"10.1354\/vp.44-4-513","type":"journal-article","created":{"date-parts":[[2007,7,2]],"date-time":"2007-07-02T15:56:15Z","timestamp":1183391775000},"page":"513-517","source":"Crossref","is-referenced-by-count":24,"title":["Testicular Interstitial Cell Tumor and Gynecomastia in a Rabbit"],"prefix":"10.1177","volume":"44","author":[{"given":"K. A.","family":"Maratea","sequence":"first","affiliation":[{"name":"Animal Disease Diagnostic Laboratory, School of Veterinary Medicine, Purdue University, West Lafayette, IN"},{"name":"Department of Comparative Pathobiology, School of Veterinary Medicine, Purdue University, West Lafayette, IN"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. 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