{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T09:29:02Z","timestamp":1792834142981,"version":"4.5.0"},"reference-count":11,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2007,11,1]],"date-time":"2007-11-01T00:00:00Z","timestamp":1193875200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vet Pathol"],"published-print":{"date-parts":[[2007,11]]},"abstract":"<jats:p> Craniofacial anomalies, eye malformations, and permanent flexures of the forelimbs are common malformations seen in ruminants grazing semiarid rangelands of Northeastern Brazil. To investigate the cause of these malformations, we fed 2 suspected plants, Mimosa tenuiflora or Prosopis juliflora, to groups of 4 pregnant goats each. Fresh green M. tenuiflora was collected daily and fed ad libitum to 4 goats in group 1 throughout pregnancy. This treatment group also received a supplemental feed concentrate equivalent to 1% body weight. Four goats in group 2 received a ration with 70% of P. juliflora pods and 30% hay throughout pregnancy. Four control goats were fed supplemental feed concentrate (1% body weight) and hay ad libitum throughout pregnancy. Goats treated with P. juliflora pods and the control goats delivered 9 normal kids. The four goats that were fed M. tenuiflora during pregnancy delivered 4 kids, 3 of which had abnormalities similar to those observed in field cases, including cleft lip, unilateral corneal opacity, ocular bilateral dermoids, buphthalmos with a cloudy brownish appearance of the anterior chamber due to an iridal cyst, and segmental stenosis of the colon. Malformations induced experimentally by M. tenuiflora were similar to those observed in field cases, suggesting that M. tenuiflora is a cause of the field cases observed in the Brazilian semiarid rangelands. <\/jats:p>","DOI":"10.1354\/vp.44-6-928","type":"journal-article","created":{"date-parts":[[2007,11,26]],"date-time":"2007-11-26T18:25:07Z","timestamp":1196101507000},"page":"928-931","source":"Crossref","is-referenced-by-count":54,"title":["<i>Mimosa tenuiflora<\/i> as a Cause of Malformations in Ruminants in the Northeastern Brazilian Semiarid Rangelands"],"prefix":"10.1177","volume":"44","author":[{"given":"L. A.","family":"Pimentel","sequence":"first","affiliation":[{"name":"Hospital Veterinario, CSTR, Universidade Federal de Campina Grande, Campus de Patos, Patos, Paraiba, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F. Riet","family":"Correa","sequence":"additional","affiliation":[{"name":"Hospital Veterinario, CSTR, Universidade Federal de Campina Grande, Campus de Patos, Patos, Paraiba, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Gardner","sequence":"additional","affiliation":[{"name":"USDA\/ARS Poisonous Plants Research Laboratory, Logan, Utah"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K. E.","family":"Panter","sequence":"additional","affiliation":[{"name":"USDA\/ARS Poisonous Plants Research Laboratory, Logan, Utah"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. F. M.","family":"Dantas","sequence":"additional","affiliation":[{"name":"Hospital Veterinario, CSTR, Universidade Federal de Campina Grande, Campus de Patos, Patos, Paraiba, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. M. T.","family":"Medeiros","sequence":"additional","affiliation":[{"name":"Hospital Veterinario, CSTR, Universidade Federal de Campina Grande, Campus de Patos, Patos, Paraiba, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. A.","family":"Mota","sequence":"additional","affiliation":[{"name":"Universidade Rural de Pernambuco. Rua Manuel de Medeiros S\/N, Dois Irmaos, Recife, Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. A. S.","family":"Araujo","sequence":"additional","affiliation":[{"name":"Hospital Veterinario, CSTR, Universidade Federal de Campina Grande, Campus de Patos, Patos, Paraiba, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2007,11,1]]},"reference":[{"key":"bibr1-vp.44-6-928","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-0813.1975.tb09437.x"},{"key":"bibr2-vp.44-6-928","unstructured":"2 Figueiredo APM, Ben\u00edcio TMA, Dantas FPM, Medeiros RMT, Riet-Correa F: The rat as an experimental model to study malformations caused by Mimosa tenuiflora. Proceedings of IX Congresso Brasileiro de Toxinologia, Fortaleza, Cear\u00e1, Brazil, 28 November-2 December 2007. Brazilian Society of Toxinology, Institute Butatantan, S\u00e3o Paolo, Brazil [abstract]"},{"key":"bibr3-vp.44-6-928","first-page":"1379","volume":"28","author":"James LF","year":"1967","journal-title":"Am J Vet Res"},{"key":"bibr4-vp.44-6-928","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-403250-7.50045-5"},{"key":"bibr5-vp.44-6-928","volume-title":"Arvores Brasileiras","volume":"2","author":"Lorenzi H","year":"1998","edition":"1"},{"key":"bibr6-vp.44-6-928","doi-asserted-by":"publisher","DOI":"10.1590\/S0100-736X2005000400002"},{"key":"bibr7-vp.44-6-928","doi-asserted-by":"publisher","DOI":"10.1590\/S0100-736X2005000300008"},{"key":"bibr8-vp.44-6-928","first-page":"345","volume-title":"Toxic Plants and Other Natural Toxicants","author":"Panter KE","year":"1998"},{"key":"bibr9-vp.44-6-928","first-page":"325","volume-title":"Plant-Associated Toxins","author":"Panter KE","year":"1994"},{"key":"bibr10-vp.44-6-928","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1590\/S0100-736X2004000200011","volume":"24","author":"Riet-Correa F","year":"2004","journal-title":"Pesq Vet Bras"},{"key":"bibr11-vp.44-6-928","volume-title":"Plantas Toxicas da Paraiba. 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