{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T15:53:37Z","timestamp":1790438017957,"version":"4.1.0"},"reference-count":116,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2005,9,1]],"date-time":"2005-09-01T00:00:00Z","timestamp":1125532800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2005,9,1]]},"DOI":"10.1359\/jbmr.050524","type":"journal-article","created":{"date-parts":[[2006,4,27]],"date-time":"2006-04-27T09:09:23Z","timestamp":1146128963000},"page":"1497-1506","source":"Crossref","is-referenced-by-count":79,"title":["Potential Role of Pancreatic and Enteric Hormones in Regulating Bone Turnover"],"prefix":"10.1093","volume":"20","author":[{"given":"Jackie A","family":"Clowes","sequence":"first","affiliation":[{"name":"Mayo Clinic College of Medicine, Endocrine Research Unit, St Mary's Hospital, Rochester, Minnesota, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sundeep","family":"Khosla","sequence":"additional","affiliation":[{"name":"Mayo Clinic College of Medicine, Endocrine Research Unit, St Mary's Hospital, Rochester, Minnesota, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Eastell","sequence":"additional","affiliation":[{"name":"Academic Unit of Bone Metabolism, Division of Clinical Sciences (North), University of Sheffield, Sheffield, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2009,12,4]]},"reference":[{"key":"2024013019251512100_bib1","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1097\/00042737-200308000-00004","article-title":"The pathophysiology of bone disease in gastrointestinal disease","volume":"15","author":"Bernstein","year":"2003","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"2024013019251512100_bib2","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1530\/eje.0.1400332","article-title":"Acute fasting diminishes the circadian rhythm of biochemical markers of bone resorption","volume":"140","author":"Schlemmer","year":"1999","journal-title":"Eur J Endocrinol"},{"key":"2024013019251512100_bib3","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1093\/clinchem\/46.3.431a","article-title":"Circadian variation in serum CrossLaps concentration is reduced in fasting individuals","volume":"46","author":"Christgau","year":"2000","journal-title":"Clin Chem"},{"key":"2024013019251512100_bib4","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/S8756-3282(01)00662-7","article-title":"Mechanism of circadian variation in bone resorption","volume":"30","author":"Bjarnason","year":"2002","journal-title":"Bone"},{"key":"2024013019251512100_bib5","doi-asserted-by":"crossref","first-page":"886","DOI":"10.1016\/S8756-3282(02)00728-7","article-title":"The Effect of Feeding on Bone Turnover Markers and its Impact on Biological Variability of Measurements","volume":"30","author":"Clowes","year":"2002","journal-title":"Bone"},{"key":"2024013019251512100_bib6","doi-asserted-by":"crossref","first-page":"4867","DOI":"10.1210\/jc.2002-021447","article-title":"Octreotide abolishes the acute decrease in bone turnover in response to oral glucose","volume":"88","author":"Clowes","year":"2003","journal-title":"J Clin Endocrinol Metab"},{"key":"2024013019251512100_bib7","doi-asserted-by":"crossref","first-page":"2180","DOI":"10.1359\/jbmr.2003.18.12.2180","article-title":"Role of gastrointestinal hormones in postprandial reduction of bone resorption","volume":"18","author":"Henriksen","year":"2003","journal-title":"J Bone Miner Res"},{"key":"2024013019251512100_bib8","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.1359\/jbmr.1999.14.8.1457","article-title":"Food fractionation is a powerful tool to increase bone mass in growing rats and to decrease bone loss in aged rats: Modulation of the effect by dietary phosphate","volume":"14","author":"Li","year":"1999","journal-title":"J Bone Miner Res"},{"key":"2024013019251512100_bib9","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1038\/nature03354","article-title":"Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1","volume":"434","author":"Rodgers","year":"2005","journal-title":"Nature"},{"key":"2024013019251512100_bib10","first-page":"730","article-title":"The effect of calcium supplementation on the circadian rhythm of bone resorption","volume":"79","author":"Blumsohn","year":"1994","journal-title":"J Clin Endocrinol Metab"},{"key":"2024013019251512100_bib11","doi-asserted-by":"crossref","first-page":"1510","DOI":"10.1093\/clinchem\/45.9.1510","article-title":"Total and free deoxypyridinoline after acute osteoclast activity inhibition","volume":"45","author":"Rubinacci","year":"1999","journal-title":"Clin Chem"},{"key":"2024013019251512100_bib12","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1093\/clinchem\/46.4.560e","article-title":"Response to acute osteoclast activity inhibition assessed by the determination of C-telopeptide of type I collagen in serum","volume":"46","author":"Villa","year":"2000","journal-title":"Clin Chem"},{"key":"2024013019251512100_bib13","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1007\/s002230001172","article-title":"Inhibition of bone resorption by divided-dose calcium supplementation in early postmenopausal women","volume":"67","author":"Scopacasa","year":"2000","journal-title":"Calcif Tissue Int"},{"key":"2024013019251512100_bib14","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1093\/ajcn\/60.6.965","article-title":"Oral calcium suppresses biochemical markers of bone resorption in normal men","volume":"60","author":"Horowitz","year":"1994","journal-title":"Am J Clin Nutr"},{"key":"2024013019251512100_bib15","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/0009-8981(75)90167-9","article-title":"An estimate of the turnover rate of bone-derived plasma alkaline phosphatase in Paget's disease","volume":"63","author":"Walton","year":"1975","journal-title":"Clin Chim Acta"},{"key":"2024013019251512100_bib16","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1053\/meta.2001.21694","article-title":"Effects of dietary restriction on appendicular bone in the SENCAR mouse","volume":"50","author":"Brochmann Murray","year":"2001","journal-title":"Metabolism"},{"key":"2024013019251512100_bib17","doi-asserted-by":"crossref","first-page":"1933","DOI":"10.1172\/JCI117875","article-title":"The diurnal rhythm of bone resorption in the rat. Effect of feeding habits and pharmacological inhibitors","volume":"95","author":"Muhlbauer","year":"1995","journal-title":"J Clin Invest"},{"key":"2024013019251512100_bib18","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/S8756-3282(01)00581-6","article-title":"Circadian and longitudinal variation of serum C-telopeptide, osteocalcin, and skeletal alkaline phosphatase in C3H\/HeJ mice","volume":"29","author":"Srivastava","year":"2001","journal-title":"Bone"},{"key":"2024013019251512100_bib19","first-page":"R235","article-title":"Diurnal rhythms in Ca transfer into bone, Ca release from bone, and bone resorbing activity in serum of rats","volume":"262","author":"Shinoda","year":"1992","journal-title":"Am J Physiol"},{"key":"2024013019251512100_bib20","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1111\/j.1365-2265.1994.tb02493.x","article-title":"Alteration of the circadian rhythm of intact parathyroid hormone following a 96-hour fast","volume":"40","author":"Fraser","year":"1994","journal-title":"Clin Endocrinol (Oxf)"},{"key":"2024013019251512100_bib21","first-page":"3304","article-title":"Role of parathyroid hormone in mediating nocturnal and age-related increases in bone resorption","volume":"80","author":"Ledger","year":"1995","journal-title":"J Clin Endocrinol Metab"},{"key":"2024013019251512100_bib22","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1111\/j.1365-2265.1980.tb01377.x","article-title":"Circulating somatostatin after food and glucose in man","volume":"12","author":"Wass","year":"1980","journal-title":"Clin Endocrinol (Oxf)"},{"key":"2024013019251512100_bib23","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1172\/JCI110966","article-title":"Neuroendocrine responses to glucose ingestion in man. Specificity, temporal relationships, and quantitative aspects","volume":"72","author":"Tse","year":"1983","journal-title":"J Clin Invest"},{"key":"2024013019251512100_bib24","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1042\/bst0240585","article-title":"The metabolic role of GIP: Physiology and pathology","volume":"24","author":"Morgan","year":"1996","journal-title":"Biochem Soc Trans"},{"key":"2024013019251512100_bib25","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1056\/NEJM198101293040505","article-title":"Calcitonin: Physiology and pathophysiology","volume":"304","author":"Austin","year":"1981","journal-title":"N Engl J Med"},{"key":"2024013019251512100_bib26","doi-asserted-by":"crossref","first-page":"1228","DOI":"10.1210\/endo.141.3.7366","article-title":"Osteoblast-derived cells express functional glucose-dependent insulinotropic peptide receptors","volume":"141","author":"Bollag","year":"2000","journal-title":"Endocrinology"},{"key":"2024013019251512100_bib27","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/S8756-3282(01)00494-X","article-title":"Effects of calcitonin, amylin, and calcitonin gene-related peptide on osteoclast development","volume":"29","author":"Cornish","year":"2001","journal-title":"Bone"},{"key":"2024013019251512100_bib28","doi-asserted-by":"crossref","first-page":"4161","DOI":"10.1210\/en.2002-220843","article-title":"Leptin-central or peripheral to the regulation of bone metabolism?","volume":"143","author":"Khosla","year":"2002","journal-title":"Endocrinology"},{"key":"2024013019251512100_bib29","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/8756-3282(95)00447-5","article-title":"Effect of nasal salmon calcitonin on bone remodeling and bone mass in postmenopausal osteoporosis","volume":"18","author":"Thamsborg","year":"1996","journal-title":"Bone"},{"key":"2024013019251512100_bib30","first-page":"417","article-title":"Acute oral calcium-sodium citrate load in healthy males. Effects on acid-base and mineral metabolism, oxalate and other risk factors of stone formation in urine","volume":"19","author":"Schwille","year":"1997","journal-title":"Methods Find Exp Clin Pharmacol"},{"key":"2024013019251512100_bib31","first-page":"E694","article-title":"Systemic administration of amylin increases bone mass, linear growth, and adiposity in adult male mice","volume":"275","author":"Cornish","year":"1998","journal-title":"Am J Physiol"},{"key":"2024013019251512100_bib32","doi-asserted-by":"crossref","first-page":"E730","DOI":"10.1152\/ajpendo.2000.279.4.E730","article-title":"Systemic administration of a novel octapeptide, amylin-(1\u20138), increases bone volume in male mice","volume":"279","author":"Cornish","year":"2000","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"2024013019251512100_bib33","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/S0303-7207(01)00405-1","article-title":"Glucose-dependent insulinotropic peptide is an integrative hormone with osteotropic effects","volume":"177","author":"Bollag","year":"2001","journal-title":"Mol Cell Endocrinol"},{"key":"2024013019251512100_bib34","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1080\/003655202317316006","article-title":"Short-term administration of glucagon-like peptide-2. Effects on bone mineral density and markers of bone turnover in short-bowel patients with no colon","volume":"37","author":"Haderslev","year":"2002","journal-title":"Scand J Gastroenterol"},{"key":"2024013019251512100_bib35","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1172\/JCI110967","article-title":"Mechanisms of postprandial glucose counterregulation in man. Physiologic roles of glucagon and epinephrine vis-a-vis insulin in the prevention of hypoglycemia late after glucose ingestion","volume":"72","author":"Tse","year":"1983","journal-title":"J Clin Invest"},{"key":"2024013019251512100_bib36","first-page":"751","article-title":"Effects of the circadian variation in serum cortisol on markers of bone turnover and calcium homeostasis in normal postmenopausal women","volume":"83","author":"Heshmati","year":"1998","journal-title":"J Clin Endocrinol Metab"},{"key":"2024013019251512100_bib37","first-page":"3185","article-title":"Circadian rhythm of in vitro bone-resorbing activity in human serum","volume":"80","author":"Lakatos","year":"1995","journal-title":"J Clin Endocrinol Metab"},{"key":"2024013019251512100_bib38","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1146\/annurev.physiol.63.1.119","article-title":"The gastrins: Their production and biological activities","volume":"63","author":"Dockray","year":"2001","journal-title":"Annu Rev Physiol"},{"key":"2024013019251512100_bib39","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/S8756-3282(98)00095-7","article-title":"Insulin receptor expression in primary and cultured osteoclast-like cells","volume":"23","author":"Thomas","year":"1998","journal-title":"Bone"},{"key":"2024013019251512100_bib40","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1006\/bbrc.1997.6795","article-title":"Regulation of osteoclastic bone resorption by glucose","volume":"235","author":"Williams","year":"1997","journal-title":"Biochem Biophys Res Commun"},{"key":"2024013019251512100_bib41","doi-asserted-by":"crossref","first-page":"3323","DOI":"10.1210\/jcem.87.7.8660","article-title":"Acute changes of bone turnover and parathyroid hormone induced by insulin and glucose: Euglycemic and hypoglycemic hyperinsulinemic clamp studies","volume":"87","author":"Clowes","year":"2002","journal-title":"J Clin Endocrinol Metab"},{"key":"2024013019251512100_bib42","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1172\/JCI107996","article-title":"The effect of insulin on renal handling of sodium, potassium, calcium, and phosphate in man","volume":"55","author":"DeFronzo","year":"1975","journal-title":"J Clin Invest"},{"key":"2024013019251512100_bib43","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1172\/JCI108463","article-title":"The effects of glucose and insulin on renal electrolyte transport","volume":"58","author":"DeFronzo","year":"1976","journal-title":"J Clin Invest"},{"key":"2024013019251512100_bib44","doi-asserted-by":"crossref","first-page":"2566","DOI":"10.1093\/ndt\/13.10.2566","article-title":"The influence of hyperinsulinaemia on calcium-phosphate metabolism in renal failure","volume":"13","author":"Nowicki","year":"1998","journal-title":"Nephrol Dial Transplant"},{"key":"2024013019251512100_bib45","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1291\/hypres.23.433","article-title":"Insulin sensitivity and calcium homeostasis in young, lean, normotensive male subjects","volume":"23","author":"Ohno","year":"2000","journal-title":"Hypertens Res"},{"key":"2024013019251512100_bib46","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1007\/BF02556090","article-title":"Intestinal calcium absorption during hyperinsulinemic euglycemic glucose clamp in healthy humans","volume":"46","author":"Rumenapf","year":"1990","journal-title":"Calcif Tissue Int"},{"key":"2024013019251512100_bib47","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1016\/0026-0495(79)90096-9","article-title":"Role of endogenous somatostatin in the secretion of parathyroid hormone and calcitonin","volume":"28","author":"Williams","year":"1979","journal-title":"Metabolism"},{"key":"2024013019251512100_bib48","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1111\/j.1365-2036.1987.tb00632.x","article-title":"The effect of a long-acting somatostatin analogue (SMS 201-995) on intermediary metabolism and gut hormones after a test meal in normal subjects","volume":"1","author":"Fuessl","year":"1987","journal-title":"Aliment Pharmacol Ther"},{"key":"2024013019251512100_bib49","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1210\/edrv-9-4-417","article-title":"The role of somatostatin in the regulation of anterior pituitary hormone secretion and the use of its analogs in the treatment of human pituitary tumors","volume":"9","author":"Lamberts","year":"1988","journal-title":"Endocr Rev"},{"key":"2024013019251512100_bib50","first-page":"E827","article-title":"Dissociation of the effects of amylin on osteoblast proliferation and bone resorption","volume":"274","author":"Cornish","year":"1998","journal-title":"Am J Physiol"},{"key":"2024013019251512100_bib51","doi-asserted-by":"crossref","first-page":"1302","DOI":"10.1359\/jbmr.1999.14.8.1302","article-title":"Comparison of the effects of calcitonin gene-related peptide and amylin on osteoblasts","volume":"14","author":"Cornish","year":"1999","journal-title":"J Bone Miner Res"},{"key":"2024013019251512100_bib52","first-page":"S1","article-title":"GLP-2 reduces bone resorption in vitro via the osteoclast GLP-2 receptor","volume":"19","author":"Karsdal","year":"2004","journal-title":"J Bone Miner Res"},{"key":"2024013019251512100_bib53","first-page":"S1","article-title":"Glucose-dependent insulinotropic peptide regulates bone turnover in vivo","volume":"19","author":"Xie","year":"2004","journal-title":"J Bone Miner Res"},{"key":"2024013019251512100_bib54","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1083\/jcb.200312135","article-title":"Amylin inhibits bone resorption while the calcitonin receptor controls bone formation in vivo","volume":"164","author":"Dacquin","year":"2004","journal-title":"J Cell Biol"},{"key":"2024013019251512100_bib55","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1677\/joe.0.1750405","article-title":"Leptin directly regulates bone cell function in vitro and reduces bone fragility in vivo","volume":"175","author":"Cornish","year":"2002","journal-title":"J Endocrinol"},{"key":"2024013019251512100_bib56","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1007\/s001250051210","article-title":"Nutritional regulation of leptin in humans","volume":"42","author":"Coleman","year":"1999","journal-title":"Diabetologia"},{"key":"2024013019251512100_bib57","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1359\/jbmr.2002.17.2.200","article-title":"Leptin inhibits osteoclast generation","volume":"17","author":"Holloway","year":"2002","journal-title":"J Bone Miner Res"},{"key":"2024013019251512100_bib58","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1002\/jcb.20388","article-title":"Normal human osteoclasts formed from peripheral blood monocytes express PTH type 1 receptors and are stimulated by PTH in the absence of osteoblasts","volume":"95","author":"Dempster","year":"2005","journal-title":"J Cell Biochem"},{"key":"2024013019251512100_bib59","doi-asserted-by":"crossref","first-page":"1522","DOI":"10.1038\/ki.1990.144","article-title":"Effects of high concentrations of glucose on PTH secretion in parathyroid cells","volume":"37","author":"Sugimoto","year":"1990","journal-title":"Kidney Int"},{"key":"2024013019251512100_bib60","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1210\/endo-128-1-488","article-title":"Effects of insulin on the synthesis, intracellular degradation, and secretion of parathormone","volume":"128","author":"Hinton","year":"1991","journal-title":"Endocrinology"},{"key":"2024013019251512100_bib61","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1210\/jcem-56-3-549","article-title":"Effect of meal on serum parathyroid hormone and calcitonin: Possible role of secretin","volume":"56","author":"Sethi","year":"1983","journal-title":"J Clin Endocrinol Metab"},{"key":"2024013019251512100_bib62","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1055\/s-2007-978731","article-title":"Calcium homeostasis during oral glucose load in healthy women","volume":"31","author":"D'Erasmo","year":"1999","journal-title":"Horm Metab Res"},{"key":"2024013019251512100_bib63","first-page":"1270","article-title":"Suppression of plasma intact parathyroid hormone levels during insulin- induced hypoglycemia in humans","volume":"74","author":"Shearing","year":"1992","journal-title":"J Clin Endocrinol Metab"},{"key":"2024013019251512100_bib64","first-page":"156","article-title":"Changes in plasma phosphate levels influence insulin sensitivity under euglycemic conditions","volume":"81","author":"Nowicki","year":"1996","journal-title":"J Clin Endocrinol Metab"},{"key":"2024013019251512100_bib65","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1007\/BF02010358","article-title":"A new tracer method for the calculation of rates of bone formation and breakdown in osteoporosis and other generalised skeletal disorders","volume":"22","author":"Reeve","year":"1976","journal-title":"Calcif Tissue Res"},{"key":"2024013019251512100_bib66","first-page":"864","article-title":"Widespread expression of the parathyroid hormone-related peptide and PTH\/PTHrP receptor genes in intestinal epithelial cells","volume":"73","author":"Li","year":"1995","journal-title":"Lab Invest"},{"key":"2024013019251512100_bib67","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0303-7207(01)00482-8","article-title":"PTHrP increases pancreatic beta-cell-specific functions in well-differentiated cells","volume":"182","author":"Sawada","year":"2001","journal-title":"Mol Cell Endocrinol"},{"key":"2024013019251512100_bib68","doi-asserted-by":"crossref","first-page":"1769","DOI":"10.1172\/JCI200217425","article-title":"Calcitonin and bone formation: A knockout full of surprises","volume":"110","author":"Zaidi","year":"2002","journal-title":"J Clin Invest"},{"key":"2024013019251512100_bib69","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1210\/endo-110-3-961","article-title":"Feeding regimen, dietary calcium, and the diurnal rhythms of serum calcium and calcitonin in the rat","volume":"110","author":"Hirsch","year":"1982","journal-title":"Endocrinology"},{"key":"2024013019251512100_bib70","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1007\/BF01072883","article-title":"Comparison of the effects of pentagastrin and meal-stimulated gastrin on plasma calcitonin in normal man","volume":"23","author":"Owyang","year":"1978","journal-title":"Am J Dig Dis"},{"key":"2024013019251512100_bib71","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/0169-6009(90)90059-O","article-title":"Partial gastrectomy and mineral metabolism: Effects on gastrin- calcitonin release","volume":"11","author":"Filipponi","year":"1990","journal-title":"Bone Miner"},{"key":"2024013019251512100_bib72","doi-asserted-by":"crossref","first-page":"1849","DOI":"10.1172\/JCI200214218","article-title":"Increased bone mass is an unexpected phenotype associated with deletion of the calcitonin gene","volume":"110","author":"Hoff","year":"2002","journal-title":"J Clin Invest"},{"key":"2024013019251512100_bib73","first-page":"55","article-title":"Growth hormone and bone","volume":"19","author":"Ohlsson","year":"1998","journal-title":"Endocr Rev"},{"key":"2024013019251512100_bib74","first-page":"801","article-title":"Insulin-like growth factor-binding proteins in serum and other biological fluids: Regulation and functions","volume":"18","author":"Rajaram","year":"1997","journal-title":"Endocr Rev"},{"key":"2024013019251512100_bib75","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1172\/JCI113450","article-title":"Fasting enhances growth hormone secretion and amplifies the complex rhythms of growth hormone secretion in man","volume":"81","author":"Ho","year":"1988","journal-title":"J Clin Invest"},{"key":"2024013019251512100_bib76","first-page":"80","article-title":"Nutritional regulation of the insulin-like growth factors","volume":"15","author":"Thissen","year":"1994","journal-title":"Endocr Rev"},{"key":"2024013019251512100_bib77","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1210\/jcem-73-2-368","article-title":"The nocturnal increase in growth hormone is not the cause of the nocturnal increase in serum osteocalcin","volume":"73","author":"Ebeling","year":"1991","journal-title":"J Clin Endocrinol Metab"},{"key":"2024013019251512100_bib78","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1530\/eje.0.1460203","article-title":"Ghrelin drives GH secretion during fasting in man","volume":"146","author":"Muller","year":"2002","journal-title":"Eur J Endocrinol"},{"key":"2024013019251512100_bib79","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1677\/joe.1.05837","article-title":"Ghrelin regulates proliferation and differentiation of osteoblastic cells","volume":"184","author":"Maccarinelli","year":"2005","journal-title":"J Endocrinol"},{"key":"2024013019251512100_bib80","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1172\/JCI200421134","article-title":"Ghrelin inhibits leptin- and activation-induced proinflammatory cytokine expression by human monocytes and T cells","volume":"114","author":"Dixit","year":"2004","journal-title":"J Clin Invest"},{"key":"2024013019251512100_bib81","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1054\/ghir.1999.0105","article-title":"Hexarelin, a growth hormone - releasing peptide, counteracts bone loss in gonadectomized male rats","volume":"9","author":"Sibilia","year":"1999","journal-title":"Growth Horm IGF Res"},{"key":"2024013019251512100_bib82","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1530\/eje.0.1460855","article-title":"Bone effects of hexarelin, a GH-releasing peptide, in female rats: Influence of estrogen milieu","volume":"146","author":"Sibilia","year":"2002","journal-title":"Eur J Endocrinol"},{"key":"2024013019251512100_bib83","doi-asserted-by":"crossref","first-page":"7973","DOI":"10.1128\/MCB.23.22.7973-7981.2003","article-title":"Deletion of ghrelin impairs neither growth nor appetite","volume":"23","author":"Sun","year":"2003","journal-title":"Mol Cell Biol"},{"key":"2024013019251512100_bib84","doi-asserted-by":"crossref","first-page":"1662","DOI":"10.1210\/jc.2003-031207","article-title":"Ghrelin secretion in childhood is refractory to the inhibitory effect of feeding","volume":"89","author":"Bellone","year":"2004","journal-title":"J Clin Endocrinol Metab"},{"key":"2024013019251512100_bib85","first-page":"S1","article-title":"The postprandial bone resorption process is regulated by gastrointestinal signal","volume":"19","author":"Henriksen","year":"2004","journal-title":"J Bone Miner Res"},{"key":"2024013019251512100_bib86","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1159\/000176284","article-title":"Simultaneous correction of Ca deficiency and acidosis in fasting obese patients as a prevention of bone demineralisation","volume":"23","author":"Kocian","year":"1979","journal-title":"Nutr Metab"},{"key":"2024013019251512100_bib87","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1359\/JBMR.040204","article-title":"Dietary protein and bone health","volume":"19","author":"Rizzoli","year":"2004","journal-title":"J Bone Miner Res"},{"key":"2024013019251512100_bib88","doi-asserted-by":"crossref","first-page":"1230","DOI":"10.1359\/jbmr.2002.17.7.1230","article-title":"Onion and a mixture of vegetables, salads, and herbs affect bone resorption in the rat by a mechanism independent of their base excess","volume":"17","author":"Muhlbauer","year":"2002","journal-title":"J Bone Miner Res"},{"key":"2024013019251512100_bib89","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1080\/003655202317316079","article-title":"Post-gastrectomy osteopenia in the rat: Bone structure is preserved by retaining 10%\u201330% of the oxyntic gland area","volume":"37","author":"Lehto-Axtelius","year":"2002","journal-title":"Scand J Gastroenterol"},{"key":"2024013019251512100_bib90","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1016\/S0015-0282(01)01686-7","article-title":"Endocrine and chronobiological effects of fasting in women","volume":"75","author":"Berga","year":"2001","journal-title":"Fertil Steril"},{"key":"2024013019251512100_bib91","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1210\/jcem-73-1-35","article-title":"Slowing of pulsatile luteinizing hormone secretion in men after forty-eight hours of fasting","volume":"73","author":"Cameron","year":"1991","journal-title":"J Clin Endocrinol Metab"},{"key":"2024013019251512100_bib92","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1042\/cs0970429","article-title":"Splanchnic and extrasplanchnic extraction of insulin following oral and intravenous glucose loads","volume":"97","author":"Brundin","year":"1999","journal-title":"Clin Sci (Lond)"},{"key":"2024013019251512100_bib93","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1046\/j.1365-2281.2001.00316.x","article-title":"Renal extraction of insulin and C-peptide in man before and after a glucose meal","volume":"21","author":"Samnegard","year":"2001","journal-title":"Clin Physiol"},{"key":"2024013019251512100_bib94","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1042\/bj2280415","article-title":"Studies in vivo and in vitro on the uptake and degradation of soluble collagen alpha 1(I) chains in rat liver endothelial and Kupffer cells","volume":"228","author":"Smedsrod","year":"1985","journal-title":"Biochem J"},{"key":"2024013019251512100_bib95","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1007\/BF02556332","article-title":"The metabolic clearance rate of osteocalcin in sheep","volume":"42","author":"Melick","year":"1988","journal-title":"Calcif Tissue Int"},{"key":"2024013019251512100_bib96","doi-asserted-by":"crossref","first-page":"1976","DOI":"10.1002\/jbmr.5650111220","article-title":"The renal clearance of free and conjugated pyridinium cross-links of collagen","volume":"11","author":"Colwell","year":"1996","journal-title":"J Bone Miner Res"},{"key":"2024013019251512100_bib97","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1111\/j.1365-2362.1993.tb02034.x","article-title":"Factors affecting the assay of urinary 3-hydroxy pyridinium crosslinks of collagen as markers of bone resorption","volume":"23","author":"Colwell","year":"1993","journal-title":"Eur J Clin Invest"},{"key":"2024013019251512100_bib98","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1038\/43824","article-title":"Effect of vegetables on bone metabolism","volume":"401","author":"Muhlbauer","year":"1999","journal-title":"Nature"},{"key":"2024013019251512100_bib99","doi-asserted-by":"crossref","first-page":"3592","DOI":"10.1093\/jn\/133.11.3592","article-title":"Various selected vegetables, fruits, mushrooms and red wine residue inhibit bone resorption in rats","volume":"133","author":"Muhlbauer","year":"2003","journal-title":"J Nutr"},{"key":"2024013019251512100_bib100","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1016\/S8756-3282(03)00027-9","article-title":"Common herbs, essential oils, and monoterpenes potently modulate bone metabolism","volume":"32","author":"Muhlbauer","year":"2003","journal-title":"Bone"},{"key":"2024013019251512100_bib101","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1359\/jbmr.040115","article-title":"Oxysterols regulate differentiation of mesenchymal stem cells: Pro-bone and anti-fat","volume":"19","author":"Kha","year":"2004","journal-title":"J Bone Miner Res"},{"key":"2024013019251512100_bib102","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1002\/jcb.20071","article-title":"Flavonoid quercetin decreases osteoclastic differentiation induced by RANKL via a mechanism involving NF kappa B and AP-1","volume":"92","author":"Wattel","year":"2004","journal-title":"J Cell Biochem"},{"key":"2024013019251512100_bib103","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1210\/er.2001-7002","article-title":"Meta-analyses of therapies for postmenopausal osteoporosis. VII. Meta-analysis of calcium supplementation for the prevention of postmenopausal osteoporosis","volume":"23","author":"Shea","year":"2002","journal-title":"Endocr Rev"},{"key":"2024013019251512100_bib104","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1093\/ajcn\/71.1.142","article-title":"Dietary influences on bone mass and bone metabolism: Further evidence of a positive link between fruit and vegetable consumption and bone health?","volume":"71","author":"New","year":"2000","journal-title":"Am J Clin Nutr"},{"key":"2024013019251512100_bib105","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1093\/ajcn\/76.1.245","article-title":"Bone mineral density and dietary patterns in older adults: The Framingham Osteoporosis Study","volume":"76","author":"Tucker","year":"2002","journal-title":"Am J Clin Nutr"},{"key":"2024013019251512100_bib106","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1093\/ajcn\/79.2.311","article-title":"Fruit and vegetable intakes are an independent predictor of bone size in early pubertal children","volume":"79","author":"Tylavsky","year":"2004","journal-title":"Am J Clin Nutr"},{"key":"2024013019251512100_bib107","doi-asserted-by":"crossref","first-page":"1112","DOI":"10.1359\/JBMR.040319","article-title":"Imbalance of osteoclastogenesis-regulating factors in patients with celiac disease","volume":"19","author":"Taranta","year":"2004","journal-title":"J Bone Miner Res"},{"key":"2024013019251512100_bib108","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1053\/gast.2001.22555","article-title":"Glucagon-like peptide 2 improves nutrient absorption and nutritional status in short-bowel patients with no colon","volume":"120","author":"Jeppesen","year":"2001","journal-title":"Gastroenterology"},{"key":"2024013019251512100_bib109","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1016\/S0006-291X(02)00697-6","article-title":"Leptin prevents the fall in plasma osteocalcin during starvation in male mice","volume":"295","author":"Goldstone","year":"2002","journal-title":"Biochem Biophys Res Commun"},{"key":"2024013019251512100_bib110","doi-asserted-by":"crossref","first-page":"1622","DOI":"10.1359\/jbmr.1999.14.9.1622","article-title":"Low body mass index is an important risk factor for low bone mass and increased bone loss in early postmenopausal women. Early Postmenopausal Intervention Cohort (EPIC) study group","volume":"14","author":"Ravn","year":"1999","journal-title":"J Bone Miner Res"},{"key":"2024013019251512100_bib111","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1001\/archinte.1997.00440290041004","article-title":"Weight change and fractures in older women. Study of Osteoporotic Fractures Research Group","volume":"157","author":"Ensrud","year":"1997","journal-title":"Arch Intern Med"},{"key":"2024013019251512100_bib112","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1007\/BF02555743","article-title":"The role of serum concentrations of sex steroids and bone turnover in the development and occurrence of postmenopausal osteoporosis","volume":"38","author":"Riis","year":"1986","journal-title":"Calcif Tissue Int"},{"key":"2024013019251512100_bib113","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1093\/oxfordjournals.aje.a009362","article-title":"Bone mass, lean mass, and fat mass: Same genes or same environments?","volume":"147","author":"Nguyen","year":"1998","journal-title":"Am J Epidemiol"},{"key":"2024013019251512100_bib114","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1046\/j.1365-2265.2001.01361.x","article-title":"Plasma leptin concentrations are associated with bone mineral density and the presence of vertebral fractures in postmenopausal women","volume":"55","author":"Yamauchi","year":"2001","journal-title":"Clin Endocrinol (Oxf)"},{"key":"2024013019251512100_bib115","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1016\/S0140-6736(81)92704-5","article-title":"Metabolic bone disease in total parenteral nutrition","volume":"1","author":"Klein","year":"1981","journal-title":"Lancet"},{"key":"2024013019251512100_bib116","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1007\/s11894-004-0087-1","article-title":"Metabolic bone disease and parenteral nutrition","volume":"6","author":"Hamilton","year":"2004","journal-title":"Curr Gastroenterol Rep"}],"container-title":["Journal of Bone and Mineral Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1359%2FJBMR.050524","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/academic.oup.com\/jbmr\/article-pdf\/20\/9\/1497\/56475055\/5650200901.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jbmr\/article-pdf\/20\/9\/1497\/56475055\/5650200901.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,13]],"date-time":"2024-03-13T15:09:43Z","timestamp":1710342583000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jbmr\/article\/20\/9\/1497-1506\/7592821"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,9,1]]},"references-count":116,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2009,12,4]]},"published-print":{"date-parts":[[2005,9,1]]}},"URL":"https:\/\/doi.org\/10.1359\/jbmr.050524","relation":{},"ISSN":["0884-0431","1523-4681"],"issn-type":[{"value":"0884-0431","type":"print"},{"value":"1523-4681","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2005,9,1]]},"published":{"date-parts":[[2005,9,1]]}}}