{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T11:57:51Z","timestamp":1790423871525,"version":"4.1.0"},"reference-count":37,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2008,3,1]],"date-time":"2008-03-01T00:00:00Z","timestamp":1204329600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2008,3,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>In this large population-based prospective study among middle-aged and older men and women, we found that height loss of &amp;gt;2 cm over a period of 4 yr is a significant predictor of future fractures. Serial measurement of height is, therefore, recommended among the elderly people.<\/jats:p>\n               <jats:p>Introduction: Height change can be easily measured and may contribute to fracture risk prediction. We assessed measured height loss and fracture incidence in a prospective population study.<\/jats:p>\n               <jats:p>Materials and Methods: Height was measured in participants in the Norfolk cohort of the European Prospective Investigation into Cancer (EPIC-Norfolk) between 1993 and 1997 and repeated between 1997 and 2000. Incident fractures to 2006 were ascertained by hospital record linkage.<\/jats:p>\n               <jats:p>Results: In 14,921 men and women 42\u201382 yr of age, during a mean follow-up period of 7.1 yr, there were 390 fractures, including 122 hip fractures. Prior annual height loss in those who had an incident fracture (1.8 \u00b1 0.3 [SD] mm) was significantly greater than other participants (0.9 \u00b1 0.2 mm; p &amp;lt; 0.001). Participants with annual height loss &amp;gt;0.5 cm had an age- and sex-adjusted hazard ratio of any fracture of 1.76 (95% CI, 1.16\u20132.67) and of hip fracture of 2.08 (95% CI, 1.07\u20134.05) compared with those with no height loss. Each 1 cm\/yr height loss was associated with a hazard ratio of 1.86 (95% CI, 1.28\u20132.72) for all fractures and 2.24 (95% CI, 1.23\u20134.09) for hip fracture after adjustment for age, sex, past history of fracture, smoking, body mass index, alcohol intake, and heel ultrasound measures. Annual height loss of 1 cm was comparable to having a past history of fracture and equivalent to being \u223c14 yr older in chronological age in terms of the magnitude of relationship with fracture risk.<\/jats:p>\n               <jats:p>Conclusions: Middle-aged and older men and women with annual height loss &amp;gt;0.5 cm are at increased risk of hip and any fracture. Serial height measurements can contribute to fracture risk prediction.<\/jats:p>","DOI":"10.1359\/jbmr.071106","type":"journal-article","created":{"date-parts":[[2007,11,12]],"date-time":"2007-11-12T19:57:53Z","timestamp":1194897473000},"page":"425-432","source":"Crossref","is-referenced-by-count":48,"title":["Measured Height Loss Predicts Fractures in Middle-Aged and Older Men and Women: The EPIC-Norfolk Prospective Population Study"],"prefix":"10.1093","volume":"23","author":[{"given":"Alireza","family":"Moayyeri","sequence":"first","affiliation":[{"name":"Department of Public Health and Primary Care, Institute of Public Health, School of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert N","family":"Luben","sequence":"additional","affiliation":[{"name":"Department of Public Health and Primary Care, Institute of Public Health, School of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheila A","family":"Bingham","sequence":"additional","affiliation":[{"name":"MRC Dunn Human Nutrition Unit, Cambridge, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ailsa A","family":"Welch","sequence":"additional","affiliation":[{"name":"Department of Public Health and Primary Care, Institute of Public Health, School of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas J","family":"Wareham","sequence":"additional","affiliation":[{"name":"Department of Public Health and Primary Care, Institute of Public Health, School of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kay-Tee","family":"Khaw","sequence":"additional","affiliation":[{"name":"Department of Public Health and Primary Care, Institute of Public Health, School of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2009,12,4]]},"reference":[{"key":"2024020319453915900_bib1","doi-asserted-by":"crossref","first-page":"1350","DOI":"10.1136\/bmj.319.7221.1350","article-title":"How many, how old, how soon?","volume":"319","author":"Khaw","year":"1999","journal-title":"BMJ"},{"key":"2024020319453915900_bib2","first-page":"646","article-title":"Burden of major musculoskeletal conditions","volume":"81","author":"Woolf","year":"2003","journal-title":"Bull World Health Organ"},{"key":"2024020319453915900_bib3","doi-asserted-by":"crossref","first-page":"1982","DOI":"10.1359\/jbmr.040901","article-title":"When should the doctor order a spine X-ray? 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