{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T07:13:46Z","timestamp":1761894826925},"reference-count":38,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2009,5,1]],"date-time":"2009-05-01T00:00:00Z","timestamp":1241136000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2009,5,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>The aim of this prospective study was to develop a risk score, based on putative risk factors in current guidelines, which can be used to identify women at high risk of fractures in general practice. The study sample included 4157 women \u226560 yr of age (mean \u00b1 SD: 74.1 \u00b1 9.1 yr), with a median follow-up of 8.9 yr of the Rotterdam Study (ERGO), and 762 women \u226565 yr of age (mean \u00b1 SD: 76.0 \u00b1 6.7.yr), with a median follow-up of 6.0 yr of the Longitudinal Aging Study Amsterdam (LASA). Potential risk factors were those proposed in risk scores of three recent guidelines on osteoporosis: age, family history of fractures, prior fracture, low body weight\/body mass index (BMI), serious immobility, rheumatoid arthritis, current smoking, alcohol consumption &amp;gt;2 units daily, prevalent vertebral fracture, and systemic corticosteroid use. Five-year absolute risk of hip fracture was 3.9% in the Rotterdam Study and 3.1% in LASA, and 10-yr absolute risk of hip fracture was 8.4% in the Rotterdam Study. Using Cox regression analysis, age (70\u201379 and 80+ versus &amp;lt;60\u201369) and four other risk factors were included in the risk profiles of hip fractures and fragility fractures: any prior fracture after age 50, body weight &amp;lt;64 kg, use of a walking aid as a proxy measure of serious immobility, and current smoking. Estimated 10-yr absolute risk of hip fracture ranged from 1.4% in women, age 60\u201369 years, without any of these predictors to 29% in women, \u226580 yr of age, having two or more positive risk factors. A simple risk score can satisfactorily identify older women at high risk of osteoporotic fractures in general practice. Future studies are needed to validate this score.<\/jats:p>","DOI":"10.1359\/jbmr.081244","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T20:01:01Z","timestamp":1230580861000},"page":"768-774","source":"Crossref","is-referenced-by-count":38,"title":["A Simple Risk Score for the Assessment of Absolute Fracture Risk in General Practice Based on Two Longitudinal Studies"],"prefix":"10.1093","volume":"24","author":[{"given":"Saskia MF","family":"Pluijm","sequence":"first","affiliation":[{"name":"Department of Public Health, Erasmus MC, Rotterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bart","family":"Koes","sequence":"additional","affiliation":[{"name":"Department of General Practice, Erasmus MC, Rotterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chris","family":"de Laet","sequence":"additional","affiliation":[{"name":"Belgian Health Care Knowledge Centre, Brussels, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natasja M","family":"Van Schoor","sequence":"additional","affiliation":[{"name":"Institute for Research in Extramural Medicine, VU University Medical Center (Vumc), Amsterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natalia O","family":"Kuchuk","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, VU University Medical Center (Vumc), Amsterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernando","family":"Rivadeneira","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics, Erasmus MC, Rotterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johan P","family":"Mackenbach","sequence":"additional","affiliation":[{"name":"Department of Public Health, Erasmus MC, Rotterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul","family":"Lips","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, VU University Medical Center (Vumc), Amsterdam, The Netherlands"},{"name":"Institute for Research in Extramural Medicine, VU University Medical Center (Vumc), Amsterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huibert A","family":"Pols","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ewout W","family":"Steyerberg","sequence":"additional","affiliation":[{"name":"Department of Public Health, Erasmus MC, Rotterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2009,12,4]]},"reference":[{"key":"2024020320014363600_bib1","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1007\/BF01623184","article-title":"Hip fractures in the elderly: A world-wide projection","volume":"2","author":"Cooper","year":"1992","journal-title":"Osteoporos Int"},{"key":"2024020320014363600_bib2","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1002\/jbmr.5650070902","article-title":"Perspective. 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