{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T22:46:58Z","timestamp":1761518818770},"reference-count":9,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2003,1,1]],"date-time":"2003-01-01T00:00:00Z","timestamp":1041379200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2003,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>A 69-year-old woman was diagnosed with a malignant tumor of the right proximal femur. She had primary hyperparathyroidism and chronic elevation of parathyroid hormone levels (PTH &amp;gt; 1000 pg\/ml). She underwent resection of the bone lesion; histological analysis showed a high-grade fibroblastic osteosarcoma. In addition, she underwent curative resection of a large left superior parathyroid adenoma. To our knowledge, this is the third reported clinical case of osteosarcoma arising in association with hyperparathyroidism.<\/jats:p>","DOI":"10.1359\/jbmr.2003.18.1.163","type":"journal-article","created":{"date-parts":[[2006,4,26]],"date-time":"2006-04-26T21:31:36Z","timestamp":1146087096000},"page":"163-166","source":"Crossref","is-referenced-by-count":31,"title":["Osteosarcoma of Bone in a Patient With Primary Hyperparathyroidism: A Case Report"],"prefix":"10.1093","volume":"18","author":[{"given":"M","family":"Betancourt","sequence":"first","affiliation":[{"name":"Department of Medicine Endocrinology, Baylor College of Medicine, Houston, Texas, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"KL","family":"Wirfel","sequence":"additional","affiliation":[{"name":"Department of Endocrine Neoplasia and Hormonal Disorders, The University of Texas and M.D. Anderson Cancer Center, Houston, Texas, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"AK","family":"Raymond","sequence":"additional","affiliation":[{"name":"Department of Pathology, The University of Texas and M.D. Anderson Cancer Center, Houston, Texas, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"AW","family":"Yasko","sequence":"additional","affiliation":[{"name":"Section of Orthopedic Oncology, Department of Surgical Oncology, The University of Texas and M.D. Anderson Cancer Center, Houston, Texas, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Lee","sequence":"additional","affiliation":[{"name":"Section of Orthopedic Oncology, Department of Surgical Oncology, The University of Texas and M.D. Anderson Cancer Center, Houston, Texas, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Vassilopoulou-Sellin","sequence":"additional","affiliation":[{"name":"Department of Endocrine Neoplasia and Hormonal Disorders, The University of Texas and M.D. Anderson Cancer Center, Houston, Texas, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2009,12,2]]},"reference":[{"key":"2024013019163709300_bib1","first-page":"397","volume-title":"Primer on Metabolic Bone Diseases and Disorders of Mineral Metabolism","author":"Whyte","year":"1999","edition":"4th ed."},{"key":"2024013019163709300_bib2","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1023\/A:1026508829397","article-title":"Clinical spectrum of primary hyperparathyroidism","volume":"1","author":"Bilezekian","year":"2000","journal-title":"Rev Endocrinol Metab Dis"},{"key":"2024013019163709300_bib3","doi-asserted-by":"crossref","first-page":"1434","DOI":"10.1056\/NEJM200105103441904","article-title":"Effect of parathyroid hormone (1\u201334) on fractures and bone mineral density in postmenopausal women with osteoporosis","volume":"344","author":"Neer","year":"2001","journal-title":"N Engl J Med"},{"key":"2024013019163709300_bib4","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1016\/S0140-6736(97)02342-8","article-title":"Randomized, controlled study of effect of parathyroid hormone on vertebral-bone mass and fracture incidence among postmenopausal women on estrogen with osteoporosis","volume":"350","author":"Lindsay","year":"1997","journal-title":"Lancet"},{"key":"2024013019163709300_bib5","first-page":"2129","article-title":"Enhancement of bone mass in osteoporotic women with parathyroid hormone followed by alendronate","volume":"85","author":"Rittmaster","year":"2000","journal-title":"JCEM"},{"key":"2024013019163709300_bib6","author":"Department of Health and Human Services","year":"2002"},{"key":"2024013019163709300_bib7","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/S1043-2760(01)00489-1","article-title":"Osteosarcoma risk in rats using PTH 1\u201334","volume":"12","author":"Barbehen","year":"2001","journal-title":"Lett Trends Endocrinol Metab"},{"key":"2024013019163709300_bib8","first-page":"391","article-title":"Hyperparathyroidism with multiple malignant tumors of bone with giant cells","volume":"137","author":"Wiig","year":"1971","journal-title":"Acta Chir Scand"},{"key":"2024013019163709300_bib9","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1007\/s002560050202","article-title":"Hyperparathyroidism associated with sarcoma of bone","volume":"26","author":"Smith","year":"1997","journal-title":"Skeletal Radiol"}],"container-title":["Journal of Bone and Mineral Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1359%2Fjbmr.2003.18.1.163","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/academic.oup.com\/jbmr\/article-pdf\/18\/1\/163\/56471093\/5650180122.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jbmr\/article-pdf\/18\/1\/163\/56471093\/5650180122.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,13]],"date-time":"2024-03-13T15:05:44Z","timestamp":1710342344000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jbmr\/article\/18\/1\/163-166\/7592500"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,1,1]]},"references-count":9,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2009,12,2]]},"published-print":{"date-parts":[[2003,1,1]]}},"URL":"https:\/\/doi.org\/10.1359\/jbmr.2003.18.1.163","relation":{},"ISSN":["0884-0431","1523-4681"],"issn-type":[{"value":"0884-0431","type":"print"},{"value":"1523-4681","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2003,1,1]]},"published":{"date-parts":[[2003,1,1]]}}}