{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T04:46:45Z","timestamp":1790830005586,"version":"4.1.0"},"reference-count":62,"publisher":"Optica Publishing Group","issue":"14","license":[{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/doi.org\/10.1364\/OA_License_v2#VOR"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/opg.optica.org\/policies\/opg-tdm-policy.json"}],"content-domain":{"domain":["opg.optica.org"],"crossmark-restriction":false},"short-container-title":["Appl. Opt."],"published-print":{"date-parts":[[2024,5,10]]},"abstract":"<jats:p>The preservation method to store bone tissue for posterior analysis is a widespread practice. However, the method\u2019s potential influence on the material\u2019s mechanical properties is often overlooked during single-point experimentation. Saline and formaldehyde solutions are the most common among the employed preservation media. A full field analysis of the mice femoral bone deformation using non-destructive optical techniques is conducted to assess the influence of the storage media on the viscoelastic properties of the tissue. Three different groups are subjected to a standard three-point bending test. The first group is the control, with fresh post-mortem samples. The second and third groups used saline and formaldehyde solutions, respectively. During the mechanical test, the bone\u2019s surface and internal deformation are monitored simultaneously using digital holographic interferometry and Fourier-domain optical coherence tomography. A mechanical comparison among the three groups is presented. The results show that after 48\u00a0h of immersion in saline solution, the mice bones keep their viscoelastic behavior similar to fresh bones. Meanwhile, 48\u00a0h in formaldehyde modifies the response and affects the marrow structure. The high sensitivity of the optical phase also makes it possible to observe changes in the anisotropy of the samples. As a comparison, Raman spectroscopy analyzes the three bone groups to prove that the preservation media does not affect a single-point inspection.<\/jats:p>","DOI":"10.1364\/ao.512047","type":"journal-article","created":{"date-parts":[[2024,4,15]],"date-time":"2024-04-15T11:00:05Z","timestamp":1713178805000},"page":"3745","update-policy":"https:\/\/doi.org\/10.1364\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Impact of the preservation media on ex vivo bone samples for full field mechanical testing"],"prefix":"10.1364","volume":"63","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2390-0103","authenticated-orcid":true,"given":"Brenda M.","family":"Guzman V.","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00q8h8k29","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3091-137X","authenticated-orcid":true,"given":"Manuel H.","family":"De La Torre I.","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00q8h8k29","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudio","family":"Frausto-Reyes","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00q8h8k29","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"285","published-online":{"date-parts":[[2024,5,1]]},"reference":[{"key":"ao-63-14-3745-R1","doi-asserted-by":"publisher","first-page":"4420","DOI":"10.1364\/AO.58.004420","volume":"58","author":"Vishnoi","year":"2019","journal-title":"Appl. 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