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Opt."],"published-print":{"date-parts":[[2025,3,10]]},"abstract":"<jats:p>In this paper, a hydrogel fiber optic sensing probe with a fluorescence indicator doped\n\t\t\t\t\tin the core is proposed for dissolved oxygen detection in blood. The\n\t\t\t\t\thydrogel fiber was made by photocrosslinking with a core-cladding\n\t\t\t\t\tstructure made from PEGDA precursor solutions with different\n\t\t\t\t\tconcentrations. By changing the concentration of the fluorescent\n\t\t\t\t\tindicator doped in the core of the hydrogel optical fiber and changing\n\t\t\t\t\tthe length of the fiber and the thickness of the cladding, the sensing\n\t\t\t\t\tperformance of the fiber for dissolved oxygen was optimized, and it\n\t\t\t\t\twas found that the effect of photobleaching could be reduced\n\t\t\t\t\tappropriately by lowering the excitation power. The resolution is\n\t\t\t\t\t0.008\u00a0ml\/dl, with a linearity of 0.99, and the range is\n\t\t\t\t\t0\u20132.015\u00a0ml\/dl, which makes it suitable for the measurement of\n\t\t\t\t\tthe partial pressure of blood oxygen in human beings. The system also\n\t\t\t\t\tshows good stability and repeatability. Due to the flexibility and\n\t\t\t\t\tbiocompatibility properties, the hydrogel optical fiber dissolved\n\t\t\t\t\toxygen sensing probe has promising application in the biomedical\n\t\t\t\t\tfield.<\/jats:p>","DOI":"10.1364\/ao.543857","type":"journal-article","created":{"date-parts":[[2025,2,5]],"date-time":"2025-02-05T10:00:35Z","timestamp":1738749635000},"page":"1892","update-policy":"https:\/\/doi.org\/10.1364\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Dissolved oxygen sensing characteristics in blood by hydrogel optical fiber"],"prefix":"10.1364","volume":"64","author":[{"given":"Jianglin","family":"Fan","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/02w4tny03","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenglan","family":"Bian","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/02w4tny03","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fenghong","family":"Chu","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/02w4tny03","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wu","family":"Zhu","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/02w4tny03","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bin","family":"Zhou","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/02w4tny03","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"285","published-online":{"date-parts":[[2025,2,27]]},"reference":[{"key":"ao-64-8-1892-R1","first-page":"156","volume":"31","author":"Shengxiang","year":"2011","journal-title":"Chin. 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