{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T12:31:25Z","timestamp":1787315485023,"version":"build-2736575974"},"reference-count":50,"publisher":"Optica Publishing Group","issue":"10","license":[{"start":{"date-parts":[[2020,9,16]],"date-time":"2020-09-16T00:00:00Z","timestamp":1600214400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/doi.org\/10.1364\/OA_License_v1#VOR-OA"},{"start":{"date-parts":[[2020,9,16]],"date-time":"2020-09-16T00:00:00Z","timestamp":1600214400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/opg.optica.org\/policies\/opg-tdm-policy.json"}],"funder":[{"DOI":"10.13039\/100010663","name":"H2020 European Research Council","doi-asserted-by":"publisher","award":["H2020-MSCA COFUND-2015 FP-713694, MULTIPLY (AdC)"],"award-info":[{"award-number":["H2020-MSCA COFUND-2015 FP-713694, MULTIPLY (AdC)"]}],"id":[{"id":"10.13039\/100010663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003329","name":"Ministerio de Econom\u00eda y Competitividad","doi-asserted-by":"publisher","award":["FIS2017- 84753-R"],"award-info":[{"award-number":["FIS2017- 84753-R"]}],"id":[{"id":"10.13039\/501100003329","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010661","name":"Horizon 2020 Framework Programme","doi-asserted-by":"publisher","award":["IMCUSTOMEYE Ref. 779960 (H2020-ICT- 2017-1)"],"award-info":[{"award-number":["IMCUSTOMEYE Ref. 779960 (H2020-ICT- 2017-1)"]}],"id":[{"id":"10.13039\/100010661","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000781","name":"European Research Council","doi-asserted-by":"publisher","award":["ERC-2011-AdG-294099"],"award-info":[{"award-number":["ERC-2011-AdG-294099"]}],"id":[{"id":"10.13039\/501100000781","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01EY021834"],"award-info":[{"award-number":["R01EY021834"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["opg.optica.org"],"crossmark-restriction":false},"short-container-title":["Biomed. Opt. Express"],"published-print":{"date-parts":[[2020,10,1]]},"abstract":"<jats:p>\n                    The crystalline lens is an important optical element in the eye, responsible for focusing, and which experiences significant changes throughout life. The shape of the lens is usually studied only in the optical area (central 4 to 6\u2009mm). However, for a great number of applications, a description of the full shape of the crystalline lens is required. We propose a new method for the representation of the full shape of the crystalline lens, constructed from 3-dimensional optical coherence tomography images of 133 isolated crystalline lenses (0-71 y\/o), which we have called\n                    <jats:italic>eigenlenses<\/jats:italic>\n                    . The method is shown to be compact and accurate to describe not only the full shape of the crystalline lens, but also the optical zone in comparison with other methods. We also demonstrate its application to the extrapolation of the full shape of the crystalline lens from\n                    <jats:italic>in-vivo<\/jats:italic>\n                    optical images of the anterior segment of the eye, where only the central part of the lens visible through the pupil is available, and in the generation (synthesis) of realistic full lenses of a given age. The method has critical applications, among others, in improving and evaluating myopia and presbyopia treatments.\n                  <\/jats:p>","DOI":"10.1364\/boe.397695","type":"journal-article","created":{"date-parts":[[2020,7,24]],"date-time":"2020-07-24T11:30:36Z","timestamp":1595590236000},"page":"5633","update-policy":"https:\/\/doi.org\/10.1364\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Eigenlenses: a new model for full crystalline lens shape representation and its applications"],"prefix":"10.1364","volume":"11","author":[{"given":"Eduardo","family":"Martinez-Enriquez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2873-3412","authenticated-orcid":true,"given":"Alberto","family":"de Castro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susana","family":"Marcos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"285","published-online":{"date-parts":[[2020,9,16]]},"reference":[{"key":"boe-11-10-5633-R1","author":"Atchison","year":"2000"},{"key":"boe-11-10-5633-R2","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1111\/j.1475-1313.1997.tb00518.x","volume":"17","author":"Garner","year":"1997","journal-title":"Ophthalmic Physiol. 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