{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T15:10:46Z","timestamp":1777475446237,"version":"3.51.4"},"reference-count":59,"publisher":"Optica Publishing Group","issue":"3","license":[{"start":{"date-parts":[[2021,2,3]],"date-time":"2021-02-03T00:00:00Z","timestamp":1612310400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/doi.org\/10.1364\/OA_License_v1#VOR-OA"},{"start":{"date-parts":[[2021,2,3]],"date-time":"2021-02-03T00:00:00Z","timestamp":1612310400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/opg.optica.org\/policies\/opg-tdm-policy.json"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01 DK092255"],"award-info":[{"award-number":["R01 DK092255"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007751","name":"Akademia G\u00f3rniczo-Hutnicza im. 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In this study, we report a new technique called two-dimensional (2D) dynamic vibration OCE (DV-OCE) to evaluate 2D wave velocities without tedious focusing alignment procedures and is a non-contact method with respect to the samples. The three-dimensional (3D) Fourier transform was utilized to transfer the traveling waves (<jats:italic toggle=\"yes\">x, y, t<\/jats:italic>) into 3D <jats:italic toggle=\"yes\">k<\/jats:italic>-space (<jats:italic toggle=\"yes\">k<jats:sub>x<\/jats:sub>, k<jats:sub>y<\/jats:sub>, f<\/jats:italic>). A spatial 2D wavenumber filter and multi-angle directional filter were employed to decompose the waves with omni-directional components into four individual traveling directions. The 2D local wave velocity algorithm was used to calculate a 2D wave velocity map. Six materials, two homogeneous phantoms with 10\u2005mm thickness, two homogeneous phantoms with 2\u2005mm thickness, one heterogeneous phantom with 2\u2005mm diameter inclusion and an <jats:italic toggle=\"yes\">ex vivo<\/jats:italic> porcine kidney, were examined in this study. In addition, the ARF-OCE was used to evaluate wave velocities for comparison. Numerical simulations were performed to validate the proposed 2D dynamic vibration OCE technique. We demonstrate that the experimental results were in a good agreement with the results from ARF-OCE (transient OCE) and numerical simulations. Our proposed 2D dynamic vibration OCE could potentially pave the way for mechanical evaluation in tissue engineering and for laboratory translation with easy-to-setup and contactless advantages.<\/jats:p>","DOI":"10.1364\/boe.416661","type":"journal-article","created":{"date-parts":[[2021,1,26]],"date-time":"2021-01-26T07:30:05Z","timestamp":1611646205000},"page":"1217","update-policy":"https:\/\/doi.org\/10.1364\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Two-dimensional (2D) dynamic vibration optical coherence elastography (DV-OCE) for evaluating mechanical properties: a potential application in tissue engineering"],"prefix":"10.1364","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5410-8821","authenticated-orcid":true,"given":"Hsiao-Chuan","family":"Liu","sequence":"first","affiliation":[{"name":"Mayo Clinic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6086-3420","authenticated-orcid":true,"given":"Piotr","family":"Kijanka","sequence":"additional","affiliation":[{"name":"AGH University of Science and Technology"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1360-4287","authenticated-orcid":true,"given":"Matthew W.","family":"Urban","sequence":"additional","affiliation":[{"name":"Mayo Clinic"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"285","published-online":{"date-parts":[[2021,2,3]]},"reference":[{"key":"boe-12-3-1217-R1","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1038\/s41578-019-0169-1","volume":"5","author":"Guimaraes","year":"2020","journal-title":"Nat. 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