{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,4]],"date-time":"2026-03-04T04:20:54Z","timestamp":1772598054046,"version":"3.50.1"},"reference-count":41,"publisher":"Optica Publishing Group","issue":"7","license":[{"start":{"date-parts":[[2021,6,23]],"date-time":"2021-06-23T00:00:00Z","timestamp":1624406400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/doi.org\/10.1364\/OA_License_v1#VOR-OA"},{"start":{"date-parts":[[2021,6,23]],"date-time":"2021-06-23T00:00:00Z","timestamp":1624406400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/opg.optica.org\/policies\/opg-tdm-policy.json"}],"funder":[{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["APP1180854"],"award-info":[{"award-number":["APP1180854"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["2019H1D3A2A02101784"],"award-info":[{"award-number":["2019H1D3A2A02101784"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001801","name":"University of Western Australia","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001801","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["opg.optica.org"],"crossmark-restriction":false},"short-container-title":["Biomed. Opt. Express"],"published-print":{"date-parts":[[2021,7,1]]},"abstract":"<jats:p>A new method based on polarization-sensitive optical coherence tomography (PS-OCT) is introduced to determine the polarization properties of human retinal vessel walls, <jats:italic>in vivo<\/jats:italic>. Measurements were obtained near the optic nerve head of three healthy human subjects. The double pass phase retardation per unit depth (DPPR\/UD), which is proportional to the birefringence, is higher in artery walls, presumably because of the presence of muscle tissue. Measurements in surrounding retinal nerve fiber layer tissue yielded lower DPPR\/UD values, suggesting that the retinal vessel wall tissue near the optic nerve is not covered by retinal nerve fiber layer tissue (0.43\u00b0\/\u00b5m vs. 0.77\u00b0\/\u00b5m, respectively). Measurements were obtained from multiple artery-vein pairs, to quantify the different polarization properties. Measurements were taken along a section of the vessel wall, with changes in DPPR\/UD up to 15%, while the vessel wall thickness remained relatively constant. A stationary scan pattern was applied to determine the influence of involuntary eye motion on the measurement, which was significant. Measurements were also analyzed by two examiners, with high inter-observer agreement. The measurement repeatability was determined with measurements that were acquired during multiple visits. An improvement in accuracy can be achieved with an ultra-broad-bandwidth PS-OCT system since it will provide more data points in-depth, which reduces the influence of discretization and helps to facilitate better fitting of the birefringence data.<\/jats:p>","DOI":"10.1364\/boe.426079","type":"journal-article","created":{"date-parts":[[2021,5,27]],"date-time":"2021-05-27T21:30:27Z","timestamp":1622151027000},"page":"4340","update-policy":"https:\/\/doi.org\/10.1364\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Polarization properties of retinal blood vessel walls measured with polarization sensitive optical coherence tomography"],"prefix":"10.1364","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7874-2766","authenticated-orcid":true,"given":"Hadi","family":"Afsharan","sequence":"first","affiliation":[{"name":"The University of Western Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3940-0397","authenticated-orcid":true,"given":"Michael J.","family":"Hackmann","sequence":"additional","affiliation":[{"name":"The University of Western Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiang","family":"Wang","sequence":"additional","affiliation":[{"name":"The University of Western Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Farzaneh","family":"Navaeipour","sequence":"additional","affiliation":[{"name":"Queen\u2019s University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephy Vijaya Kumar","family":"Jayasree","sequence":"additional","affiliation":[{"name":"The University of Western Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9574-156X","authenticated-orcid":true,"given":"Robert J.","family":"Zawadzki","sequence":"additional","affiliation":[{"name":"University of California Davis"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dilusha","family":"Silva","sequence":"additional","affiliation":[{"name":"The University of Western Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chulmin","family":"Joo","sequence":"additional","affiliation":[{"name":"Yonsei University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7164-8053","authenticated-orcid":true,"given":"Barry","family":"Cense","sequence":"additional","affiliation":[{"name":"The University of Western Australia"},{"name":"Yonsei University"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"285","published-online":{"date-parts":[[2021,6,23]]},"reference":[{"key":"boe-12-7-4340-R1","doi-asserted-by":"publisher","first-page":"1646","DOI":"10.1136\/bjo.2005.072546","volume":"89","author":"Grosso","year":"2005","journal-title":"Br. 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