{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T17:50:30Z","timestamp":1740160230848,"version":"3.37.3"},"reference-count":42,"publisher":"Optica Publishing Group","issue":"8","license":[{"start":{"date-parts":[[2021,7,19]],"date-time":"2021-07-19T00:00:00Z","timestamp":1626652800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/doi.org\/10.1364\/OA_License_v1#VOR-OA"},{"start":{"date-parts":[[2021,7,19]],"date-time":"2021-07-19T00:00:00Z","timestamp":1626652800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/opg.optica.org\/policies\/opg-tdm-policy.json"}],"funder":[{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["108-2221-E-006-207-MY3","110-2221-E-A49-102"],"award-info":[{"award-number":["108-2221-E-006-207-MY3","110-2221-E-A49-102"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["opg.optica.org"],"crossmark-restriction":false},"short-container-title":["Biomed. Opt. Express"],"published-print":{"date-parts":[[2021,8,1]]},"abstract":"<jats:p>In addition to supplying oxygen molecule O<jats:sub>2<\/jats:sub> for metabolic functions during the adaptation to exercise, blood also plays a critical role in heat dissipation for core temperature stabilization. This study investigates the status of hemodynamic oxygenation in the forearm\u2019s skin tissue of three participants during a complete ergometer exercise from the resting to exercising, and to recovering conditions using a three-wavelength frequency-domain diffuse reflectance spectroscopy (FD DRS) alongside the monitoring of heartbeat rate and skin temperature. The FD DRS system was synchronized with radiofrequency (RF)-modulated input photon sources and the respective output to extract time-course absorption and scattering coefficients of the skin tissue, which, through the fitting of lambert\u2019s law of absorbance, can be used to determine the concentration of oxygenated\/deoxygenated hemoglobin molecules, and consequentially, the oxygen saturation of skin tissue and total hemoglobin (THb) concentration. Expressly, a sudden jump in heartbeat rate at the beginning of the exercise, a temporal lag of the rising edge of skin temperature behind that of the THb concentration in the procession of step-wise incremental working intensity, and the uprising of THb in the exhaustion zone in responses to the physiological adaptation to exercise were identified. Finally, conclusive remarks were drawn that the FD DRS system is useful in extracting the hemodynamic properties of forearm skin which is often being neglected in previous exercise physiology studies by DRS-related techniques. The detailed variation of hemodynamic and optical scattering parameters of forearm skin elucidated in the studies can be applied for the analysis of athletes\u2019 physiological status, and may be a potential reference for the design of future wearable devices.<\/jats:p>","DOI":"10.1364\/boe.428207","type":"journal-article","created":{"date-parts":[[2021,7,10]],"date-time":"2021-07-10T03:30:05Z","timestamp":1625887805000},"page":"5023","update-policy":"https:\/\/doi.org\/10.1364\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Monitoring adaptation of skin tissue oxygenation during cycling ergometer exercise by frequency-domain diffuse optical spectroscopy"],"prefix":"10.1364","volume":"12","author":[{"given":"Sheng-Hao","family":"Tseng","sequence":"first","affiliation":[{"name":"National Cheng Kung University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bo-Jian","family":"Liang","sequence":"additional","affiliation":[{"name":"National Cheng Kung University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wen","family":"Wang","sequence":"additional","affiliation":[{"name":"National Cheng Kung University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bo-Xiang","family":"Tsai","sequence":"additional","affiliation":[{"name":"National Yang Ming Chiao Tung University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Po-Sheng","family":"Hu","sequence":"additional","affiliation":[{"name":"National Yang Ming Chiao Tung University"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"285","published-online":{"date-parts":[[2021,7,19]]},"reference":[{"key":"boe-12-8-5023-R1","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1016\/j.transci.2004.06.001","volume":"31","author":"Scheufler","year":"2004","journal-title":"Transfus Apher. 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