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Opt. Express"],"published-print":{"date-parts":[[2022,6,1]]},"abstract":"<jats:p>Otitis media (OM) is an extremely common disease that affects children\n\t\t\t\t\tworldwide. Optical coherence tomography (OCT) has emerged as a\n\t\t\t\t\tnoninvasive diagnostic tool for OM, which can detect the presence and\n\t\t\t\t\tquantify the properties of middle ear fluid and biofilms. Here, the\n\t\t\t\t\tuse of OCT data from the chinchilla, the gold-standard OM model for\n\t\t\t\t\tthe human disease, is used to supplement a human image database to\n\t\t\t\t\tproduce diagnostically relevant conclusions in a machine learning\n\t\t\t\t\tmodel. Statistical analysis shows the datatypes are compatible, with a\n\t\t\t\t\tblended-species model reaching \u223c95% accuracy and F1 score, maintaining\n\t\t\t\t\tperformance while additional human data is collected.<\/jats:p>","DOI":"10.1364\/boe.453536","type":"journal-article","created":{"date-parts":[[2022,5,17]],"date-time":"2022-05-17T15:01:49Z","timestamp":1652799709000},"page":"3601","update-policy":"https:\/\/doi.org\/10.1364\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Automated classification of otitis media with OCT: augmenting pediatric image datasets with gold-standard animal model data"],"prefix":"10.1364","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3669-8514","authenticated-orcid":true,"given":"Guillermo L.","family":"Monroy","sequence":"first","affiliation":[{"name":"Beckman Institute for Advanced Science and Technology"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jungeun","family":"Won","sequence":"additional","affiliation":[{"name":"Beckman Institute for Advanced Science and Technology"},{"name":"University of Illinois at Urbana-Champaign"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jindou","family":"Shi","sequence":"additional","affiliation":[{"name":"Beckman Institute for Advanced Science and Technology"},{"name":"University of Illinois at Urbana-Champaign"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Malcolm C.","family":"Hill","sequence":"additional","affiliation":[{"name":"Carle Foundation Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryan G.","family":"Porter","sequence":"additional","affiliation":[{"name":"Carle Foundation Hospital"},{"name":"University of Illinois at Urbana-Champaign"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael A.","family":"Novak","sequence":"additional","affiliation":[{"name":"Carle Foundation Hospital"},{"name":"University of Illinois at Urbana-Champaign"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenzhou","family":"Hong","sequence":"additional","affiliation":[{"name":"Medical College of Wisconsin"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pawjai","family":"Khampang","sequence":"additional","affiliation":[{"name":"Medical College of Wisconsin"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph E.","family":"Kerschner","sequence":"additional","affiliation":[{"name":"Medical College of Wisconsin"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9946-2659","authenticated-orcid":true,"given":"Darold R.","family":"Spillman","sequence":"additional","affiliation":[{"name":"Beckman Institute for Advanced Science and Technology"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9386-5630","authenticated-orcid":true,"given":"Stephen A.","family":"Boppart","sequence":"additional","affiliation":[{"name":"Beckman Institute for Advanced Science and Technology"},{"name":"University of Illinois at Urbana-Champaign"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"285","published-online":{"date-parts":[[2022,5,26]]},"reference":[{"key":"boe-13-6-3601-R1","first-page":"435","volume":"88","author":"Harmes","year":"2013","journal-title":"Am Fam Physician"},{"key":"boe-13-6-3601-R2","doi-asserted-by":"publisher","first-page":"e964","DOI":"10.1542\/peds.2012-3488","volume":"131","author":"Lieberthal","year":"2013","journal-title":"Pediatrics"},{"key":"boe-13-6-3601-R3","doi-asserted-by":"publisher","first-page":"202","DOI":"10.1001\/jama.296.2.202","volume":"296","author":"Hall-Stoodley","year":"2006","journal-title":"JAMA"},{"key":"boe-13-6-3601-R4","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1177\/0194599818766320","volume":"159","author":"Monroy","year":"2018","journal-title":"Otolaryngol.--Head Neck Surg."},{"key":"boe-13-6-3601-R5","doi-asserted-by":"publisher","first-page":"e00010","DOI":"10.1128\/CMR.00010-18","volume":"32","author":"van den Broek","year":"2019","journal-title":"Clin. 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